Organizing structural principles of the IL-17 ligand-receptor axis.

Cryoelectron Microscopy Interleukin-17 / chemistry Ligands Protein Domains Protein Multimerization Receptors, Interleukin-17 / chemistry Signal Transduction Single Molecule Imaging

Journal

Nature
ISSN: 1476-4687
Titre abrégé: Nature
Pays: England
ID NLM: 0410462

Informations de publication

Date de publication:
09 2022
Historique:
received: 07 05 2022
accepted: 15 07 2022
pubmed: 22 7 2022
medline: 20 9 2022
entrez: 21 7 2022
Statut: ppublish

Résumé

The IL-17 family of cytokines and receptors have central roles in host defence against infection and development of inflammatory diseases

Identifiants

DOI: 10.1038/s41586-022-05116-y PMID: 35863378 PMC: PMC9477748
pubmed: 35863378
doi: 10.1038/s41586-022-05116-y
pii: 10.1038/s41586-022-05116-y
pmc: PMC9477748
doi:

Substances chimiques

Interleukin-17 0
Ligands 0
Receptors, Interleukin-17 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

622-629

Subventions

Organisme : NIAID NIH HHS
ID : R01 AI051321
Pays : United States
Organisme : NIAID NIH HHS
ID : T32 AI007290
Pays : United States
Organisme : NIAMS NIH HHS
ID : T32 AR050942
Pays : United States
Organisme : Howard Hughes Medical Institute
Pays : United States

Informations de copyright

© 2022. The Author(s).

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Auteurs

Steven C Wilson (SC)

Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA, USA.
Department of Structural Biology, Stanford University School of Medicine, Stanford, CA, USA.
ORCID: 0000-0002-7382-3388

Nathanael A Caveney (NA)

Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA, USA.
Department of Structural Biology, Stanford University School of Medicine, Stanford, CA, USA.
ORCID: 0000-0003-4828-3479

Michelle Yen (M)

Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA, USA.
Department of Structural Biology, Stanford University School of Medicine, Stanford, CA, USA.

Christoph Pollmann (C)

Divison of Biophysics, Department of Biology, University of Osnabrück, Osnabrück, Germany.

Xinyu Xiang (X)

Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA, USA.
Department of Structural Biology, Stanford University School of Medicine, Stanford, CA, USA.
ORCID: 0000-0002-8358-2960

Kevin M Jude (KM)

Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA, USA.
Department of Structural Biology, Stanford University School of Medicine, Stanford, CA, USA.
Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA, USA.
ORCID: 0000-0002-3675-5136

Maximillian Hafer (M)

Divison of Biophysics, Department of Biology, University of Osnabrück, Osnabrück, Germany.

Naotaka Tsutsumi (N)

Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA, USA.
Department of Structural Biology, Stanford University School of Medicine, Stanford, CA, USA.
Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA, USA.
ORCID: 0000-0002-3617-7145

Jacob Piehler (J)

Divison of Biophysics, Department of Biology, University of Osnabrück, Osnabrück, Germany.
ORCID: 0000-0002-2143-2270

K Christopher Garcia (KC)

Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA, USA. kcgarcia@stanford.edu.
Department of Structural Biology, Stanford University School of Medicine, Stanford, CA, USA. kcgarcia@stanford.edu.
Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA, USA. kcgarcia@stanford.edu.
ORCID: 0000-0001-9273-0278

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Classifications MeSH

questionsmedicales.fr › Techniques d'investigation › Microscopie électronique › Cryomicroscopie électronique › Organizing structural principles of the IL-17...
questionsmedicales.fr › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Cytokines › Interleukines › Interleukine-17 › Organizing structural principles of the IL-17...
questionsmedicales.fr › Actions chimiques et utilisations › Utilisations spécialisées de produits chimiques › Produits chimiques de laboratoire › Ligands › Organizing structural principles of the IL-17...
questionsmedicales.fr › Phénomènes chimiques › Phénomènes biochimiques › Conformation moléculaire › Conformation des protéines › Structure tertiaire des protéines › Domaines protéiques › Organizing structural principles of the IL-17...
questionsmedicales.fr › Phénomènes chimiques › Phénomènes biochimiques › Multimérisation de protéines › Organizing structural principles of the IL-17...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs immunologiques › Récepteurs aux cytokines › Récepteurs aux interleukines › Récepteurs à l'interleukine-17 › Organizing structural principles of the IL-17...
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Transduction du signal › Organizing structural principles of the IL-17...
questionsmedicales.fr › Techniques d'investigation › Techniques de sonde moléculaire › Imagerie moléculaire › Imagerie de molécules uniques › Organizing structural principles of the IL-17...