Neil A Mabbott

Affiliations

Roslin Institute, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, United Kingdom.

Publications (35)

Corrigendum: To the Skin and Beyond: The Immune Response to African Trypanosomes as They Enter and Exit the Vertebrate Host.

Frontiers in immunology

Avec: Omar A Alfituri , Juan F Quintana , Annette MacLeod , Paul Garside , Robert A Benson , James M Brewer , Neil A Mabbott , Liam J Morrison , Paul Capewell

Differential role of M cells in enteroid infection by

Frontiers in cellular and infection microbiology

Avec: Omar A Alfituri , Rosemary Blake , Kirsty Jensen , Neil A Mabbott , Jayne Hope , Joanne M Stevens

Vitamin D

Immunotherapy advances

Avec: Emma S Chambers , Milica Vukmanovic-Stejic , Carolin T Turner , Barbara B Shih , Hugh Trahair , Gabriele Pollara , Evdokia Tsaliki , Malcolm Rustin , Tom C Freeman , Neil A Mabbott , Mahdad Noursadeghi , Adrian R Martineau , Arne N Akbar

The murine meninges acquire lymphoid tissue properties and harbour autoreactive B cells during chronic Trypanosoma brucei infection.

PLoS biology

Avec: Juan F Quintana , Matthew C Sinton , Praveena Chandrasegaran , Lalit Kumar Dubey , John Ogunsola , Moumen Al Samman , Michael Haley , Gail McConnell , Nono-Raymond Kuispond Swar , Dieudonné Mumba Ngoyi , David Bending , Luis de Lecea , Annette MacLeod , Neil A Mabbott

Type I interferon induces CXCL13 to support ectopic germinal center formation.

The Journal of experimental medicine

Avec: Alice E Denton , Silvia Innocentin , Edward J Carr , Barry M Bradford , Fanny Lafouresse , Neil A Mabbott , Urs Mörbe , Burkhard Ludewig , Joanna R Groom , Kim L Good-Jacobson , Michelle A Linterman

Effect of co-infection with a small intestine-restricted helminth pathogen on oral prion disease pathogenesis in mice.

Scientific reports

Avec: Alejandra Sánchez-Quintero , Barry M Bradford , Rick Maizels , David S Donaldson , Neil A Mabbott

Shiga toxin sub-type 2a increases the efficiency of Escherichia coli O157 transmission between animals and restricts epithelial regeneration in bovine enteroids.

PLoS pathogens

Avec: Stephen F Fitzgerald , Amy E Beckett , Javier Palarea-Albaladejo , Sean McAteer , Sharif Shaaban , Jason Morgan , Nur Indah Ahmad , Rachel Young , Neil A Mabbott , Liam Morrison , James L Bono , David L Gally , Tom N McNeilly

Unaltered intravenous prion disease pathogenesis in the temporary absence of marginal zone B cells.

Scientific reports

Avec: Barry M Bradford , Neil A Mabbott

Dendritic cells overcome Cre/Lox induced gene deficiency by siphoning cytosolic material from surrounding cells.

iScience

Avec: Christopher H Herbst , Aurélie Bouteau , Evelin J Menykő , Zhen Qin , Ervin Gyenge , Qingtai Su , Vincent Cooper , Neil A Mabbott , Botond Z Igyártó

Microbial Stimulation Reverses the Age-Related Decline in M Cells in Aged Mice.

iScience

Avec: David S Donaldson , Jolinda Pollock , Prerna Vohra , Mark P Stevens , Neil A Mabbott

Sestrins induce natural killer function in senescent-like CD8

Nature immunology

Avec: Branca I Pereira , Roel P H De Maeyer , Luciana P Covre , Djamel Nehar-Belaid , Alessio Lanna , Sophie Ward , Radu Marches , Emma S Chambers , Daniel C O Gomes , Natalie E Riddell , Mala K Maini , Vitor H Teixeira , Samuel M Janes , Derek W Gilroy , Anis Larbi , Neil A Mabbott , Duygu Ucar , George A Kuchel , Sian M Henson , Jessica Strid , Jun H Lee , Jacques Banchereau , Arne N Akbar

Discrimination of Prion Strain Targeting in the Central Nervous System via Reactive Astrocyte Heterogeneity in CD44 Expression.

