Intestinal Inflammation Reversibly Alters the Microbiota to Drive Susceptibility to Clostridioides difficile Colonization in a Mouse Model of Colitis.


Journal

mBio
ISSN: 2150-7511
Titre abrégé: mBio
Pays: United States
ID NLM: 101519231

Informations de publication

Date de publication:
30 08 2022
Historique:
pubmed: 29 7 2022
medline: 3 9 2022
entrez: 28 7 2022
Statut: ppublish

Résumé

Susceptibility to Clostridioides difficile infection (CDI) typically follows the administration of antibiotics. Patients with inflammatory bowel disease (IBD) have increased incidence of CDI, even in the absence of antibiotic treatment. However, the mechanisms underlying this susceptibility are not well understood. To explore the intersection between CDI and IBD, we recently described a mouse model where colitis triggered by the murine gut bacterium, Helicobacter hepaticus, in IL-10

Identifiants

pubmed: 35900107
doi: 10.1128/mbio.01904-22
pmc: PMC9426610
doi:

Substances chimiques

Anti-Bacterial Agents 0
Antibodies, Monoclonal 0

Types de publication

Journal Article Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

e0190422

Subventions

Organisme : NIAID NIH HHS
ID : T32 AI007528
Pays : United States
Organisme : NIAID NIH HHS
ID : U01 AI124255
Pays : United States
Organisme : NIAID NIH HHS
ID : U19 AI090871
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR002240
Pays : United States

Références

Gut Microbes. 2011 Nov-Dec;2(6):326-34
pubmed: 22198617
Infect Immun. 1997 Aug;65(8):3126-31
pubmed: 9234764
mBio. 2020 Jun 9;11(3):
pubmed: 32518182
Microbes Infect. 2016 Jan;18(1):30-8
pubmed: 26383014
Dis Colon Rectum. 2009 Jan;52(1):40-5
pubmed: 19273954
Infect Immun. 2015 Mar;83(3):934-41
pubmed: 25534943
mSphere. 2016 Jan 06;1(1):
pubmed: 27239562
J Crohns Colitis. 2009 Feb;3(1):4-7
pubmed: 21172241
Gut. 2013 Apr;62(4):531-9
pubmed: 22993202
Appl Environ Microbiol. 2013 Sep;79(17):5112-20
pubmed: 23793624
mSphere. 2021 May 5;6(3):
pubmed: 33952668
J Open Source Softw. 2021;6(61):
pubmed: 34414351
mSystems. 2022 Apr 26;7(2):e0138321
pubmed: 35354321
J Dig Dis. 2019 Sep;20(9):460-466
pubmed: 31278840
Infect Immun. 2015 Oct;83(10):3838-46
pubmed: 26169276
J Exp Med. 2006 Oct 30;203(11):2485-94
pubmed: 17030948
Clin Gastroenterol Hepatol. 2007 Mar;5(3):339-44
pubmed: 17368233
Antimicrob Agents Chemother. 2015 Aug;59(8):4533-43
pubmed: 25987626
J Hepatol. 2013 May;58(5):949-55
pubmed: 23333527
Nat Commun. 2021 Jan 19;12(1):462
pubmed: 33469019
Appl Environ Microbiol. 2009 Dec;75(23):7537-41
pubmed: 19801464
PLoS One. 2012;7(2):e30126
pubmed: 22319561
Gut Microbes. 2011 May-Jun;2(3):145-58
pubmed: 21804357
Sci Rep. 2016 Jul 15;6:29791
pubmed: 27417996
mBio. 2015 Jul 14;6(4):e00974
pubmed: 26173701
Sci Rep. 2019 Jun 20;9(1):8872
pubmed: 31222159
Infect Immun. 2020 May 20;88(6):
pubmed: 32284366
Gastroenterology. 2008 Dec;135(6):1984-92
pubmed: 18848941
PLoS Pathog. 2021 Oct 19;17(10):e1010015
pubmed: 34665847
Trends Microbiol. 2012 Jul;20(7):313-9
pubmed: 22595318
Anaerobe. 2018 Oct;53:64-73
pubmed: 29654837
Infect Immun. 2006 Aug;74(8):4496-504
pubmed: 16861635
J Infect Dis. 2017 Apr 1;215(7):1117-1123
pubmed: 28498996
Nat Microbiol. 2019 Feb;4(2):293-305
pubmed: 30531976
mBio. 2021 Jun 29;12(3):e0273320
pubmed: 34126769
PLoS Pathog. 2021 Oct 21;17(10):e1009959
pubmed: 34673840
Nat Microbiol. 2018 Jun;3(6):662-669
pubmed: 29686297
Infect Immun. 2004 May;72(5):2521-7
pubmed: 15102759
J AOAC Int. 2011 Mar-Apr;94(2):618-26
pubmed: 21563698
J Exp Med. 2003 Jan 6;197(1):111-9
pubmed: 12515818
mBio. 2014 May 06;5(3):e01021-14
pubmed: 24803517
Antimicrob Agents Chemother. 2012 Aug;56(8):4103-11
pubmed: 22585229
J Infect Dis. 2021 Jun 16;223(12 Suppl 2):S194-S200
pubmed: 33326565
Gastroenterology. 2017 Feb;152(2):327-339.e4
pubmed: 27769810
J Clin Microbiol. 2014 Feb;52(2):398-406
pubmed: 24478468
Genome Biol. 2011 Jun 24;12(6):R60
pubmed: 21702898
Infect Immun. 2009 Sep;77(9):3661-9
pubmed: 19564382
Nat Rev Gastroenterol Hepatol. 2017 Oct;14(10):573-584
pubmed: 28743984
Anaerobe. 2013 Dec;24:94-7
pubmed: 24076318
Nat Commun. 2014;5:3114
pubmed: 24445449
Inflamm Bowel Dis. 2018 Jul 12;24(8):1849-1856
pubmed: 29722832
mSphere. 2017 Mar 8;2(2):
pubmed: 28289728
J Infect Dis. 2015 Nov 15;212(10):1656-65
pubmed: 25920320
Nat Med. 2020 Apr;26(4):608-617
pubmed: 32066975
Nat Med. 2019 Feb;25(2):323-336
pubmed: 30664783
Infect Immun. 2001 Jul;69(7):4232-41
pubmed: 11401959
Microbiome. 2013 May 10;1(1):15
pubmed: 24450737
Scand J Gastroenterol. 1996 Jul;31(7):688-93
pubmed: 8819219
PLoS One. 2015 Mar 04;10(3):e0118432
pubmed: 25738806
J Clin Microbiol. 2013 Sep;51(9):2884-92
pubmed: 23804381
Gastroenterology. 2014 May;146(6):1547-53
pubmed: 24503131
Pathogens. 2019 Aug 13;8(3):
pubmed: 31412603
Infect Immun. 2012 Nov;80(11):3786-94
pubmed: 22890996
Bioinformatics. 2010 May 15;26(10):1340-7
pubmed: 20385727
Bioinformatics. 2011 Aug 15;27(16):2194-200
pubmed: 21700674

