Environmental Triggering of Type 1 Diabetes Autoimmunity.
adaptive immunity
beta cells
environmental factors
genetics
innate immunity
pathogenesis
type 1 diabetes
Journal
Frontiers in endocrinology
ISSN: 1664-2392
Titre abrégé: Front Endocrinol (Lausanne)
Pays: Switzerland
ID NLM: 101555782
Informations de publication
Date de publication:
2022
2022
Historique:
received:
01
05
2022
accepted:
20
06
2022
entrez:
8
8
2022
pubmed:
9
8
2022
medline:
10
8
2022
Statut:
epublish
Résumé
Type 1 diabetes (T1D) is a chronic autoimmune disease in which pancreatic islet β cells are destroyed by immune cells, ultimately leading to overt diabetes. The progressive increase in T1D incidence over the years points to the role of environmental factors in triggering or accelerating the disease process which develops on a highly multigenic susceptibility background. Evidence that environmental factors induce T1D has mostly been obtained in animal models. In the human, associations between viruses, dietary habits or changes in the microbiota and the development of islet cell autoantibodies or overt diabetes have been reported. So far, prediction of T1D development is mostly based on autoantibody detection. Future work should focus on identifying a causality between the different environmental risk factors and T1D development to improve prediction scores. This should allow developing preventive strategies to limit the T1D burden in the future.
Identifiants
pubmed: 35937815
doi: 10.3389/fendo.2022.933965
pmc: PMC9353023
doi:
Substances chimiques
Autoantibodies
0
Types de publication
Journal Article
Review
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
933965Informations de copyright
Copyright © 2022 Houeiss, Luce and Boitard.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Références
Diabetologia. 2014 Oct;57(10):2193-200
pubmed: 25047648
Diabetes. 2015 Jan;64(1):172-82
pubmed: 25157096
Front Endocrinol (Lausanne). 2020 Sep 15;11:568446
pubmed: 33042023
Diabetes. 2016 Jul;65(7):2094-2099
pubmed: 27207547
Front Endocrinol (Lausanne). 2017 Sep 29;8:262
pubmed: 29033899
Diabetes. 2002 Jan;51(1):73-8
pubmed: 11756325
Clin Chem. 2011 Feb;57(2):176-85
pubmed: 21205883
Discov Med. 2018 Sep;26(142):79-83
pubmed: 30399325
J Immunol. 2009 Mar 15;182(6):3696-705
pubmed: 19265148
Diabetologia. 2015 Jul;58(7):1386-93
pubmed: 25957231
Antioxid Redox Signal. 2018 Nov 10;29(14):1373-1398
pubmed: 29037052
Pediatr Diabetes. 2017 May;18(3):167-177
pubmed: 28401680
Front Endocrinol (Lausanne). 2020 Aug 19;11:569
pubmed: 32973682
Pediatr Diabetes. 2011 Dec;12(8):733-43
pubmed: 21564455
Diabetologia. 2005 Aug;48(8):1576-84
pubmed: 16003532
Nat Genet. 2015 Aug;47(8):898-905
pubmed: 26168013
Diabetologia. 2006 Sep;49(9):2105-8
pubmed: 16816951
Cell Host Microbe. 2008 Oct 16;4(4):337-49
pubmed: 18854238
J Immunol. 2013 Jun 15;190(12):6368-77
pubmed: 23670194
Nat Microbiol. 2016 Aug 22;1(11):16140
pubmed: 27782139
Lancet Diabetes Endocrinol. 2018 Feb;6(2):122-129
pubmed: 29199115
Curr Probl Pediatr Adolesc Health Care. 2012 Nov-Dec;42(10):269-91