Frontiers in cellular neuroscience

Avec: Barry M Bradford , Christianus A W Wijaya , Neil A Mabbott

Antigen Sampling

Frontiers in immunology

Avec: Adam Balic , Cosmin Chintoan-Uta , Prerna Vohra , Kate M Sutton , Robin L Cassady-Cain , Tuan Hu , David S Donaldson , Mark P Stevens , Neil A Mabbott , David A Hume , Helen M Sang , Lonneke Vervelde

Effects of host-derived chemokines on the motility and viability of Trypanosoma brucei.

Parasite immunology

Avec: Omar A Alfituri , Olumide Ajibola , James M Brewer , Paul Garside , Robert A Benson , Tamlyn Peel , Liam J Morrison , Neil A Mabbott

Aging-Related Impairments to M Cells in Peyer's Patches Coincide With Disturbances to Paneth Cells.

Frontiers in immunology

Avec: David S Donaldson , Barbara B Shih , Neil A Mabbott

Accelerated onset of CNS prion disease in mice co-infected with a gastrointestinal helminth pathogen during the preclinical phase.

Scientific reports

Avec: David S Donaldson , Barry M Bradford , Kathryn J Else , Neil A Mabbott

IL-17 signalling is critical for controlling subcutaneous adipose tissue dynamics and parasite burden during chronic murine Trypanosoma brucei infection.

Nature communications

Avec: Matthew C Sinton , Praveena R G Chandrasegaran , Paul Capewell , Anneli Cooper , Alex Girard , John Ogunsola , Georgia Perona-Wright , Dieudonné M Ngoyi , Nono Kuispond , Bruno Bucheton , Mamadou Camara , Shingo Kajimura , Cécile Bénézech , Neil A Mabbott , Annette MacLeod , Juan F Quintana

Development of Bovine Gastric Organoids as a Novel

Frontiers in cellular and infection microbiology

Avec: Marc N Faber , David Smith , Daniel R G Price , Philip Steele , Katie A Hildersley , Liam J Morrison , Neil A Mabbott , Alasdair J Nisbet , Tom N McNeilly

Recruitment of inflammatory monocytes by senescent fibroblasts inhibits antigen-specific tissue immunity during human aging.

Nature aging

Avec: Emma S Chambers , Milica Vukmanovic-Stejic , Barbara B Shih , Hugh Trahair , Priya Subramanian , Oliver P Devine , James Glanville , Derek Gilroy , Malcolm H A Rustin , Tom C Freeman , Neil A Mabbott , Arne N Akbar

To the Skin and Beyond: The Immune Response to African Trypanosomes as They Enter and Exit the Vertebrate Host.

Frontiers in immunology

Avec: Omar A Alfituri , Juan F Quintana , Annette MacLeod , Paul Garside , Robert A Benson , James M Brewer , Neil A Mabbott , Liam J Morrison , Paul Capewell

Influence of the Draining Lymph Nodes and Organized Lymphoid Tissue Microarchitecture on Susceptibility to Intradermal

Frontiers in immunology

Avec: Omar A Alfituri , Barry M Bradford , Edith Paxton , Liam J Morrison , Neil A Mabbott

The clinical correlates of vaccine-induced immune thrombotic thrombocytopenia after immunisation with adenovirus vector-based SARS-CoV-2 vaccines.

Immunotherapy advances

Avec: Eleanor R Gaunt , Neil A Mabbott

Dermal bacterial LPS-stimulation reduces susceptibility to intradermal Trypanosoma brucei infection.

Scientific reports

Avec: Omar A Alfituri , Enock M Mararo , Pieter C Steketee , Liam J Morrison , Neil A Mabbott

The Effects of Immune System Modulation on Prion Disease Susceptibility and Pathogenesis.

