Appropriateness of indirect markers of muscle damage following lower limbs eccentric-biased exercises: A systematic review with meta-analysis.


Journal

PloS one
ISSN: 1932-6203
Titre abrégé: PLoS One
Pays: United States
ID NLM: 101285081

Informations de publication

Date de publication:
2022
Historique:
received: 16 03 2022
accepted: 25 06 2022
entrez: 14 7 2022
pubmed: 15 7 2022
medline: 19 7 2022
Statut: epublish

Résumé

The aim of this review was to (1) characterize the time-course of markers of exercise-induced muscle damage (EIMD) based on the level of maximal voluntary contraction torque loss at 24-48h post-exercise (MVCloss24-48h), (2) identify factors (e.g., exercise and population characteristics) affecting the level of MVCloss24-48h, and (3) evaluate the appropriateness of EIMD markers as indicators of MVCloss24-48h. Magnitude of change of each EIMD markers was normalized using the standardized mean differences method to compare the results from different studies. Time-course of EIMD markers were characterized according to three levels of MVCloss24-48h based on a clustering analysis of the 141 studies included. Association between MVCloss24-48h levels and participant´s characteristics or exercise type/modalities were assessed. Meta-regressions were performed to investigate the associations between MVCloss24-48h and EIMD markers changes at <6h, 24h, 48h, 72h and >96h after exercise. Time-course of EIMD markers recovery differs between levels of MVCloss24-48h. Training status and exercise type/modality were associated with MVCloss24-48h level (p<0.05). MVCloss24-48h was correlated to changes in myoglobin concentration (<6h), jump height (24h) and range of motion (48h) (p<0.001). As the exercise could differently affect markers as function of the EIMD severity (i.e., MVCloss24-48h levels), different markers should be used as function of the timing of measurement. Mb concentration should be used during the first hours after the exercise (<6h), whereas jump height (24h) and range of motion (48h) could be used as surrogate for maximal voluntary contraction later. Moreover, training status and exercise type/modality could influence the magnitude of MVCloss24-48h.

Identifiants

pubmed: 35834532
doi: 10.1371/journal.pone.0271233
pii: PONE-D-22-07742
pmc: PMC9282447
doi:

Substances chimiques

Biomarkers 0

Types de publication

Journal Article Meta-Analysis Systematic Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

e0271233

Déclaration de conflit d'intérêts

The authors have declared that no competing interests exist.

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Auteurs

Emeric Chalchat (E)

Institut de Recherche Biomédicale des Armées, Unité de Physiologie des Exercices et Activités en Conditions Extrêmes, Département Environnements Opérationnels, Bretigny-Sur-Orge, France.
Université Clermont Auvergne, AME2P, Clermont-Ferrand, France.

Anne-Fleur Gaston (AF)

Laboratoire Interdisciplinaire Performance Santé Environnement de Montagne, Université de Perpignan, Perpignan, France.

Keyne Charlot (K)

Institut de Recherche Biomédicale des Armées, Unité de Physiologie des Exercices et Activités en Conditions Extrêmes, Département Environnements Opérationnels, Bretigny-Sur-Orge, France.
LBEPS, Univ Evry, IRBA, Université Paris Saclay, Evry, France.

Luis Peñailillo (L)

Exercise and Rehabilitation Sciences Laboratory, School of Physical Therapy, Faculty of Rehabilitation Sciences, Universidad Andres Bello, Santiago, Chile.

Omar Valdés (O)

Exercise Science Laboratory, School of Kinesiology, Faculty of Medicine, Universidad Finis Terrae, Santiago, Chile.

Pierre-Emmanuel Tardo-Dino (PE)

Institut de Recherche Biomédicale des Armées, Unité de Physiologie des Exercices et Activités en Conditions Extrêmes, Département Environnements Opérationnels, Bretigny-Sur-Orge, France.
LBEPS, Univ Evry, IRBA, Université Paris Saclay, Evry, France.

Kazunori Nosaka (K)

Centre for Exercise and Sports Science Research, School of Medical and Health Sciences, Edith Cowan University, Joondalup, WA, Australia.

Vincent Martin (V)

Université Clermont Auvergne, AME2P, Clermont-Ferrand, France.
Institut Universitaire de France (IUF), Paris, France.

Sebastian Garcia-Vicencio (S)

Institut de Recherche Biomédicale des Armées, Unité de Physiologie des Exercices et Activités en Conditions Extrêmes, Département Environnements Opérationnels, Bretigny-Sur-Orge, France.
LBEPS, Univ Evry, IRBA, Université Paris Saclay, Evry, France.

Julien Siracusa (J)

Institut de Recherche Biomédicale des Armées, Unité de Physiologie des Exercices et Activités en Conditions Extrêmes, Département Environnements Opérationnels, Bretigny-Sur-Orge, France.
LBEPS, Univ Evry, IRBA, Université Paris Saclay, Evry, France.

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