T helper profile in pregnant women recovered from COVID-19.
COVID-19
Pregnancy
T helper cells
Journal
Journal of reproductive immunology
ISSN: 1872-7603
Titre abrégé: J Reprod Immunol
Pays: Ireland
ID NLM: 8001906
Informations de publication
Date de publication:
09 2022
09 2022
Historique:
received:
03
03
2022
revised:
04
07
2022
accepted:
05
07
2022
pubmed:
16
7
2022
medline:
20
9
2022
entrez:
15
7
2022
Statut:
ppublish
Résumé
T helper (Th) cell subsets play distinct and important roles during pregnancy. This work was focused on investigating the Th and cytokine profile in pregnant women recovered from COVID-19. To this aim, the frequency of Th1, Th2, Th17 subsets and the level of associated cytokines were analysed in pregnant women recovered from COVID-19 and in matched non-pregnant women. Principal component analysis highlighted a significant impact of pregnancy on Th profile with an increase of ex-Th17 subset and a parallel decrease of Th1 population. These modulations may participate in both preserving the pregnancy and reducing the risk of severe infection.
Identifiants
pubmed: 35839525
pii: S0165-0378(22)00190-5
doi: 10.1016/j.jri.2022.103661
pmc: PMC9258427
pii:
doi:
Substances chimiques
Cytokines
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
103661Informations de copyright
Copyright © 2022 The Authors. Published by Elsevier B.V. All rights reserved.
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