Acute kidney injury in dogs following ingestion of cream of tartar and tamarinds and the connection to tartaric acid as the proposed toxic principle in grapes and raisins.
AKI
Vitis vinifera ingestion
canine
nephrotoxins
Journal
Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)
ISSN: 1476-4431
Titre abrégé: J Vet Emerg Crit Care (San Antonio)
Pays: United States
ID NLM: 101152804
Informations de publication
Date de publication:
Nov 2022
Nov 2022
Historique:
revised:
04
03
2022
received:
09
09
2021
accepted:
12
03
2022
pubmed:
24
7
2022
medline:
19
11
2022
entrez:
23
7
2022
Statut:
ppublish
Résumé
To (1) describe exposure history, clinical signs, treatment, and diagnostic findings in 4 dogs following ingestion of tamarinds, and in 2 dogs following ingestion of cream of tartar, and (2) discuss tartaric acid, the common denominator, as the proposed toxic principle in tamarinds and grapes. Reports in which dogs developed acute kidney injury following ingestion of cream of tartar or tamarinds were identified from the ASPCA Animal Poison Control Center electronic database. In these cases, decontamination was not performed, and treatments were delayed. Despite IV fluids and symptomatic and supportive care, 2 of the dogs became anuric and 1 became oliguric. Four dogs were euthanized, and the outcome is unknown for 2 of the dogs. Necropsies were performed on 3 of the dogs. Clinical signs, laboratory findings, and histopathologic lesions were similar to those reported in grape and raisin toxicosis. Acute kidney injury may develop following ingestion of cream of tartar or tamarinds in dogs. Connecting these reports with findings in grape and raisin toxicosis and the sensitivity to tartaric acid in dogs, tartaric acid is identified as the likely toxic component in grapes and tamarinds.
Substances chimiques
tartaric acid
W4888I119H
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
812-816Informations de copyright
© Veterinary Emergency and Critical Care Society 2022.
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