A novel QA phantom based on scintillating fiber ribbons with implementation of 2D dose tomography for small-field radiotherapy.
2D dose tomography
small-field dosimetry
water-equivalent scintillating detectors
Journal
Medical physics
ISSN: 2473-4209
Titre abrégé: Med Phys
Pays: United States
ID NLM: 0425746
Informations de publication
Date de publication:
Jan 2023
Jan 2023
Historique:
revised:
10
07
2022
received:
08
03
2022
accepted:
20
07
2022
pubmed:
8
8
2022
medline:
25
1
2023
entrez:
7
8
2022
Statut:
ppublish
Résumé
To develop a novel instrument for real-time quality assurance (QA) procedures in radiotherapy. The system implements a scintillation-based phantom and associated signal acquisition and processing modules and aims to monitor two-dimensional (2D) dose distributions of small fields. For the proposed phantom, we have designed and realized a prototype implementing six high-resolution tissue-equivalent scintillating fiber ribbons stacked with in-plane 30° rotated orientations from each other. Each ribbon output is coupled to a silicon photodiode linear array (with an element pitch of 400 μm) to detect scintillating signal, which represents the projected irradiation profile perpendicular to the ribbon's orientation. For the system providing six acquired projected dose profiles at different orientations, we have developed a two-step signal processing method to perform 2D dose reconstruction. The first step is to determine irradiation field geometry parameters using a tomographic geometry approach, and the second one is to perform specific penumbra estimation. The QA system prototype has been tested on a Novalis TrueBeam STX with a 6-MV photon beam for small elliptic fields defined by 5- and 10-mm cone collimators and for 10 × 10- and 20 × 10-mm The reconstructed 2D dose distributions have gamma index pass rates higher than 95% for all the tested configurations as compared with EBT3 film measurements with both 2%-DD/700-μm-DTA and 1%-DD/1-mm criteria. 2D global gamma analysis shows that the two-step and FBP radiation field reconstruction methods systematically outperform the SIRT approach. Moreover, higher gamma index success rates are obtained with the two-step method than with FBP in the case of the fields defined with the stereotactic cones. The proposed small-field QA system makes a use of six water-equivalent scintillating detectors (fiber ribbons) to acquire dose distribution. The developed two-step signal processing method performs tomographic 2D dose reconstruction. A system prototype has been built and tested using hospital facilities with small rectangular and elliptic fields. Testing results show 2D reconstructed dose distributions with high accuracy and resolution. Such a system could potentially be an alternative approach to film dosimetry for small-field QA, which is still widely used as reference in clinical practice.
Identifiants
pubmed: 35933612
doi: 10.1002/mp.15902
pmc: PMC10087208
doi:
Substances chimiques
Water
059QF0KO0R
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
619-632Subventions
Organisme : ITMO Cancer AVIESAN
ID : 18CP125-00
Organisme : LABEX PRIMES
ID : ANR-11-LABX-0063
Organisme : Investissements d'Avenir
ID : ANR-11-IDEX-0007
Organisme : Swiss National Science Foundation
ID : 166208
Pays : Switzerland
Informations de copyright
© 2022 The Authors. Medical Physics published by Wiley Periodicals LLC on behalf of American Association of Physicists in Medicine.
Références
J Appl Clin Med Phys. 2021 Feb;22(2):185-193
pubmed: 33440049
Phys Med. 2019 Dec;68:124-131
pubmed: 31785501
Phys Med Biol. 2016 Oct 03;61(20):R305-R343
pubmed: 27694714
Phys Imaging Radiat Oncol. 2020 Aug 29;15:108-116
pubmed: 33458335
Phys Med Biol. 2011 Sep 21;56(18):5805-21
pubmed: 21846934
Opt Express. 2016 Oct 31;24(22):25129-25147
pubmed: 27828452
J Appl Clin Med Phys. 2018 Nov;19(6):88-98
pubmed: 30216702
Med Phys. 2012 Aug;39(8):4850-7
pubmed: 22894411
Med Phys. 2018 Nov;45(11):e1123-e1145
pubmed: 30247757
Med Phys. 2023 Jan;50(1):619-632
pubmed: 35933612
J Med Phys. 2015 Apr-Jun;40(2):61-7
pubmed: 26170551
Med Phys. 2019 Feb;46(2):944-963
pubmed: 30521073
Med Phys. 2020 Jul;47(7):3153-3164
pubmed: 32215929
Med Phys. 2014 Apr;41(4):041711
pubmed: 24694131
Med Phys. 2020 Mar;47(3):1364-1371
pubmed: 31883388
Med Phys. 2012 Aug;39(8):4840-9
pubmed: 22894410
Med Phys. 2020 Aug;47(8):3636-3646
pubmed: 32445200
Med Phys. 2019 May;46(5):2468-2476
pubmed: 30897221
Radiother Oncol. 2018 Feb;126(2):205-213
pubmed: 29191457
Phys Med Biol. 2013 Apr 21;58(8):2431-44
pubmed: 23514734
Med Phys. 2020 Apr;47(4):1930-1939
pubmed: 31943221