Susceptibility genes of hyperuricemia and gout.

Gout Hyperuricemia Serum uric acid Single nucleotide polymorphism Susceptibility gene

Journal

Hereditas
ISSN: 1601-5223
Titre abrégé: Hereditas
Pays: England
ID NLM: 0374654

Informations de publication

Date de publication:
04 Aug 2022
Historique:
received: 10 04 2022
accepted: 03 07 2022
entrez: 3 8 2022
pubmed: 4 8 2022
medline: 6 8 2022
Statut: epublish

Résumé

Gout is a chronic metabolic disease that seriously affects human health. It is also a major challenge facing the world, which has brought a heavy burden to patients and society. Hyperuricemia (HUA) is the most important risk factor for gout. In recent years, with the improvement of living standards and the change of dietary habits, the incidence of gout in the world has increased dramatically, and gradually tends to be younger. An increasing number of studies have shown that gene mutations may play an important role in the development of HUA and gout. Therefore, we reviewed the existing literature and summarized the susceptibility genes and research status of HUA and gout, in order to provide reference for the early diagnosis, individualized treatment and the development of new targeted drugs of HUA and gout.

Identifiants

pubmed: 35922835
doi: 10.1186/s41065-022-00243-y
pii: 10.1186/s41065-022-00243-y
pmc: PMC9351246
doi:

Substances chimiques

Uric Acid 268B43MJ25

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

30

Informations de copyright

© 2022. The Author(s).

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Auteurs

Yue-Li Nian (YL)

Laboratory Medicine Center, Lanzhou University Second Hospital, Lanzhou, 730030, China.

Chong-Ge You (CG)

Laboratory Medicine Center, Lanzhou University Second Hospital, Lanzhou, 730030, China. youchg@lzu.edu.cn.

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