Quality of life in mothers and fathers of children treated for acute lymphoblastic leukaemia in Sweden, Finland and Denmark.
acute lymphoblastic leukaemia
cancer
childhood
parents
quality of life
questionnaire
Journal
British journal of haematology
ISSN: 1365-2141
Titre abrégé: Br J Haematol
Pays: England
ID NLM: 0372544
Informations de publication
Date de publication:
09 2022
09 2022
Historique:
revised:
24
06
2022
received:
19
04
2022
accepted:
25
06
2022
pubmed:
20
7
2022
medline:
14
9
2022
entrez:
19
7
2022
Statut:
ppublish
Résumé
Acute lymphoblastic leukaemia (ALL) has a high survival rate, but treatment is lengthy with risk of severe side-effects, which may also impact parents' health-related quality of life (HRQOL). We present data on 526 parents of 310 children treated for ALL according to the NOPHO ALL2008-protocol, in Sweden, Finland and Denmark. Parents were asked to complete the 36-Item Short Form Survey (SF-36) at least 6 months after end of treatment and data were compared with Norwegian reference data. Parental background factors were collected via a study-specific questionnaire. Participating parents scored significantly lower than the reference population on both physical and mental summary indexes, but only surpassed a minimal clinically important difference for the mental summary index (Mental Component Summary [MCS]). Mothers scored lower than fathers in the MCS and stopped working and took care of the affected child more often than the fathers. Higher mental HRQOL was associated with male gender and living in Finland or Denmark (compared to Sweden). Correlations within spouses in physical and mental scores were weak to moderate. In conclusion, ALL negatively affects parental HRQOL, especially the mental domains, even after treatment. Findings suggest that mothers are more affected than fathers and may require extra support.
Identifiants
pubmed: 35852790
doi: 10.1111/bjh.18350
pmc: PMC9543076
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1032-1040Informations de copyright
© 2022 The Authors. British Journal of Haematology published by British Society for Haematology and John Wiley & Sons Ltd.
Références
Qual Life Res. 2004 Feb;13(1):251-6
pubmed: 15058805
Eur J Haematol. 2016 Feb;96(2):160-9
pubmed: 25867866
Psychooncology. 2018 Aug;27(8):2031-2038
pubmed: 29772082
Qual Life Res. 2010 Sep;19(7):995-1005
pubmed: 20473638
Spine (Phila Pa 1976). 2018 Nov 1;43(21):E1260-E1266
pubmed: 29652783
Clin Orthop Relat Res. 2020 Sep;478(9):2148-2158
pubmed: 32568896
Health Qual Life Outcomes. 2017 Mar 14;15(1):51
pubmed: 28292292
Acta Oncol. 2018 Jul;57(7):950-957
pubmed: 29498559
J Psychosoc Oncol. 2022 Jan 12;:1-18
pubmed: 35016592
Psychooncology. 2008 May;17(5):448-59
pubmed: 17828715
Eur J Cancer Care (Engl). 2016 Jul;25(4):616-37
pubmed: 26354003
Br J Haematol. 2022 Sep;198(6):1032-1040
pubmed: 35852790
Asian Pac J Cancer Prev. 2020 Sep 01;21(9):2683-2688
pubmed: 32986369
Soc Sci Med. 1995 Nov;41(10):1349-58
pubmed: 8560302
Control Clin Trials. 1989 Dec;10(4):407-15
pubmed: 2691207
Support Care Cancer. 2007 Jul;15(7):807-18
pubmed: 17390154
J Patient Rep Outcomes. 2021 Aug 4;5(1):66
pubmed: 34347192
Spine J. 2007 Sep-Oct;7(5):541-6
pubmed: 17448732
Leukemia. 2018 Mar;32(3):606-615
pubmed: 28819280
J Clin Epidemiol. 1998 Nov;51(11):1189-202
pubmed: 9817137
Health Qual Life Outcomes. 2005 Apr 28;3:29
pubmed: 15860126
J Clin Oncol. 2008 Dec 20;26(36):5884-9
pubmed: 19029424
Cancer. 2018 Apr 1;124(7):1492-1500
pubmed: 29430634
J Psychosoc Oncol Res Pract. 2020 Jul 28;2(3):e024
pubmed: 32832904
Psychooncology. 2009 Sep;18(9):907-15
pubmed: 19319828
PLoS One. 2014 Jul 24;9(7):e103340
pubmed: 25058607
Qual Life Res. 2011 Oct;20(8):1261-9
pubmed: 21287280
Pediatr Blood Cancer. 2020 Oct;67(10):e28419
pubmed: 32798263
Bone Marrow Transplant. 2012 Jun;47(6):855-9
pubmed: 21946382
Med Care. 2003 May;41(5):582-92
pubmed: 12719681
Qual Life Res. 2005 May;14(4):1079-85
pubmed: 16041903
Psychooncology. 2015 Dec;24(12):1792-8
pubmed: 26042579
Clin Orthop Relat Res. 2017 Apr;475(4):929-932
pubmed: 28124297
J Clin Epidemiol. 1998 Nov;51(11):1149-58
pubmed: 9817132
Pediatr Blood Cancer. 2019 Jul;66(7):e27728
pubmed: 30916456
Child Health Care. 2016;45(3):303-322
pubmed: 27630380
J Pediatr Psychol. 2008 Aug;33(7):694-706
pubmed: 18287109