International journal of molecular sciences

Avec: Neil A Mabbott , Barry M Bradford , Reiss Pal , Rachel Young , David S Donaldson

Continued Bcl6 Expression Prevents the Transdifferentiation of Established Tfh Cells into Th1 Cells during Acute Viral Infection.

Cell reports

Avec: Dominik Alterauge , Johannes W Bagnoli , Frank Dahlström , Barry M Bradford , Neil A Mabbott , Thorsten Buch , Wolfgang Enard , Dirk Baumjohann

Microglia deficiency accelerates prion disease but does not enhance prion accumulation in the brain.

Glia

Avec: Barry M Bradford , Lynne I McGuire , David A Hume , Clare Pridans , Neil A Mabbott

Innate Immune Tolerance in Microglia Does Not Impact on Central Nervous System Prion Disease.

Frontiers in cellular neuroscience

Avec: Reiss Pal , Barry M Bradford , Neil A Mabbott

Defining the pig microglial transcriptome reveals its core signature, regional heterogeneity, and similarity with human and rodent microglia.

Glia

Avec: Barbara B Shih , Sarah M Brown , Jack Barrington , Lucas Lefevre , Neil A Mabbott , Josef Priller , Gerard Thompson , Alistair B Lawrence , Barry W McColl

Single cell and spatial transcriptomic analyses reveal microglia-plasma cell crosstalk in the brain during Trypanosoma brucei infection.

Nature communications

Avec: Juan F Quintana , Praveena Chandrasegaran , Matthew C Sinton , Emma M Briggs , Thomas D Otto , Rhiannon Heslop , Calum Bentley-Abbot , Colin Loney , Luis de Lecea , Neil A Mabbott , Annette MacLeod

Temporal transcriptome profiling of floating apical out chicken enteroids suggest stability and reproducibility.

Veterinary research

Avec: Tessa J Nash , Katrina M Morris , Neil A Mabbott , Lonneke Vervelde

Dendritic Cells Overcome Cre/Lox Induced Gene Deficiency by Siphoning Material From Neighboring Cells Using Intracellular Monitoring-a Novel Mechanism of Antigen Acquisition.

bioRxiv : the preprint server for biology

Avec: Christopher H Herbst , Aurélie Bouteau , Evelin J Menykő , Zhen Qin , Qingtai Su , Dunia M Buelvas , Ervin Gyenge , Neil A Mabbott , Botond Z Igyártó

Efficacy of smallpox vaccines against Mpox infections in humans.

Immunotherapy advances

Avec: Melissa M Christodoulidou , Neil A Mabbott

Deletion of a Csf1r enhancer selectively impacts CSF1R expression and development of tissue macrophage populations.

Nature communications

Avec: Rocío Rojo , Anna Raper , Derya D Ozdemir , Lucas Lefevre , Kathleen Grabert , Evi Wollscheid-Lengeling , Barry Bradford , Melanie Caruso , Iveta Gazova , Alejandra Sánchez , Zofia M Lisowski , Joana Alves , Irene Molina-Gonzalez , Hayk Davtyan , Rebecca J Lodge , James D Glover , Robert Wallace , David A D Munro , Eyal David , Ido Amit , Véronique E Miron , Josef Priller , Stephen J Jenkins , Giles E Hardingham , Mathew Blurton-Jones , Neil A Mabbott , Kim M Summers , Peter Hohenstein , David A Hume , Clare Pridans

Antigen-presenting ILC3 regulate T cell-dependent IgA responses to colonic mucosal bacteria.

The Journal of experimental medicine

Avec: Felipe Melo-Gonzalez , Hana Kammoun , Elza Evren , Emma E Dutton , Markella Papadopoulou , Barry M Bradford , Ceylan Tanes , Fahmina Fardus-Reid , Jonathan R Swann , Kyle Bittinger , Neil A Mabbott , Bruce A Vallance , Tim Willinger , David R Withers , Matthew R Hepworth

Inside-out chicken enteroids with leukocyte component as a model to study host-pathogen interactions.

