Antibiotic resistance genes in the gut microbiota of mothers and linked neonates with or without sepsis from low- and middle-income countries.


Journal

Nature microbiology
ISSN: 2058-5276
Titre abrégé: Nat Microbiol
Pays: England
ID NLM: 101674869

Informations de publication

Date de publication:
09 2022
Historique:
received: 04 05 2021
accepted: 23 06 2022
pubmed: 5 8 2022
medline: 31 8 2022
entrez: 4 8 2022
Statut: ppublish

Résumé

Early development of the microbiome has been shown to affect general health and physical development of the infant and, although some studies have been undertaken in high-income countries, there are few studies from low- and middle-income countries. As part of the BARNARDS study, we examined the rectal microbiota of 2,931 neonates (term used up to 60 d) with clinical signs of sepsis and of 15,217 mothers screening for bla

Identifiants

pubmed: 35927336
doi: 10.1038/s41564-022-01184-y
pii: 10.1038/s41564-022-01184-y
pmc: PMC9417982
doi:

Substances chimiques

Anti-Bacterial Agents 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1337-1347

Informations de copyright

© 2022. The Author(s).

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Auteurs

M J Carvalho (MJ)

Institute of Infection and Immunity, Cardiff University, Cardiff, UK. mjcarvalho@ua.pt.
Institute of Biomedicine, Department of Medical Sciences, University of Aveiro, Aveiro, Portugal. mjcarvalho@ua.pt.

K Sands (K)

Institute of Infection and Immunity, Cardiff University, Cardiff, UK.
Ineos Oxford Institute of Antimicrobial Research, Department of Zoology, University of Oxford, Oxford, UK.

K Thomson (K)

Institute of Infection and Immunity, Cardiff University, Cardiff, UK.
Ineos Oxford Institute of Antimicrobial Research, Department of Zoology, University of Oxford, Oxford, UK.

E Portal (E)

Institute of Infection and Immunity, Cardiff University, Cardiff, UK.

J Mathias (J)

Institute of Infection and Immunity, Cardiff University, Cardiff, UK.

R Milton (R)

Institute of Infection and Immunity, Cardiff University, Cardiff, UK.
Centre for Trials Research, Cardiff University, Cardiff, UK.

D Gillespie (D)

Centre for Trials Research, Cardiff University, Cardiff, UK.

C Dyer (C)

Institute of Infection and Immunity, Cardiff University, Cardiff, UK.
Centre for Trials Research, Cardiff University, Cardiff, UK.

C Akpulu (C)

Institute of Infection and Immunity, Cardiff University, Cardiff, UK.
Ineos Oxford Institute of Antimicrobial Research, Department of Zoology, University of Oxford, Oxford, UK.

I Boostrom (I)

Institute of Infection and Immunity, Cardiff University, Cardiff, UK.

P Hogan (P)

Institute of Infection and Immunity, Cardiff University, Cardiff, UK.

H Saif (H)

Institute of Infection and Immunity, Cardiff University, Cardiff, UK.

A Ferreira (A)

Institute of Infection and Immunity, Cardiff University, Cardiff, UK.
Parasites and Microbes Programme, Wellcome Sanger Institute Hinxton, Hinxton, UK.

M Nieto (M)

Institute of Infection and Immunity, Cardiff University, Cardiff, UK.
Ineos Oxford Institute of Antimicrobial Research, Department of Zoology, University of Oxford, Oxford, UK.

T Hender (T)

Institute of Infection and Immunity, Cardiff University, Cardiff, UK.

K Hood (K)

Centre for Trials Research, Cardiff University, Cardiff, UK.

R Andrews (R)

Institute of Infection and Immunity, Cardiff University, Cardiff, UK.

W J Watkins (WJ)

Institute of Infection and Immunity, Cardiff University, Cardiff, UK.

B Hassan (B)

Institute of Infection and Immunity, Cardiff University, Cardiff, UK.

G Chan (G)

Division of Medical Care, Boston Children's Hospital, Boston, MA, USA.
Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Department of Pediatrics, St Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.

D Bekele (D)

Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Department of Obstetrics and Gynecology, St Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.

S Solomon (S)

Department of Microbiology, Immunology and Parasitology, St Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.

G Metaferia (G)

Department of Microbiology, Immunology and Parasitology, St Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.

S Basu (S)

Division of Bacteriology, ICMR-National Institute of Cholera and Enteric Diseases, Kolkata, India.

S Naha (S)

Division of Bacteriology, ICMR-National Institute of Cholera and Enteric Diseases, Kolkata, India.

A Sinha (A)

Division of Bacteriology, ICMR-National Institute of Cholera and Enteric Diseases, Kolkata, India.

P Chakravorty (P)

Department of Obstetrics & Gynecology, IPGMER & SSKM Hospital, Kolkata, India.

S Mukherjee (S)

Department of Neonatology, IPGMER & SSKM, Kolkata, India.

K Iregbu (K)

National Hospital, Abuja, Nigeria.

F Modibbo (F)

Murtala Muhammad Specialist Hospital, Kano City, Nigeria.

S Uwaezuoke (S)

Federal Medical Centre Jabi, Abuja, Nigeria.

L Audu (L)

National Hospital, Abuja, Nigeria.

C P Edwin (CP)

Department of Microbiology, Medway Maritime Hospital NHS Foundation Trust, Gillingham, UK.

A H Yusuf (AH)

Aminu Kano Teaching Hospital, Kano, Nigeria.

A Adeleye (A)

54gene, Lagos, Nigeria.
Bayero University, Kano, Nigeria.

A S Mukkadas (AS)

Murtala Muhammad Specialist Hospital, Kano City, Nigeria.

R Zahra (R)

Department of Microbiology, Quaid-i-Azam University, Islamabad, Pakistan.

H Shirazi (H)

Pakistan Institute of Medical Sciences, Islamabad, Pakistan.

A Muhammad (A)

Department of Microbiology, Quaid-i-Azam University, Islamabad, Pakistan.

S N Ullah (SN)

Department of Microbiology, Quaid-i-Azam University, Islamabad, Pakistan.

M H Jan (MH)

Department of Microbiology, Quaid-i-Azam University, Islamabad, Pakistan.

S Akif (S)

Department of Microbiology, Quaid-i-Azam University, Islamabad, Pakistan.

J B Mazarati (JB)

The National Reference Laboratory, Rwanda Biomedical Centre, Kigali, Rwanda.

A Rucogoza (A)

The National Reference Laboratory, Rwanda Biomedical Centre, Kigali, Rwanda.

L Gaju (L)

The National Reference Laboratory, Rwanda Biomedical Centre, Kigali, Rwanda.

S Mehtar (S)

Unit of IPC, Stellenbosch University, Cape Town, South Africa.
Infection Control Africa Network, Cape Town, South Africa.

A N H Bulabula (ANH)

Infection Control Africa Network, Cape Town, South Africa.
Department of Global Health, Stellenbosch University, Cape Town, South Africa.

A Whitelaw (A)

Division of Medical Microbiology, Stellenbosch University, Cape Town, South Africa.
National Health Laboratory Service, Tygerberg Hospital, Cape Town, South Africa.

L Roberts (L)

Division of Medical Microbiology, Stellenbosch University, Cape Town, South Africa.

T R Walsh (TR)

Institute of Infection and Immunity, Cardiff University, Cardiff, UK.
Ineos Oxford Institute of Antimicrobial Research, Department of Zoology, University of Oxford, Oxford, UK.

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