Auteurs

Madeline R Barron (MR)

Department of Microbiology & Immunology, University of Michigan Medical Schoolgrid.471406.0, Ann Arbor, Michigan, USA.

Kelly L Sovacool (KL)

Department of Computational Medicine & Bioinformatics, University of Michigan Medical Schoolgrid.471406.0, Ann Arbor Michigan, USA.

Lisa Abernathy-Close (L)

Division of Rheumatology, Department of Internal Medicine, University of Michigan Medical Schoolgrid.471406.0, Ann Arbor, Michigan, USA.

Kimberly C Vendrov (KC)

Division of Infectious Diseases, Department of Internal Medicine, University of Michigan Medical Schoolgrid.471406.0, Ann Arbor, Michigan, USA.

Alexandra K Standke (AK)

Division of Infectious Diseases, Department of Internal Medicine, University of Michigan Medical Schoolgrid.471406.0, Ann Arbor, Michigan, USA.

Ingrid L Bergin (IL)

The Unit for Laboratory Animal Medicine, University of Michigan Medical Schoolgrid.471406.0, Ann Arbor, Michigan, USA.

Patrick D Schloss (PD)

Department of Microbiology & Immunology, University of Michigan Medical Schoolgrid.471406.0, Ann Arbor, Michigan, USA.

Vincent B Young (VB)

Department of Microbiology & Immunology, University of Michigan Medical Schoolgrid.471406.0, Ann Arbor, Michigan, USA.
Division of Infectious Diseases, Department of Internal Medicine, University of Michigan Medical Schoolgrid.471406.0, Ann Arbor, Michigan, USA.

Articles similaires

Vancomycin-associated DRESS demonstrates delay in AST abnormalities.

Ahmed Hussein, Kateri L Schoettinger, Jourdan Hydol-Smith et al.
1.00
Humans Drug Hypersensitivity Syndrome Vancomycin Female Male
Robotic Surgical Procedures Animals Humans Telemedicine Models, Animal

Odour generalisation and detection dog training.

Lyn Caldicott, Thomas W Pike, Helen E Zulch et al.
1.00
Animals Odorants Dogs Generalization, Psychological Smell
C-Reactive Protein Humans Biomarkers Inflammation

Classifications MeSH