Benchmarking of minimally invasive distal pancreatectomy with splenectomy: European multicentre study.


Journal

The British journal of surgery
ISSN: 1365-2168
Titre abrégé: Br J Surg
Pays: England
ID NLM: 0372553

Informations de publication

Date de publication:
14 10 2022
Historique:
received: 23 02 2022
revised: 14 04 2022
accepted: 17 05 2022
pubmed: 15 7 2022
medline: 19 10 2022
entrez: 14 7 2022
Statut: ppublish

Résumé

Benchmarking is the process to used assess the best achievable results and compare outcomes with that standard. This study aimed to assess best achievable outcomes in minimally invasive distal pancreatectomy with splenectomy (MIDPS). This retrospective study included consecutive patients undergoing MIDPS for any indication, between 2003 and 2019, in 31 European centres. Benchmarks of the main clinical outcomes were calculated according to the Achievable Benchmark of Care (ABC™) method. After identifying independent risk factors for severe morbidity and conversion, risk-adjusted ABCs were calculated for each subgroup of patients at risk. A total of 1595 patients were included. The ABC was 2.5 per cent for conversion and 8.4 per cent for severe morbidity. ABC values were 160 min for duration of operation time, 8.3 per cent for POPF, 1.8 per cent for reoperation, and 0 per cent for mortality. Multivariable analysis showed that conversion was associated with male sex (OR 1.48), BMI exceeding 30 kg/m2 (OR 2.42), multivisceral resection (OR 3.04), and laparoscopy (OR 2.24). Increased risk of severe morbidity was associated with ASA fitness grade above II (OR 1.60), multivisceral resection (OR 1.88), and robotic approach (OR 1.87). The benchmark values obtained using the ABC method represent optimal outcomes from best achievable care, including low complication rates and zero mortality. These benchmarks should be used to set standards to improve patient outcomes.

Sections du résumé

BACKGROUND
Benchmarking is the process to used assess the best achievable results and compare outcomes with that standard. This study aimed to assess best achievable outcomes in minimally invasive distal pancreatectomy with splenectomy (MIDPS).
METHODS
This retrospective study included consecutive patients undergoing MIDPS for any indication, between 2003 and 2019, in 31 European centres. Benchmarks of the main clinical outcomes were calculated according to the Achievable Benchmark of Care (ABC™) method. After identifying independent risk factors for severe morbidity and conversion, risk-adjusted ABCs were calculated for each subgroup of patients at risk.
RESULTS
A total of 1595 patients were included. The ABC was 2.5 per cent for conversion and 8.4 per cent for severe morbidity. ABC values were 160 min for duration of operation time, 8.3 per cent for POPF, 1.8 per cent for reoperation, and 0 per cent for mortality. Multivariable analysis showed that conversion was associated with male sex (OR 1.48), BMI exceeding 30 kg/m2 (OR 2.42), multivisceral resection (OR 3.04), and laparoscopy (OR 2.24). Increased risk of severe morbidity was associated with ASA fitness grade above II (OR 1.60), multivisceral resection (OR 1.88), and robotic approach (OR 1.87).
CONCLUSION
The benchmark values obtained using the ABC method represent optimal outcomes from best achievable care, including low complication rates and zero mortality. These benchmarks should be used to set standards to improve patient outcomes.

Identifiants

pubmed: 35834788
pii: 6644640
doi: 10.1093/bjs/znac204
doi:

Types de publication

Journal Article Multicenter Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

1124-1130

Informations de copyright

© The Author(s) 2022. Published by Oxford University Press on behalf of BJS Society Ltd. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Auteurs

Alessandro Giani (A)

Division of Minimally Invasive Surgical Oncology, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.
Department of General Surgery, Istituto Ospedaliero Fondazione Poliambulanza, Brescia, Italy.

Tess van Ramshorst (T)

Department of General Surgery, Istituto Ospedaliero Fondazione Poliambulanza, Brescia, Italy.
Department of Surgery, Amsterdam UMC, University of Amsterdam, Cancer Centre Amsterdam, Amsterdam, the Netherlands.

Michele Mazzola (M)

Division of Minimally Invasive Surgical Oncology, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.

Claudio Bassi (C)

Department of Surgery, Pancreas Institute, Verona University Hospital, Verona, Italy.

Alessandro Esposito (A)

Department of Surgery, Pancreas Institute, Verona University Hospital, Verona, Italy.

Matteo de Pastena (M)

Department of Surgery, Pancreas Institute, Verona University Hospital, Verona, Italy.

Bjørn Edwin (B)

Intervention Centre and Department of Hepatopancreatobiliary Surgery, Oslo University Hospital and Institute of Medicine, University of Oslo, OsloNorway.

Mushegh Sahakyan (M)

Intervention Centre and Department of Hepatopancreatobiliary Surgery, Oslo University Hospital and Institute of Medicine, University of Oslo, OsloNorway.

