Ultra-High-Field 7 T Magnetic Resonance Imaging Including Dynamic and Static Contrast-Enhanced T1-Weighted Imaging Improves Detection of Secreting Pituitary Microadenomas.
Journal
Investigative radiology
ISSN: 1536-0210
Titre abrégé: Invest Radiol
Pays: United States
ID NLM: 0045377
Informations de publication
Date de publication:
01 09 2022
01 09 2022
Historique:
entrez:
4
8
2022
pubmed:
5
8
2022
medline:
9
8
2022
Statut:
ppublish
Résumé
A prospective preoperative evaluation of 7 T ultra-high-field magnetic resonance imaging (MRI) in patients with suspected pituitary microadenomas for both adenoma detection and intrasellar localization compared with 3 T MRI was carried out. Patients underwent prospective preoperative standardized 3 and 7 T MRI. A distinct qualitative (lesion detection, intrasellar lesion location) and quantitative (lesion diameters, T1/T2 signal intensity ratio of the lesion to normal pituitary gland tissue) analysis was performed, along with an evaluation of image quality (IQ) regarding overall IQ, anatomical parameters, and artifacts; the findings of the qualitative analysis were compared with intraoperative findings and endocrinological outcomes. Sixteen patients (mean age, 43 ± 16 years; 13 women) with pituitary microadenomas were included. Using 7 T MRI allowed the detection of 15 microadenomas-3 more than 3 T MRI. In addition, 7 T MRI allowed more precise lesion localization with 93.75% (15/16) agreement with intraoperative findings, compared with 75% (12/16) agreement using 3 T MRI. Lesion diameters showed no significant difference between 3 and 7 T MRI. T1 and T2 signal intensity ratio between microadenomas and normal pituitary gland tissue were higher in 7 T MRI than in 3 T MRI. The overall IQ and the IQ of each anatomical parameter of 7 T MRI were rated higher than those of 3 T MRI. No significant differences in susceptibility or head motion artifacts were observed between 3 and 7 T MRI; however, 7 T MRI was more susceptible to pulsation artifacts. Ultra-high-field MRI surpasses 3 T MRI in pituitary microadenoma detection and enables more precise delineation with higher correlation with intraoperative findings. Thus, 7 T sellar imaging is a promising option-especially in previously magnetic resonance-negative patients with endocrinologically confirmed hormone oversecretion-and helps reduce the need for invasive diagnostics.
Identifiants
pubmed: 35925660
doi: 10.1097/RLI.0000000000000872
pii: 00004424-202209000-00002
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
567-574Informations de copyright
Copyright © 2022 Wolters Kluwer Health, Inc. All rights reserved.
Déclaration de conflit d'intérêts
Conflicts of interest and sources of funding: none declared.
Références
Tabarin A, Laurent F, Catargi B, et al. Comparative evaluation of conventional and dynamic magnetic resonance imaging of the pituitary gland for the diagnosis of Cushing's disease. Clin Endocrinol (Oxf) . 1998;49:293–300.
Kucharczyk W, Bishop JE, Plewes DB, et al. Detection of pituitary microadenomas: comparison of dynamic keyhole fast spin-echo, unenhanced, and conventional contrast-enhanced MR imaging. AJR Am J Roentgenol . 1994;163:671–679.
Deutschbein T, Jaursch-Hancke C, Knappe UJ, et al. First German guideline on diagnostics and therapy of clinically non-functioning pituitary tumors. Exp Clin Endocrinol Diabetes . 2021;129:250–264.
Famini P, Maya MM, Melmed S. Pituitary magnetic resonance imaging for sellar and parasellar masses: ten-year experience in 2598 patients. J Clin Endocrinol Metab . 2011;96:1633–1641.
Lonser RR, Nieman L, Oldfield EH. Cushing's disease: pathobiology, diagnosis, and management. J Neurosurg . 2017;126:404–417.
Wagner-Bartak NA, Baiomy A, Habra MA, et al. Cushing syndrome: diagnostic workup and imaging features, with clinical and pathologic correlation. AJR Am J Roentgenol . 2017;209:19–32.
Barrou Z, Abecassis JP, Guilhaume B, et al. Magnetic resonance imaging in Cushing disease. Prediction of surgical results. Presse Med . 1997;26:7–11.
Bochicchio D, Losa M, Buchfelder M. Factors influencing the immediate and late outcome of Cushing's disease treated by transsphenoidal surgery: a retrospective study by the European Cushing's Disease Survey Group. J Clin Endocrinol Metab . 1995;80:3114–3120.
Rees DA, Hanna FW, Davies JS, et al. Long-term follow-up results of transsphenoidal surgery for Cushing's disease in a single centre using strict criteria for remission. Clin Endocrinol (Oxf) . 2002;56:541–551.
