Gata6
Journal
Nature communications
ISSN: 2041-1723
Titre abrégé: Nat Commun
Pays: England
ID NLM: 101528555
Informations de publication
Date de publication:
29 07 2022
29 07 2022
Historique:
received:
09
09
2020
accepted:
18
07
2022
entrez:
29
7
2022
pubmed:
30
7
2022
medline:
3
8
2022
Statut:
epublish
Résumé
Emerging evidence suggests that resident macrophages within tissues are enablers of tumor growth. However, a second population of resident macrophages surrounds all visceral organs within the cavities and nothing is known about these GATA6
Identifiants
pubmed: 35906202
doi: 10.1038/s41467-022-32080-y
pii: 10.1038/s41467-022-32080-y
pmc: PMC9338095
doi:
Substances chimiques
B7-H1 Antigen
0
GATA6 Transcription Factor
0
GATA6 protein, human
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
4406Subventions
Organisme : NIAID NIH HHS
ID : P01 AI056299
Pays : United States
Informations de copyright
© 2022. The Author(s).
Références
Mantovani, A., Marchesi, F., Malesci, A., Laghi, L. & Allavena, P. Tumour-associated macrophages as treatment targets in oncology. Nat. Rev. Clin. Oncol. 14, 399–416 (2017).
pubmed: 28117416
pmcid: 5480600
doi: 10.1038/nrclinonc.2016.217
Noy, R. & Pollard, J. W. Tumor-associated macrophages: from mechanisms to therapy. Immunity 41, 49–61 (2014).
pubmed: 25035953
pmcid: 4137410
doi: 10.1016/j.immuni.2014.06.010
Zhang, Y., Zhao, Y., Li, Q. & Wang, Y. Macrophages, as a promising strategy to targeted treatment for colorectal cancer metastasis in tumor immune microenvironment. Front. Immunol. 12, 685978 (2021).
Movahedi, K. et al. Different tumor microenvironments contain functionally distinct subsets of macrophages derived from Ly6C(high) monocytes. Cancer Res. 70, 5728–5739 (2010).
pubmed: 20570887
doi: 10.1158/0008-5472.CAN-09-4672
Franklin, R. A. et al. The cellular and molecular origin of tumor-associated macrophages. Science 344, 921–925 (2014).
pubmed: 24812208
pmcid: 4204732
doi: 10.1126/science.1252510
Qian, B. Z. et al. CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis. Nature 475, 222–225 (2011).
pubmed: 21654748
pmcid: 3208506
doi: 10.1038/nature10138
Mowat, A. M., Scott, C. L. & Bain, C. C. Barrier-tissue macrophages: functional adaptation to environmental challenges. Nat. Med. 23, 1258–1270 (2017).
pubmed: 29117177
doi: 10.1038/nm.4430
Müller, A., Brandenburg, S., Turkowski, K., Müller, S. & Vajkoczy, P. Resident microglia, and not peripheral macrophages, are the main source of brain tumor mononuclear cells. Int J. Cancer 137, 278–288 (2015).
pubmed: 25477239
doi: 10.1002/ijc.29379
Zhu, Y. et al. Tissue-resident macrophages in pancreatic ductal adenocarcinoma originate from embryonic hematopoiesis and promote tumor progression. Immunity 47, 597 (2017).
pubmed: 28930665
doi: 10.1016/j.immuni.2017.08.018
Soncin, I. et al. The tumour microenvironment creates a niche for the self-renewal of tumour-promoting macrophages in colon adenoma. Nat. Commun. 9, 582 (2018).
pubmed: 29422500
pmcid: 5805689
doi: 10.1038/s41467-018-02834-8
Ghosn, E. E. et al. Two physically, functionally, and developmentally distinct peritoneal macrophage subsets. Proc. Natl Acad. Sci. USA 107, 2568–2573 (2010).
