Influence of Water on Amorphous Lidocaine.

Calorimetry, Differential Scanning Glass Lidocaine Temperature Transition Temperature
anti-plasticizing effect co-amorphous glass transition lidocaine molecular interaction

Journal

Molecular pharmaceutics
ISSN: 1543-8392
Titre abrégé: Mol Pharm
Pays: United States
ID NLM: 101197791

Informations de publication

Date de publication:
05 09 2022
Historique:
pubmed: 26 7 2022
medline: 9 9 2022
entrez: 25 7 2022
Statut: ppublish

Résumé

Water is generally regarded as a universal plasticizer of amorphous drugs or amorphous drug-containing systems. A decrease in glass-transition temperature (

Identifiants

DOI: 10.1021/acs.molpharmaceut.2c00339 PMID: 35876141
pubmed: 35876141
doi: 10.1021/acs.molpharmaceut.2c00339
doi:

Substances chimiques

Lidocaine 98PI200987

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

3199-3205

Auteurs

Xiaoyue Xu (X)

Department of Pharmacy, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen, Denmark.

Holger Grohganz (H)

Department of Pharmacy, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen, Denmark.
ORCID: 0000-0002-0482-1397

Thomas Rades (T)

Department of Pharmacy, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen, Denmark.
ORCID: 0000-0002-7521-6020

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Classifications MeSH

questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Analyse thermique différentielle › Calorimétrie différentielle à balayage › Influence of Water on Amorphous Lidocaine.
questionsmedicales.fr › Technologie, industrie et agriculture › Produits manufacturés › Verre › Influence of Water on Amorphous Lidocaine.
questionsmedicales.fr › Composés chimiques organiques › Amines › Dérivés de l'aniline › Anilides › Acétanilides › Lidocaïne › Influence of Water on Amorphous Lidocaine.
questionsmedicales.fr › Environnement et santé publique › Environnement › Concepts météorologiques › Atmosphère › Temps (météorologie) › Température › Influence of Water on Amorphous Lidocaine.
questionsmedicales.fr › Phénomènes physiques › Thermodynamique › Température de transition › Influence of Water on Amorphous Lidocaine.