Handgrip strength to screen early-onset sarcopenia in heart failure.
Accuracy
Chronic heart failure
Handgrip strength
Sarcopenia
Journal
Clinical nutrition ESPEN
ISSN: 2405-4577
Titre abrégé: Clin Nutr ESPEN
Pays: England
ID NLM: 101654592
Informations de publication
Date de publication:
08 2022
08 2022
Historique:
received:
16
12
2021
revised:
09
05
2022
accepted:
26
05
2022
entrez:
25
7
2022
pubmed:
26
7
2022
medline:
27
7
2022
Statut:
ppublish
Résumé
Sarcopenia in heart failure (HF) is associated with severe outcomes, increased mortality, and high healthcare cost burden. Systematic muscle screening in patients with chronic HF would improve quality and appropriateness of care. Here we tested handgrip strength (HGS) as a screening tool for sarcopenia in patients with chronic HF, using the EWGSOP 2010 and 2019 reference-standard definitions of sarcopenia. HF inpatients, aged 65 years old or above, were prospectively included between November 2014 and September 2018, and relevant sociodemographic, anthropometric and HF characterization data was collected. The accuracy of HGS as a screening test for sarcopenia was assessed by gender using area under the receiver operating characteristic (ROC) curves (AUC). The population consisted of 118 older patients (age: 78.9 yrs; BMI: 26.6 kg/m HGS can be used as a valid tool to screen for sarcopenia in older (≥65 yrs) patients with chronic HF. NCT03153774.
Sections du résumé
BACKGROUND & AIMS
Sarcopenia in heart failure (HF) is associated with severe outcomes, increased mortality, and high healthcare cost burden. Systematic muscle screening in patients with chronic HF would improve quality and appropriateness of care. Here we tested handgrip strength (HGS) as a screening tool for sarcopenia in patients with chronic HF, using the EWGSOP 2010 and 2019 reference-standard definitions of sarcopenia.
METHODS
HF inpatients, aged 65 years old or above, were prospectively included between November 2014 and September 2018, and relevant sociodemographic, anthropometric and HF characterization data was collected. The accuracy of HGS as a screening test for sarcopenia was assessed by gender using area under the receiver operating characteristic (ROC) curves (AUC).
RESULTS
The population consisted of 118 older patients (age: 78.9 yrs; BMI: 26.6 kg/m
CONCLUSIONS
HGS can be used as a valid tool to screen for sarcopenia in older (≥65 yrs) patients with chronic HF.
CLINICAL TRIAL REGISTRATION
NCT03153774.
Identifiants
pubmed: 35871922
pii: S2405-4577(22)00284-4
doi: 10.1016/j.clnesp.2022.05.019
pii:
doi:
Banques de données
ClinicalTrials.gov
['NCT03153774']
Types de publication
Clinical Study
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
183-190Informations de copyright
Copyright © 2022 European Society for Clinical Nutrition and Metabolism. Published by Elsevier Ltd. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of competing interest The authors have no conflicts of interest.