pubmed: 20133793
pmcid: 2823920
doi: 10.1073/pnas.0915000107
Zhang, N. et al. Expression of factor V by resident macrophages boosts host defense in the peritoneal cavity. J. Exp. Med. 216, 1291–1300 (2019).
pubmed: 31048328
pmcid: 6547866
doi: 10.1084/jem.20182024
Buechler, M. B. et al. A stromal niche defined by expression of the transcription factor WT1 mediates programming and homeostasis of cavity-resident macrophages. Immunity 51, 119–130 (2019). e115.
pubmed: 31231034
pmcid: 6814267
doi: 10.1016/j.immuni.2019.05.010
Deniset, J. F. et al. Gata6+ pericardial cavity macrophages relocate to the injured heart and prevent cardiac fibrosis. Immunity 51, 131–140 (2019). e135.
pubmed: 31315031
pmcid: 7574643
doi: 10.1016/j.immuni.2019.06.010
Wang, J. & Kubes, P. A reservoir of mature cavity macrophages that can rapidly invade visceral organs to affect tissue repair. Cell 165, 668–678 (2016).
pubmed: 27062926
doi: 10.1016/j.cell.2016.03.009
Nishino, M., Ramaiya, N. H., Hatabu, H. & Hodi, F. S. Monitoring immune-checkpoint blockade: response evaluation and biomarker development. Nat. Rev. Clin. Oncol. 14, 655–668 (2017).
pubmed: 28653677
pmcid: 5650537
doi: 10.1038/nrclinonc.2017.88
Gordon, S. R. et al. PD-1 expression by tumour-associated macrophages inhibits phagocytosis and tumour immunity. Nature 545, 495–499 (2017).
pubmed: 28514441
pmcid: 5931375
doi: 10.1038/nature22396
Kortlever, R. M. et al. Myc cooperates with Ras by programming inflammation and immune suppression. Cell 171, 1301–1315.e1314 (2017).
pubmed: 29195074
pmcid: 5720393
doi: 10.1016/j.cell.2017.11.013
Perry, C. J. et al. Myeloid-targeted immunotherapies act in synergy to induce inflammation and antitumor immunity. J. Exp. Med. 215, 877–893 (2018).
pubmed: 29436395
pmcid: 5839759
doi: 10.1084/jem.20171435
Yang, M., McKay, D., Pollard, J. W. & Lewis, C. E. Diverse functions of macrophages in different tumor microenvironments. Cancer Res 78, 5492–5503 (2018).
pubmed: 30206177
pmcid: 6171744
doi: 10.1158/0008-5472.CAN-18-1367
Haderk, F. et al. Tumor-derived exosomes modulate PD-L1 expression in monocytes. Sci. Immunol. 2, eaah5509 (2017).
Hegde, P. S. & Chen, D. S. Top 10 challenges in cancer immunotherapy. Immunity 52, 17–35 (2020).
pubmed: 31940268
doi: 10.1016/j.immuni.2019.12.011
Bilen, M. A. et al. Sites of metastasis and association with clinical outcome in advanced stage cancer patients treated with immunotherapy. BMC Cancer 19, 857 (2019).
pubmed: 31464611
pmcid: 6716879
doi: 10.1186/s12885-019-6073-7
Okabe, Y. & Medzhitov, R. Tissue-specific signals control reversible program of localization and functional polarization of macrophages. Cell 157, 832–844 (2014).
pubmed: 24792964
pmcid: 4137874
doi: 10.1016/j.cell.2014.04.016
Zarour, L. R. et al. Colorectal cancer liver metastasis: evolving paradigms and future directions. Cell Mol. Gastroenterol. Hepatol. 3, 163–173 (2017).
pubmed: 28275683
pmcid: 5331831
doi: 10.1016/j.jcmgh.2017.01.006
Otten, M. A. et al. Experimental antibody therapy of liver metastases reveals functional redundancy between FcγRI and FcγRIV. J. Immunol. 181, 6829–6836 (2008).