Rollin G, Ferreira NP, Czepielewski MA. Prospective evaluation of transsphenoidal pituitary surgery in 108 patients with Cushing's disease. Arq Bras Endocrinol Metabol . 2007;51:1355–1361.
Yamada S, Fukuhara N, Nishioka H, et al. Surgical management and outcomes in patients with Cushing disease with negative pituitary magnetic resonance imaging. World Neurosurg . 2012;77(3–4):525–532.
Cosottini M, Roccatagliata L. Neuroimaging at 7 T: are we ready for clinical transition? Eur Radiol Exp . 2021;5:37.
Platt T, Ladd ME, Paech D. 7 tesla and beyond: advanced methods and clinical applications in magnetic resonance imaging. Invest Radiol . 2021;56:705–725.
Barisano G, Sepehrband F, Ma S, et al. Clinical 7 T MRI: are we there yet? A review about magnetic resonance imaging at ultra-high field. Br J Radiol . 2019;92:20180492.
Varrassi M, Cobianchi Bellisari F, Bruno F, et al. High-resolution magnetic resonance imaging at 3T of pituitary gland: advantages and pitfalls. Gland Surg . 2019;8(suppl 3):S208–S215.
Kim LJ, Lekovic GP, White WL, et al. Preliminary experience with 3-tesla MRI and Cushing’s disease. Skull Base . 2007;17:273–277.
Wolfsberger S, Ba-Ssalamah A, Pinker K, et al. Application of three-tesla magnetic resonance imaging for diagnosis and surgery of sellar lesions. J Neurosurg . 2004;100:278–286.
Patel V, Liu CJ, Shiroishi MS, et al. Ultra-high field magnetic resonance imaging for localization of corticotropin-secreting pituitary adenomas. Neuroradiology . 2020;62:1051–1054.
Rutland JW, Pawha P, Belani P, et al. Tumor T2 signal intensity and stalk angulation correlates with endocrine status in pituitary adenoma patients: a quantitative 7 tesla MRI study. Neuroradiology . 2020;62:473–482.
Yao A, Rutland JW, Verma G, et al. Pituitary adenoma consistency: direct correlation of ultrahigh field 7T MRI with histopathological analysis. Eur J Radiol . 2020;126:108931.
Rutland JW, Loewenstern J, Ranti D, et al. Analysis of 7-tesla diffusion-weighted imaging in the prediction of pituitary macroadenoma consistency. J Neurosurg . 2020;134:771–779.
Nakazawa H, Shibamoto Y, Tsugawa T, et al. Efficacy of magnetic resonance imaging at 3 T compared with 1.5 T in small pituitary tumors for stereotactic radiosurgery planning. Jpn J Radiol . 2014;32:22–29.
de Rotte AA, van der Kolk AG, Rutgers D, et al. Feasibility of high-resolution pituitary MRI at 7.0 tesla. Eur Radiol . 2014;24:2005–2011.
de Rotte AA, Groenewegen A, Rutgers DR, et al. High resolution pituitary gland MRI at 7.0 tesla: a clinical evaluation in Cushing's disease. Eur Radiol . 2016;26:271–277.
Pinker K, Ba-Ssalamah A, Wolfsberger S, et al. The value of high-field MRI (3T) in the assessment of sellar lesions. Eur J Radiol . 2005;54:327–334.
Jörg Bojunga MB, Deutschbein T, Ditzen B, et al. S2k-Leitlinie “Diagnostik und Therapie klinisch hormoninaktiver Hypophysentumoren.” AWMF online. 2020.
Law M, Wang R, Liu CJ, et al. Value of pituitary gland MRI at 7 T in Cushing’s disease and relationship to inferior petrosal sinus sampling: case report. J Neurosurg . 2018;1–5.
Friedman TC, Zuckerbraun E, Lee ML, et al. Dynamic pituitary MRI has high sensitivity and specificity for the diagnosis of mild Cushing's syndrome and should be part of the initial workup. Horm Metab Res . 2007;39:451–456.
Karimian-Jazi K. Pituitary gland tumors. Radiologe . 2019;59:982–991.
Tomczak R, Merkle E, Fiala S, et al. Value of dynamic MRI in the diagnosis of hypophyseal microadenomas. Rofo . 1998;168:488–492.
Burkett BJ, Fagan AJ, Felmlee JP, et al. Clinical 7-T MRI for neuroradiology: strengths, weaknesses, and ongoing challenges. Neuroradiology . 2021;63:167–177.
Rutland JW, Delman BN, Feldman RE, et al. Utility of 7 tesla MRI for preoperative planning of endoscopic endonasal surgery for pituitary adenomas. J Neurol Surg B Skull Base . 2021;82:303–312.