Cost-effectiveness of central automated unit dose dispensing with barcode-assisted medication administration in a hospital setting.

Barcode Cost-effectiveness Medication administration errors Medication errors Medication systems Patient safety

Journal

Research in social & administrative pharmacy : RSAP
ISSN: 1934-8150
Titre abrégé: Res Social Adm Pharm
Pays: United States
ID NLM: 101231974

Informations de publication

Date de publication:
11 2022
Historique:
received: 18 01 2022
revised: 14 05 2022
accepted: 10 07 2022
pubmed: 20 7 2022
medline: 28 9 2022
entrez: 19 7 2022
Statut: ppublish

Résumé

Central automated unit dose dispensing (cADD) with barcode-assisted medication administration (BCMA) has been shown to reduce medication administration errors (MAEs). Little is known about the cost-effectiveness of this intervention. To estimate the cost-effectiveness of cADD with BCMA compared to usual care. An economic evaluation was conducted alongside a prospective before-and-after effectiveness study in a Dutch university hospital. The primary effect measure was the difference between the rate of MAEs before and after implementation of cADD with BCMA, obtained by disguised observation in six clinical wards and subsequent extrapolation to the entire hospital. The cost-analysis was conducted from a hospital perspective with a 12-month incremental costing approach. The total costs covered the pharmaceutical service, nurse medication handling, wastage, and materials related to cADD. The primary outcome was the cost-effectiveness ratio expressed as costs per avoided MAE, obtained by dividing the annual incremental costs by the number of avoided MAEs. The secondary outcome was the cost-effectiveness ratio expressed as costs per avoided potentially harmful MAE (i.e. MAEs with the potential to cause harm). The intervention was associated with an absolute MAE reduction of 4.5% and a reduction of 2.7% for potentially harmful MAEs. Based on 2,260,870 administered medications in the entire hospital annually, a total of 102,210 MAEs and 59,830 potentially harmful MAEs were estimated to be avoided. The intervention was associated with an increased incremental cost of €1,808,600 annually. The cost-effectiveness ratio was €17.69 per avoided MAE and €30.23 per avoided potentially harmful MAE. The implementation of cADD with BCMA was associated with a reduced rate of medication errors, including harmful ones, at higher overall costs. The costs per avoided error are relatively low, and therefore, this intervention could be an important strategy to improve patient safety in hospitals.

Sections du résumé

BACKGROUND
Central automated unit dose dispensing (cADD) with barcode-assisted medication administration (BCMA) has been shown to reduce medication administration errors (MAEs). Little is known about the cost-effectiveness of this intervention.
OBJECTIVE
To estimate the cost-effectiveness of cADD with BCMA compared to usual care.
METHODS
An economic evaluation was conducted alongside a prospective before-and-after effectiveness study in a Dutch university hospital. The primary effect measure was the difference between the rate of MAEs before and after implementation of cADD with BCMA, obtained by disguised observation in six clinical wards and subsequent extrapolation to the entire hospital. The cost-analysis was conducted from a hospital perspective with a 12-month incremental costing approach. The total costs covered the pharmaceutical service, nurse medication handling, wastage, and materials related to cADD. The primary outcome was the cost-effectiveness ratio expressed as costs per avoided MAE, obtained by dividing the annual incremental costs by the number of avoided MAEs. The secondary outcome was the cost-effectiveness ratio expressed as costs per avoided potentially harmful MAE (i.e. MAEs with the potential to cause harm).
RESULTS
The intervention was associated with an absolute MAE reduction of 4.5% and a reduction of 2.7% for potentially harmful MAEs. Based on 2,260,870 administered medications in the entire hospital annually, a total of 102,210 MAEs and 59,830 potentially harmful MAEs were estimated to be avoided. The intervention was associated with an increased incremental cost of €1,808,600 annually. The cost-effectiveness ratio was €17.69 per avoided MAE and €30.23 per avoided potentially harmful MAE.
CONCLUSIONS
The implementation of cADD with BCMA was associated with a reduced rate of medication errors, including harmful ones, at higher overall costs. The costs per avoided error are relatively low, and therefore, this intervention could be an important strategy to improve patient safety in hospitals.

Identifiants

pubmed: 35853809
pii: S1551-7411(22)00210-8
doi: 10.1016/j.sapharm.2022.07.006
pii:
doi:

Substances chimiques

B-Cell Maturation Antigen 0
Pharmaceutical Preparations 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

3980-3987

Informations de copyright

Copyright © 2022 The Authors. Published by Elsevier Inc. All rights reserved.

Auteurs

Janique Gabriëlle Jessurun (JG)

Department of Hospital Pharmacy, Erasmus MC, University Medical Center Rotterdam, Rotterdam, P.O. Box 2040, 3000 CA, the Netherlands. Electronic address: j.g.jessurun@erasmusmc.nl.

Nicole Geertruida Maria Hunfeld (NGM)

Department of Hospital Pharmacy, Erasmus MC, University Medical Center Rotterdam, Rotterdam, P.O. Box 2040, 3000 CA, the Netherlands; Department of Intensive Care, Erasmus MC, University Medical Center Rotterdam, Rotterdam, P.O. Box 2040, 3000 CA, the Netherlands. Electronic address: n.hunfeld@erasmusmc.nl.

Monique van Dijk (M)

Department of Internal Medicine, Section of Nursing Science, Erasmus MC, University Medical Center Rotterdam, Rotterdam, P.O. Box 2040, 3000 CA, the Netherlands. Electronic address: m.vandijk3@erasmusmc.nl.

Patricia Maria Lucia Adriana van den Bemt (PMLA)

Department of Hospital Pharmacy, Erasmus MC, University Medical Center Rotterdam, Rotterdam, P.O. Box 2040, 3000 CA, the Netherlands; Department of Clinical Pharmacy and Pharmacology, University Medical Center Groningen, Groningen, P.O. Box 30.001, 9700 RB, the Netherlands. Electronic address: p.m.l.a.van.den.bemt@umcg.nl.

Suzanne Polinder (S)

Department of Public Health, Erasmus MC, University Medical Center Rotterdam, Rotterdam, P.O. Box 2040, 3000 CA, the Netherlands. Electronic address: s.polinder@erasmusmc.nl.

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