pubmed: 18981101
doi: 10.4049/jimmunol.181.10.6829
Babes, L., Shim, R. & Kubes, P. Imaging α-GalCer-activated iNKT cells in a hepatic metastatic environment. Cancer Immunol. Res. 10, 12–25 (2022).
pubmed: 34785505
doi: 10.1158/2326-6066.CIR-21-0445
Neupane, A. S. et al. Patrolling alveolar macrophages conceal bacteria from the immune system to maintain homeostasis. Cell 183, 110–125 (2020). e111.
pubmed: 32888431
doi: 10.1016/j.cell.2020.08.020
Zindel, J. et al. Primordial GATA6 macrophages function as extravascular platelets in sterile injury. Science 371, eabe0595 (2021).
pubmed: 33674464
doi: 10.1126/science.abe0595
Herrick, S. E. & Mutsaers, S. E. Mesothelial progenitor cells and their potential in tissue engineering. Int. J. Biochem. Cell Biol. 36, 621–642 (2004).
pubmed: 15010328
doi: 10.1016/j.biocel.2003.11.002
Rosas, M. et al. The transcription factor Gata6 links tissue macrophage phenotype and proliferative renewal. Science 344, 645–648 (2014).
pubmed: 24762537
pmcid: 4185421
doi: 10.1126/science.1251414
Lai, C. P. et al. Visualization and tracking of tumour extracellular vesicle delivery and RNA translation using multiplexed reporters. Nat. Commun. 6, 7029 (2015).
pubmed: 25967391
doi: 10.1038/ncomms8029
Fiegle, E. et al. Dual CTLA-4 and PD-L1 blockade inhibits tumor growth and liver metastasis in a highly aggressive orthotopic mouse model of colon cancer. Neoplasia 21, 932–944 (2019).
pubmed: 31412307
pmcid: 6700499
doi: 10.1016/j.neo.2019.07.006
Ghiringhelli, F. & Fumet, J. D. Is there a place for immunotherapy for metastatic microsatellite stable colorectal cancer? Front Immunol. 10, 1816 (2019).
pubmed: 31447840
pmcid: 6691024
doi: 10.3389/fimmu.2019.01816
Liu, Y. & Cao, X. The origin and function of tumor-associated macrophages. Cell Mol. Immunol. 12, 1–4 (2015).
pubmed: 25220733
doi: 10.1038/cmi.2014.83
Cortese, N. et al. Macrophages in colorectal cancer liver metastases. Cancers (Basel) 11, 633 (2019).
Kim, H. J., Lee, D. H., Lim, J. W., Ko, Y. T. & Kim, K. W. Exophytic benign and malignant hepatic tumors: CT imaging features. Korean J. Radiol. 9, 67–75 (2008).
pubmed: 18253078
pmcid: 2627168
doi: 10.3348/kjr.2008.9.1.67
Lee, J. W. et al. Hepatic capsular and subcapsular pathologic conditions: demonstration with CT and MR imaging. Radiographics 28, 1307–1323 (2008).
pubmed: 18794308
doi: 10.1148/rg.285075089
Davidowitz, R. A. et al. Mesenchymal gene program-expressing ovarian cancer spheroids exhibit enhanced mesothelial clearance. J. Clin. Invest. 124, 2611–2625 (2014).
pubmed: 24762435
pmcid: 4038562
doi: 10.1172/JCI69815
Li, P. K.-T. et al. ISPD peritonitis recommendations: 2016 update on prevention and treatment. Perit. Dialysis Int. 36, 481–508 (2016).
doi: 10.3747/pdi.2016.00078
Morimoto, K. et al. The impact of intraperitoneal antibiotic administration in patients with peritoneal dialysis-related peritonitis: systematic review and meta-analysis. Ren. Replacement Ther. 6, 1–6 (2020).