pubmed: 23046732
J Autoimmun. 2016 Aug;72:33-46
pubmed: 27173406
Diabetologia. 2012 May;55(5):1291-4
pubmed: 22270224
Nat Commun. 2019 Aug 9;10(1):3621
pubmed: 31399563
Diabetes. 2016 Mar;65(3):794-802
pubmed: 26631741
J Exp Med. 1999 Jan 18;189(2):347-58
pubmed: 9892617
Eur J Immunol. 2003 Dec;33(12):3255-64
pubmed: 14635033
Proc Natl Acad Sci U S A. 2017 Nov 28;114(48):E10418-E10427
pubmed: 29133420
PLoS One. 2022 Jan 21;17(1):e0260100
pubmed: 35061693
Cold Spring Harb Perspect Med. 2012 Nov 01;2(11):
pubmed: 23125199
J Clin Invest. 2017 Aug 1;127(8):2881-2891
pubmed: 28762987
Diabetes. 2013 Apr;62(4):1238-44
pubmed: 23274889
Brain Res. 2015 Aug 18;1617:47-62
pubmed: 24732404
Diabetes. 2009 Jan;58(1):138-45
pubmed: 18835928
Diabetologia. 2016 Mar;59(3):414-25
pubmed: 26699650
APMIS Suppl. 2011 Jul;(132):1-19
pubmed: 21615797
Diabetologia. 2016 Nov;59(11):2448-2458
pubmed: 27506584
J Clin Invest. 2003 Mar;111(6):851-7
pubmed: 12639991
PLoS Med. 2020 Mar 2;17(3):e1003032
pubmed: 32119659
Diabetologia. 2004 Feb;47(2):225-39
pubmed: 14727023
Rev Diabet Stud. 2012 Winter;9(4):201-23
pubmed: 23804261
Nat Med. 2019 Dec;25(12):1816-1818
pubmed: 31792457
Clin Dev Immunol. 2011;2011:513210
pubmed: 21785617
Diabetes. 2018 Jan;67(1):146-154
pubmed: 29061729
Diabetes. 2016 Jul;65(7):1988-95
pubmed: 26993064
Diabetes. 2010 Jul;59(7):1561-71
pubmed: 20587799
Annu Rev Med. 2022 Jan 27;73:483-499
pubmed: 34794324
Nat Commun. 2022 Mar 21;13(1):1514
pubmed: 35314671
Diabetes. 2014 Jul;63(7):2402-14
pubmed: 24550192
Diabetes. 1999 Mar;48(3):460-8
pubmed: 10078544
Nat Med. 2019 Dec;25(12):1865-1872
pubmed: 31792456
Ann N Y Acad Sci. 2008 Dec;1150:1-13
pubmed: 19120261
Diabetes Care. 2020 Nov;43(11):e172-e173
pubmed: 32826282
Islets. 2021 Sep 3;13(5-6):106-114
pubmed: 34304698
PLoS Genet. 2011 Sep;7(9):e1002300
pubmed: 21980303
Diabetes Care. 2020 Nov;43(11):e170-e171
pubmed: 32816997
JAMA. 2016 May 3;315(17):1899-901
pubmed: 27139064
Diabetes Metab Res Rev. 2008 Jan-Feb;24(1):59-63
pubmed: 17607660
Arq Bras Endocrinol Metabol. 2013 Dec;57(9):667-76
pubmed: 24402011
Science. 1976 Jul 30;193(4251):415-7
pubmed: 180605
Sci Rep. 2019 Jun 13;9(1):7727
pubmed: 31197227
Diabetes Care. 2019 Feb;42(2):200-207
pubmed: 30655379
Diabetologia. 2003 Mar;46(3):420-5
pubmed: 12687342
Diabetes. 2010 Dec;59(12):3174-80
pubmed: 20858685
Pharmacol Res. 2005 Apr;51(4):375-80
pubmed: 15683752
Endocr Rev. 2011 Oct;32(5):623-69
pubmed: 21700723
Nat Genet. 2015 Apr;47(4):381-6
pubmed: 25751624
Clin Exp Immunol. 2007 Apr;148(1):1-16
pubmed: 17349009
Diabetologia. 2009 Jun;52(6):1143-51
pubmed: 19266182
Nature. 2014 Jan 23;505(7484):559-63
pubmed: 24336217
Curr Diab Rep. 2017 Aug 16;17(10):89
pubmed: 28815391
Diabetologia. 2019 Jul;62(7):1173-1184
pubmed: 31041471
Diabetes. 1998 Aug;47(8):1212-8
pubmed: 9703319
J Clin Endocrinol Metab. 2002 Oct;87(10):4572-9
pubmed: 12364437
Diabetologia. 2022 May;65(5):844-860
pubmed: 35142878
Diabetes. 2014 Feb;63(2):655-62
pubmed: 24009257
Diabetologia. 2013 Sep;56(9):2093-5
pubmed: 23793775
