Phylogenomic Diversity Elucidates Mechanistic Insights into Lyme Borreliae-Host Association.


Journal

mSystems
ISSN: 2379-5077
Titre abrégé: mSystems
Pays: United States
ID NLM: 101680636

Informations de publication

Date de publication:
30 08 2022
Historique:
pubmed: 9 8 2022
medline: 9 8 2022
entrez: 8 8 2022
Statut: ppublish

Résumé

Host association-the selective adaptation of pathogens to specific host species-evolves through constant interactions between host and pathogens, leaving a lot yet to be discovered on immunological mechanisms and genomic determinants. The causative agents of Lyme disease (LD) are spirochete bacteria composed of multiple species of the Borrelia burgdorferi

Identifiants

pubmed: 35938719
doi: 10.1128/msystems.00488-22
pmc: PMC9426539
doi:

Substances chimiques

Complement System Proteins 9007-36-7

Types de publication

Journal Article Research Support, U.S. Gov't, Non-P.H.S. Research Support, Non-U.S. Gov't

Langues

eng

Pagination

e0048822

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Auteurs

Matthew Combs (M)

Department of Ecology, Evolution, and Environmental Biology, Columbia Universitygrid.21729.3f, New York, New York, USA.
Department of Epidemiology and Biostatistics, School of Public Health, SUNY Downstate Health Sciences University, Brooklyn, New York, USA.
Institute for Genomics in Health, SUNY Downstate Health Sciences University, Brooklyn, New York, USA.

Ashley L Marcinkiewicz (AL)

Division of Infectious Diseases, Wadsworth Centergrid.465543.5, New York State Department of Health, Albany, New York, USA.

Alan P Dupuis (AP)

Division of Infectious Diseases, Wadsworth Centergrid.465543.5, New York State Department of Health, Albany, New York, USA.

April D Davis (AD)

Division of Infectious Diseases, Wadsworth Centergrid.465543.5, New York State Department of Health, Albany, New York, USA.

Patricia Lederman (P)

Division of Infectious Diseases, Wadsworth Centergrid.465543.5, New York State Department of Health, Albany, New York, USA.

Tristan A Nowak (TA)

Division of Infectious Diseases, Wadsworth Centergrid.465543.5, New York State Department of Health, Albany, New York, USA.
Department of Biomedical Sciences, SUNY Albany, Albany, New York, USA.

Jessica L Stout (JL)

Division of Infectious Diseases, Wadsworth Centergrid.465543.5, New York State Department of Health, Albany, New York, USA.

Klemen Strle (K)

Division of Infectious Diseases, Wadsworth Centergrid.465543.5, New York State Department of Health, Albany, New York, USA.
Department of Biomedical Sciences, SUNY Albany, Albany, New York, USA.

Volker Fingerle (V)

German National Reference Centre for Borrelia, Bavarian Health and Food Safety Authority, Oberschleissheim, Germany.

Gabriele Margos (G)

German National Reference Centre for Borrelia, Bavarian Health and Food Safety Authority, Oberschleissheim, Germany.

Alexander T Ciota (AT)

Division of Infectious Diseases, Wadsworth Centergrid.465543.5, New York State Department of Health, Albany, New York, USA.
Department of Biomedical Sciences, SUNY Albany, Albany, New York, USA.

Maria A Diuk-Wasser (MA)

Department of Ecology, Evolution, and Environmental Biology, Columbia Universitygrid.21729.3f, New York, New York, USA.

Sergios-Orestis Kolokotronis (SO)

Department of Epidemiology and Biostatistics, School of Public Health, SUNY Downstate Health Sciences University, Brooklyn, New York, USA.
Institute for Genomics in Health, SUNY Downstate Health Sciences University, Brooklyn, New York, USA.
Division of Infectious Diseases, Department of Medicine, College of Medicine, SUNY Downstate Health Sciences University, Brooklyn, New York, USA.
Department of Cell Biology, College of Medicine, SUNY Downstate Health Sciences University, Brooklyn, New York, USA.

Yi-Pin Lin (YP)

Division of Infectious Diseases, Wadsworth Centergrid.465543.5, New York State Department of Health, Albany, New York, USA.
Department of Biomedical Sciences, SUNY Albany, Albany, New York, USA.

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Classifications MeSH