Dyre Kleive (D)

Intervention Centre and Department of Hepatopancreatobiliary Surgery, Oslo University Hospital and Institute of Medicine, University of Oslo, OsloNorway.

Asif Jah (A)

Department of Surgery, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.

Stijn van Laarhoven (S)

Department of Surgery, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.

Ugo Boggi (U)

Department of Surgery, University Hospital of Pisa, Pisa, Italy.

Emanuele Federico Kauffman (EF)

Department of Surgery, University Hospital of Pisa, Pisa, Italy.

Riccardo Casadei (R)

Department of Surgery, Sant'Orsola Malpighi Hospital, Bologna, Italy.

Claudio Ricci (C)

Department of Surgery, Sant'Orsola Malpighi Hospital, Bologna, Italy.

Safi Dokmak (S)

Department of Hepatopancreatobiliary Surgery and Liver Transplantation, Beaujon Hospital, Clichy, France.

Fadhel Samir Ftériche (FS)

Department of Hepatopancreatobiliary Surgery and Liver Transplantation, Beaujon Hospital, Clichy, France.

Steven A White (SA)

Department of Surgery, Freeman Hospital Newcastle upon Tyne, Newcastle upon Tyne, UK.

Sivesh K Kamarajah (SK)

Department of Surgery, Freeman Hospital Newcastle upon Tyne, Newcastle upon Tyne, UK.

Giovanni Butturini (G)

Department of Surgery, Pederzoli Hospital, Peschiera, Italy.

Isabella Frigerio (I)

Department of Surgery, Pederzoli Hospital, Peschiera, Italy.

Alessandro Zerbi (A)

Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Italy.
IRCCS Humanitas Research Hospital, Rozzano, Italy.

Giovanni Capretti (G)

Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Italy.
IRCCS Humanitas Research Hospital, Rozzano, Italy.

Elizabeth Pando (E)

Department of Surgery, Vall d'Hebron University Hospital, Barcelona, Spain.

Robert P Sutcliffe (RP)

Department of Hepatopancreatobiliary Surgery, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.

Ravi Marudanayagam (R)

Department of Hepatopancreatobiliary Surgery, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.

Giuseppe Kito Fusai (GK)

Hepatopancreatobiliary and Liver Transplant Unit, Royal Free London, London, UK.

Jean Michel Fabre (JM)

Department of Surgery, Saint-Éloi Hospital, Montpellier, France.

Bergthor Björnsson (B)

Department of Surgery in Linköping and Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.

Lea Timmermann (L)

Department of Surgery, Charité, Berlin, Germany.

Zahir Soonawalla (Z)

Department of Surgery, Oxford University Hospital, Oxford, UK.

Fernando Burdio (F)

Department of Surgery, University Hospital del Mar, Barcelona, Spain.

Tobias Keck (T)

Department of Surgery, University Medical Centre Schleswig-Holstein, Campus Lübeck, Lübeck, Germany.

Thilo Hackert (T)

Department of Surgery, Heidelberg University Hospital, Heidelberg, Germany.

Bas Groot Koerkamp (B)

Department of Surgery, Erasmus Medical Centre, Rotterdam, theNetherlands.

Mathieu d'Hondt (M)

Department of Digestive and Hepatobiliary/Pancreatic Surgery, Groeninge Hospital, Kortrijk, Belgium.

Andrea Coratti (A)

Division of Oncological and Robotic General Surgery, Careggi University Hospital, Florence, Italy.

Patrick Pessaux (P)

Division of Hepato-Biliary and Pancreatic Surgery, Nouvel Hôpital Civil, University Hospital, Institut Hospitalo-Universitaire de Strasbourg, Strasbourg, France.

Andrea Pietrabissa (A)

Department of Surgery, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.

Bilal Al-Sarireh (B)

Department of Surgery, Morriston Hospital, Swansea, UK.

Marco V Marino (MV)

General and Emergency Surgery Department, Azienda Ospedaliera Ospedali Riuniti Villa Sofia-Cervello, Palermo, Italy.
General Surgery Department, Istituto Villa Salus, Siracusa, Italy.

Quintus Molenaar (Q)

Department of Surgery, UMC Utrecht Cancer Centre, University Medical Centre Utrecht, Utrecht, the Netherlands.

Vincent Yip (V)

Department of Hepatopancreatobiliary Surgery, Royal London Hospital, Barts Health NHS Trust, London, UK.

Marc Besselink (M)

Department of Surgery, Amsterdam UMC, University of Amsterdam, Cancer Centre Amsterdam, Amsterdam, the Netherlands.

Giovanni Ferrari (G)

Division of Minimally Invasive Surgical Oncology, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.

Mohammad Abu Hilal (MA)

Department of General Surgery, Istituto Ospedaliero Fondazione Poliambulanza, Brescia, Italy.

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