Am J Transl Res. 2013 May 24;5(4):379-92
pubmed: 23724162
JAMA Pediatr. 2019 Mar 1;173(3):280-282
pubmed: 30667473
Nutr Diabetes. 2017 May 15;7(5):e274
pubmed: 28504710
Clin Sci (Lond). 2014 Jan 1;126(1):1-18
pubmed: 24020444
Diabetologia. 2013 Aug;56(8):1705-1711
pubmed: 23657799
IUBMB Life. 2014 Nov;66(11):723-34
pubmed: 25504835
Diabetes. 1982 Feb;31(2):149-53
pubmed: 6759231
BMJ Open Diabetes Res Care. 2016 Nov 25;4(1):e000219
pubmed: 27933184
Immunity. 2015 Aug 18;43(2):304-17
pubmed: 26253786
Cold Spring Harb Perspect Med. 2012 Oct 01;2(10):
pubmed: 23028135
Front Endocrinol (Lausanne). 2020 Feb 26;11:78
pubmed: 32174888
Genes Immun. 2010 Apr;11(3):269-78
pubmed: 20090770
Nat Rev Endocrinol. 2016 May;12(5):263-273
pubmed: 27020257
Science. 2008 Oct 10;322(5899):271-5
pubmed: 18845758
JAMA Pediatr. 2013 Sep;167(9):808-15
pubmed: 23836309
Nature. 2018 Oct;562(7728):589-594
pubmed: 30356183
J Biol Chem. 2011 Jan 14;286(2):929-41
pubmed: 20980260
Acta Diabetol. 2014 Apr;51(2):199-204
pubmed: 23624551
J Biol Chem. 2016 May 20;291(21):11313-22
pubmed: 27048654
BMJ. 2011 Feb 03;342:d35
pubmed: 21292721
Diabetes Metab Res Rev. 2003 Jan-Feb;19(1):8-31
pubmed: 12592641
Nat Immunol. 2017 Jul;18(7):744-752
pubmed: 28553952
J Immunol. 2004 Sep 15;173(6):3589-93
pubmed: 15356101
Diabetologia. 2015 Sep;58(9):2027-34
pubmed: 26048237
Lancet Diabetes Endocrinol. 2020 Mar;8(3):226-238
pubmed: 31999944
N Engl J Med. 2002 May 30;346(22):1685-91
pubmed: 12037147
Curr Diab Rep. 2011 Dec;11(6):533-42
pubmed: 21912932
Diabetes Care. 2020 Jul;43(7):e79-e80
pubmed: 32393586
Diabetologia. 2008 Feb;51(2):216-26
pubmed: 18087688
Clin Rev Allergy Immunol. 2014 Oct;47(2):174-92
pubmed: 24752371
Diabetes. 2020 Aug;69(8):1763-1769
pubmed: 32439825
J Immunol. 2014 Aug 1;193(3):1024-34
pubmed: 24973447
Pediatr Diabetes. 2019 May;20(3):263-270
pubmed: 30628751
Clin Exp Immunol. 2010 Mar;159(3):338-43
pubmed: 20059481
Gut Microbes. 2021 Jan-Dec;13(1):1-18
pubmed: 34101547
Diabetologia. 2001 Jul;44(7):914-22
pubmed: 11508279
Ann N Y Acad Sci. 2006 Oct;1079:374-82
pubmed: 17130582
Diabetes Care. 2014 Sep;37(9):e194-5
pubmed: 25147260
J Exp Med. 2003 Jul 7;198(1):63-9
pubmed: 12847137
Diabetes Care. 2017 Jul;40(7):920-927
pubmed: 28487451
Pediatr Infect Dis J. 2019 May;38(5):539-541
pubmed: 30986791
Diabetes. 2016 Oct;65(10):3104-10
pubmed: 27422384
Nat Rev Immunol. 2013 Apr;13(4):243-56
pubmed: 23524461
Nat Rev Endocrinol. 2021 Mar;17(3):150-161
pubmed: 33293704
Lancet. 2018 Jun 16;391(10138):2449-2462
pubmed: 29916386
Diabetes. 2019 Apr;68(4):787-795
pubmed: 30626607
Nat Rev Endocrinol. 2020 Nov;16(11):611-612
pubmed: 32860020
JAMA. 2003 Oct 1;290(13):1721-8
pubmed: 14519706
Diabetologia. 2015 Jun;58(6):1188-97
pubmed: 25870022
Diabet Med. 2011 Jan;28(1):10-8
pubmed: 21166841
Diabetes Care. 2017 Sep;40(9):1194-1202
pubmed: 28646072
MMWR Morb Mortal Wkly Rep. 2022 Jan 14;71(2):59-65
pubmed: 35025851
Diabetes. 2000 Aug;49(8):1319-24
pubmed: 10923632
J Diabetes. 2019 Aug;11(8):632-644
pubmed: 30864231
Front Immunol. 2019 Mar 08;10:365