Rocha, F. G. & Helton, W. S. Resectability of colorectal liver metastases: an evolving definition. HPB (Oxford) 14, 283–284 (2012).
doi: 10.1111/j.1477-2574.2012.00451.x
Venkat, S. R., Mohan, P. P. & Gandhi, R. T. Colorectal liver metastasis: overview of treatment paradigm highlighting the role of ablation. AJR Am. J. Roentgenol. 210, 883–890 (2018).
pubmed: 29446675
doi: 10.2214/AJR.17.18574
van Amerongen, M. J., Jenniskens, S. F. M., van den Boezem, P. B., Fütterer, J. J. & de Wilt, J. H. W. Radiofrequency ablation compared to surgical resection for curative treatment of patients with colorectal liver metastases—a meta-analysis. HPB (Oxford) 19, 749–756 (2017).
doi: 10.1016/j.hpb.2017.05.011
Wang, L. J. et al. Radiofrequency ablation versus resection for technically resectable colorectal liver metastasis: a propensity score analysis. World J. Surg. Oncol. 16, 207 (2018).
pubmed: 30322402
pmcid: 6190664
doi: 10.1186/s12957-018-1494-3
Sucandy, I. et al. Longterm survival outcomes of patients undergoing treatment with radiofrequency ablation for hepatocellular carcinoma and metastatic colorectal cancer liver tumors. HPB (Oxford) 18, 756–763 (2016).
doi: 10.1016/j.hpb.2016.06.010
Benhaim, L. et al. Radiofrequency ablation for colorectal cancer liver metastases initially greater than 25 mm but downsized by neo-adjuvant chemotherapy is associated with increased rate of local tumor progression. HPB (Oxford) 20, 76–82 (2018).
doi: 10.1016/j.hpb.2017.08.023
Takahashi, H., Akyuz, M., Aksoy, E., Karabulut, K. & Berber, E. Local recurrence after laparoscopic radiofrequency ablation of malignant liver tumors: Results of a contemporary series. J. Surg. Oncol. 115, 830–834 (2017).
pubmed: 28320045
doi: 10.1002/jso.24599
Saederup, N. et al. Selective chemokine receptor usage by central nervous system myeloid cells in CCR2-red fluorescent protein knock-in mice. PLoS ONE 5, e13693 (2010).
pubmed: 21060874
pmcid: 2965160
doi: 10.1371/journal.pone.0013693
Freyer, L. et al. A loss-of-function and H2B-Venus transcriptional reporter allele for Gata6 in mice. BMC Dev. Biol. 15, 38 (2015).
pubmed: 26498761
pmcid: 4619391
doi: 10.1186/s12861-015-0086-5
Gül, N. et al. Macrophages eliminate circulating tumor cells after monoclonal antibody therapy. J. Clin. Invest. 124, 812–823 (2014).
pubmed: 24430180
pmcid: 3904600
doi: 10.1172/JCI66776
Andonegui, G. et al. Endothelium-derived Toll-like receptor-4 is the key molecule in LPS-induced neutrophil sequestration into lungs. J. Clin. Invest. 111, 1011–1020 (2003).
pubmed: 12671050
pmcid: 152584
doi: 10.1172/JCI16510
Wang, J. et al. Visualizing the function and fate of neutrophils in sterile injury and repair. Science 358, 111–116 (2017).
pubmed: 28983053
doi: 10.1126/science.aam9690
Gautier, E. L., Ivanov, S., Lesnik, P. & Randolph, G. J. Local apoptosis mediates clearance of macrophages from resolving inflammation in mice. Blood 122, 2714–2722 (2013).
pubmed: 23974197
pmcid: 3795463
doi: 10.1182/blood-2013-01-478206
Kinoshita, M. et al. Characterization of two F4/80-positive Kupffer cell subsets by their function and phenotype in mice. J. Hepatol. 53, 903–910 (2010).
pubmed: 20739085
doi: 10.1016/j.jhep.2010.04.037
Crescitelli, R. et al. Distinct RNA profiles in subpopulations of extracellular vesicles: apoptotic bodies, microvesicles and exosomes. J. Extracell. Vesicles 2, https://doi.org/10.3402/jev.v2i0.20677 (2013).