Communications biology

Avec: Tessa J Nash , Katrina M Morris , Neil A Mabbott , Lonneke Vervelde

Réseau de co-auteurs

Barry M Bradford 11 collaborations

Omar A Alfituri 6 collaborations

Liam J Morrison 6 collaborations

David S Donaldson 6 collaborations

Juan F Quintana 5 collaborations

Annette MacLeod 5 collaborations

Barbara B Shih 4 collaborations

Paul Garside 3 collaborations

Robert A Benson 3 collaborations

James M Brewer 3 collaborations

Paul Capewell 3 collaborations

Emma S Chambers 3 collaborations

Arne N Akbar 3 collaborations

Matthew C Sinton 3 collaborations

David A Hume 3 collaborations

Lonneke Vervelde 3 collaborations

Milica Vukmanovic-Stejic 2 collaborations

Hugh Trahair 2 collaborations

Tom C Freeman 2 collaborations

Praveena Chandrasegaran 2 collaborations

John Ogunsola 2 collaborations

Luis de Lecea 2 collaborations

Rachel Young 2 collaborations

Tom N McNeilly 2 collaborations

Christopher H Herbst 2 collaborations

Aurélie Bouteau 2 collaborations

Evelin J Menykő 2 collaborations

Zhen Qin 2 collaborations

Ervin Gyenge 2 collaborations

Qingtai Su 2 collaborations

Botond Z Igyártó 2 collaborations

Prerna Vohra 2 collaborations

Mark P Stevens 2 collaborations

Reiss Pal 2 collaborations

Clare Pridans 2 collaborations

Lucas Lefevre 2 collaborations

Josef Priller 2 collaborations

Tessa J Nash 2 collaborations

Katrina M Morris 2 collaborations

Rosemary Blake 1 collaboration

Kirsty Jensen 1 collaboration

Jayne Hope 1 collaboration

Joanne M Stevens 1 collaboration

Carolin T Turner 1 collaboration

Gabriele Pollara 1 collaboration

Evdokia Tsaliki 1 collaboration

Malcolm Rustin 1 collaboration

Mahdad Noursadeghi 1 collaboration

Adrian R Martineau 1 collaboration

Lalit Kumar Dubey 1 collaboration

Moumen Al Samman 1 collaboration

Michael Haley 1 collaboration

Gail McConnell 1 collaboration

Nono-Raymond Kuispond Swar 1 collaboration

Dieudonné Mumba Ngoyi 1 collaboration

David Bending 1 collaboration

Alice E Denton 1 collaboration

Silvia Innocentin 1 collaboration

Edward J Carr 1 collaboration

Fanny Lafouresse 1 collaboration

Urs Mörbe 1 collaboration

Burkhard Ludewig 1 collaboration

Joanna R Groom 1 collaboration

Kim L Good-Jacobson 1 collaboration

Michelle A Linterman 1 collaboration

Alejandra Sánchez-Quintero 1 collaboration

Rick Maizels 1 collaboration

Stephen F Fitzgerald 1 collaboration

Amy E Beckett 1 collaboration

Javier Palarea-Albaladejo 1 collaboration

Sean McAteer 1 collaboration

Sharif Shaaban 1 collaboration

Jason Morgan 1 collaboration

Nur Indah Ahmad 1 collaboration

Liam Morrison 1 collaboration

James L Bono 1 collaboration

David L Gally 1 collaboration

Vincent Cooper 1 collaboration

Jolinda Pollock 1 collaboration

Branca I Pereira 1 collaboration

Roel P H De Maeyer 1 collaboration

Luciana P Covre 1 collaboration

Djamel Nehar-Belaid 1 collaboration

Alessio Lanna 1 collaboration

Sophie Ward 1 collaboration

Radu Marches 1 collaboration

Daniel C O Gomes 1 collaboration

Natalie E Riddell 1 collaboration

Mala K Maini 1 collaboration

Vitor H Teixeira 1 collaboration

Samuel M Janes 1 collaboration

Derek W Gilroy 1 collaboration

Anis Larbi 1 collaboration