pubmed: 30906293
J Biol Chem. 1991 Feb 5;266(4):2112-4
pubmed: 1989973
Diabetes Care. 2009 Sep;32(9):1603-7
pubmed: 19487644
Nat Med. 2020 Aug;26(8):1247-1255
pubmed: 32770166
Diabetes Care. 2019 May;42(5):789-796
pubmed: 30796108
J Autoimmun. 2018 May;89:90-100
pubmed: 29310926
Diabetologia. 2002 Feb;45(2):217-23
pubmed: 11935153
Diabetes. 2014 Feb;63(2):446-55
pubmed: 23974921
Pediatr Diabetes. 2011 Dec;12(8):669-75
pubmed: 21435137
Diabetologia. 2012 Sep;55(9):2417-20
pubmed: 22699564
Presse Med. 2012 Dec;41(12 P 2):e636-50
pubmed: 23182678
Cold Spring Harb Perspect Med. 2012 Feb;2(2):a007799
pubmed: 22355800
Nutrients. 2019 Sep 11;11(9):
pubmed: 31514368
Diabetes. 2014 Feb;63(2):619-31
pubmed: 24353176
Rev Med Virol. 2018 May;28(3):e1974
pubmed: 29569297
Rev Infect Dis. 1985 Mar-Apr;7 Suppl 1:S170-6
pubmed: 3890104
J Autoimmun. 2007 Aug;29(1):44-51
pubmed: 17560077
Diabetes Care. 2011 Jun;34(6):1301-5
pubmed: 21515839
EBioMedicine. 2021 Oct;72:103633
pubmed: 34656932
J Physiol. 2003 Oct 15;552(Pt 2):335-44
pubmed: 14561818
Diabetologia. 2017 Jul;60(7):1223-1233
pubmed: 28474159
Curr Opin Genet Dev. 2018 Jun;50:7-16
pubmed: 29453110
Diabetologia. 2020 Mar;63(3):597-610
pubmed: 31915895
Diabet Med. 2004 Jun;21(6):507-14
pubmed: 15154932
Diabetologia. 2016 Feb;59(2):237-43
pubmed: 26564178
JAMA Pediatr. 2019 Oct 01;173(10):953-960
pubmed: 31403683
Cell Host Microbe. 2015 Feb 11;17(2):260-73
pubmed: 25662751
ISME J. 2011 Jan;5(1):82-91
pubmed: 20613793
J Autoimmun. 2018 Nov;94:7-15
pubmed: 30115527
Diabetes Care. 2014 Jul;37(7):2034-54
pubmed: 24935775
Curr Diab Rep. 2019 Nov 4;19(11):116
pubmed: 31686270
Front Endocrinol (Lausanne). 2021 Mar 25;12:622647
pubmed: 33841327
J Clin Endocrinol Metab. 2004 Aug;89(8):3896-902
pubmed: 15292324
Hum Immunol. 1997 Nov;58(1):21-9
pubmed: 9438206
Diabetologia. 2018 Nov;61(11):2344-2355
pubmed: 30074059
Diabetes. 2010 Jan;59(1):110-8
pubmed: 19794063
Sci Transl Med. 2013 Nov 13;5(211):211ra156
pubmed: 24225943
Diabetes. 2016 Sep;65(9):2686-99
pubmed: 27284108
Diabetes Care. 2015 Oct;38(10):1964-74
pubmed: 26404926
Science. 2009 Apr 17;324(5925):387-9
pubmed: 19264985
PLoS One. 2015 May 13;10(5):e0125448
pubmed: 25970503
Diabetologia. 2011 Mar;54(3):627-33
pubmed: 21153533
Lancet Diabetes Endocrinol. 2021 Jun;9(6):328-329
pubmed: 33838106
PLoS One. 2011;6(10):e26931
pubmed: 22046415
PLoS One. 2022 Feb 23;17(2):e0261103
pubmed: 35196314
Diabetes. 2014 Jul;63(7):2538-50
pubmed: 24561305
Pediatr Diabetes. 2019 Aug;20(5):574-583
pubmed: 31081243
Diabetes Care. 2015 Feb;38(2):257-63
pubmed: 25422170
Am J Epidemiol. 2013 Mar 1;177(5):411-9
pubmed: 23380046
Am J Clin Nutr. 2015 Aug;102(2):345-52
pubmed: 26156735
Sci Rep. 2019 Sep 3;9(1):12675
pubmed: 31481742
Diabetologia. 2017 Mar;60(3):424-431
pubmed: 28070615
World J Virol. 2021 Sep 25;10(5):275-287
pubmed: 34631477
Nature. 2018 Mar 8;555(7695):210-215
pubmed: 29489753
BMJ. 2018 Sep 19;362:k3547
pubmed: 30232082
Rev Diabet Stud. 2012 Winter;9(4):272-86
pubmed: 23804266
J Biol Chem. 2021 Jul;297(1):100827
pubmed: 34044020