Development of Bovine Gastric Organoids as a Novel
Ostertagia ostertagi
gastrointestinal
host-pathogen interactions
nematodes
three-dimensional (3D) organoids
tissue remodelling
Journal
Frontiers in cellular and infection microbiology
ISSN: 2235-2988
Titre abrégé: Front Cell Infect Microbiol
Pays: Switzerland
ID NLM: 101585359
Informations de publication
Date de publication:
2022
2022
Historique:
received:
25
03
2022
accepted:
24
05
2022
entrez:
18
7
2022
pubmed:
19
7
2022
medline:
20
7
2022
Statut:
epublish
Résumé
Gastro-intestinal nematode (GIN) parasites are a major cause of production losses in grazing cattle, primarily through reduced growth rates in young animals. Control of these parasites relies heavily on anthelmintic drugs; however, with growing reports of resistance to currently available anthelmintics, alternative methods of control are required. A major hurdle in this work has been the lack of physiologically relevant
Identifiants
pubmed: 35846775
doi: 10.3389/fcimb.2022.904606
pmc: PMC9281477
doi:
Substances chimiques
Anthelmintics
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
904606Subventions
Organisme : Biotechnology and Biological Sciences Research Council
ID : BS/E/D/20002173
Pays : United Kingdom
Informations de copyright
Copyright © 2022 Faber, Smith, Price, Steele, Hildersley, Morrison, Mabbott, Nisbet and McNeilly.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. This study received funding from Zoetis. The funder had the following involvement with the study: the decision to submit the manuscript for publication.
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