Duygu Ucar 1 collaboration

George A Kuchel 1 collaboration

Sian M Henson 1 collaboration

Jessica Strid 1 collaboration

Jun H Lee 1 collaboration

Jacques Banchereau 1 collaboration

Christianus A W Wijaya 1 collaboration

Adam Balic 1 collaboration

Cosmin Chintoan-Uta 1 collaboration

Kate M Sutton 1 collaboration

Robin L Cassady-Cain 1 collaboration

Tuan Hu 1 collaboration

Helen M Sang 1 collaboration

Olumide Ajibola 1 collaboration

Tamlyn Peel 1 collaboration

Kathryn J Else 1 collaboration

Praveena R G Chandrasegaran 1 collaboration

Anneli Cooper 1 collaboration

Alex Girard 1 collaboration

Georgia Perona-Wright 1 collaboration

Dieudonné M Ngoyi 1 collaboration

Nono Kuispond 1 collaboration

Bruno Bucheton 1 collaboration

Mamadou Camara 1 collaboration

Shingo Kajimura 1 collaboration

Cécile Bénézech 1 collaboration

Marc N Faber 1 collaboration

David Smith 1 collaboration

Daniel R G Price 1 collaboration

Philip Steele 1 collaboration

Katie A Hildersley 1 collaboration

Alasdair J Nisbet 1 collaboration

Priya Subramanian 1 collaboration

Oliver P Devine 1 collaboration

James Glanville 1 collaboration

Derek Gilroy 1 collaboration

Malcolm H A Rustin 1 collaboration

Edith Paxton 1 collaboration

Eleanor R Gaunt 1 collaboration

Enock M Mararo 1 collaboration

Pieter C Steketee 1 collaboration

Dominik Alterauge 1 collaboration

Johannes W Bagnoli 1 collaboration

Frank Dahlström 1 collaboration

Thorsten Buch 1 collaboration

Wolfgang Enard 1 collaboration

Dirk Baumjohann 1 collaboration

Lynne I McGuire 1 collaboration

Sarah M Brown 1 collaboration

Jack Barrington 1 collaboration

Gerard Thompson 1 collaboration

Alistair B Lawrence 1 collaboration

Barry W McColl 1 collaboration

Emma M Briggs 1 collaboration

Thomas D Otto 1 collaboration

Rhiannon Heslop 1 collaboration

Calum Bentley-Abbot 1 collaboration

Colin Loney 1 collaboration

Dunia M Buelvas 1 collaboration

Melissa M Christodoulidou 1 collaboration

Rocío Rojo 1 collaboration

Anna Raper 1 collaboration

Derya D Ozdemir 1 collaboration

Kathleen Grabert 1 collaboration

Evi Wollscheid-Lengeling 1 collaboration

Barry Bradford 1 collaboration

Melanie Caruso 1 collaboration

Iveta Gazova 1 collaboration

Alejandra Sánchez 1 collaboration

Zofia M Lisowski 1 collaboration

Joana Alves 1 collaboration

Irene Molina-Gonzalez 1 collaboration

Hayk Davtyan 1 collaboration

Rebecca J Lodge 1 collaboration

James D Glover 1 collaboration

Robert Wallace 1 collaboration

David A D Munro 1 collaboration

Eyal David 1 collaboration

Ido Amit 1 collaboration

Véronique E Miron 1 collaboration

Stephen J Jenkins 1 collaboration

Giles E Hardingham 1 collaboration

Mathew Blurton-Jones 1 collaboration

Kim M Summers 1 collaboration

Peter Hohenstein 1 collaboration

Felipe Melo-Gonzalez 1 collaboration

Hana Kammoun 1 collaboration

Elza Evren 1 collaboration

Emma E Dutton 1 collaboration

Markella Papadopoulou 1 collaboration

Ceylan Tanes 1 collaboration

Fahmina Fardus-Reid 1 collaboration

Jonathan R Swann 1 collaboration

Kyle Bittinger 1 collaboration

Bruce A Vallance 1 collaboration

Tim Willinger 1 collaboration

David R Withers 1 collaboration

Matthew R Hepworth 1 collaboration