AhrC Negatively Regulates Streptococcus mutans Arginine Biosynthesis.


Journal

Microbiology spectrum
ISSN: 2165-0497
Titre abrégé: Microbiol Spectr
Pays: United States
ID NLM: 101634614

Informations de publication

Date de publication:
31 08 2022
Historique:
pubmed: 9 8 2022
medline: 9 9 2022
entrez: 8 8 2022
Statut: ppublish

Résumé

Streptococcus mutans is a primary cariogenic pathogen in humans. Arginine metabolism is required for bacterial growth. In S. mutans, however, the involvement of transcription factors in regulating arginine metabolism is unclear. The purpose of this study was to investigate the function and mechanism of ArgR family transcription factors in S. mutans. Here, we identified an ArgR (arginine repressor) family transcription factor named AhrC, which negatively regulates arginine biosynthesis and biofilm formation in S. mutans. The

Identifiants

pubmed: 35938859
doi: 10.1128/spectrum.00721-22
pmc: PMC9430756
doi:

Substances chimiques

Bacterial Proteins 0
Transcription Factors 0
Water 059QF0KO0R
Arginine 94ZLA3W45F

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e0072122

Références

Lancet. 2007 Jan 6;369(9555):51-9
pubmed: 17208642
Appl Environ Microbiol. 2011 Nov;77(22):8025-33
pubmed: 21948849
J Dent Res. 2015 Feb;94(2):344-53
pubmed: 25477312
Mol Oral Microbiol. 2019 Oct;34(5):194-208
pubmed: 31287946
Biochem Biophys Res Commun. 2012 Mar 23;419(4):715-8
pubmed: 22386992
Microbiol Mol Biol Rev. 2007 Mar;71(1):36-47
pubmed: 17347518
Eur J Biochem. 2000 Aug;267(16):5217-26
pubmed: 10931207
mSphere. 2017 Aug 23;2(4):
pubmed: 28861520
J Bacteriol. 2006 Nov;188(21):7344-53
pubmed: 17050922
Environ Microbiol. 2015 Nov;17(11):4469-83
pubmed: 25950829
J Bacteriol. 2009 Apr;191(7):2153-62
pubmed: 19168613
Caries Res. 2019;53(5):514-526
pubmed: 30947169
Eur J Biochem. 1997 Dec 1;250(2):232-41
pubmed: 9428669
J Dent Res. 2020 Oct;99(11):1270-1278
pubmed: 32485128
Sci Rep. 2020 Aug 12;10(1):13623
pubmed: 32788689
Zhonghua Kou Qiang Yi Xue Za Zhi. 2011 Aug;46(8):478-83
pubmed: 22169745
J Dent Res. 2021 Aug;100(9):968-976
pubmed: 33749354
Can J Microbiol. 2010 Jul;56(7):539-47
pubmed: 20651853
Bioinformatics. 2011 Apr 1;27(7):1017-8
pubmed: 21330290
Int J Mol Sci. 2022 Apr 15;23(8):
pubmed: 35457206
mSystems. 2021 Aug 31;6(4):e0078821
pubmed: 34427509
Int J Oral Sci. 2012 Sep;4(3):135-40
pubmed: 22996271
Bioinformatics. 2014 Aug 1;30(15):2114-20
pubmed: 24695404
Proc Natl Acad Sci U S A. 2019 May 7;116(19):9578-9585
pubmed: 31004054
Sci Rep. 2017 Dec 7;7(1):17183
pubmed: 29215019
J Bacteriol. 2018 Aug 24;200(18):
pubmed: 29986940
Infect Immun. 2000 Feb;68(2):925-30
pubmed: 10639465
Infect Immun. 2013 May;81(5):1696-708
pubmed: 23460519
Genome Biol. 2015 Jan 13;16:1
pubmed: 25583448
BMC Microbiol. 2010 Sep 16;10:242
pubmed: 20843371
Appl Microbiol Biotechnol. 2020 Oct;104(20):8775-8787
pubmed: 32880693
Genes (Basel). 2020 Apr 15;11(4):
pubmed: 32326414
Trends Microbiol. 2018 Mar;26(3):229-242
pubmed: 29097091
J Nutr. 2007 Jun;137(6 Suppl 2):1602S-1609S
pubmed: 17513435
Microbiology (Reading). 2008 Oct;154(Pt 10):3053-3060
pubmed: 18832311
Methods Mol Biol. 2019;1978:199-217
pubmed: 31119665
Mol Oral Microbiol. 2018 Apr;33(2):143-154
pubmed: 29139600
PLoS One. 2012;7(3):e32697
pubmed: 22403700
J Oral Microbiol. 2022 Jan 07;14(1):2015166
pubmed: 35024088
Mol Microbiol. 2021 Jan;115(1):70-83
pubmed: 32881130
Mol Microbiol. 2010 Mar;75(5):1145-58
pubmed: 20487301
J Bacteriol. 2006 Jun;188(11):3748-56
pubmed: 16707667
Front Microbiol. 2019 Jan 14;9:3224
pubmed: 30692967
Int J Oral Sci. 2020 May 9;12(1):15
pubmed: 32385260
J Biol Chem. 2011 Dec 30;286(52):44594-605
pubmed: 22084243
Proc Natl Acad Sci U S A. 2020 Jun 2;117(22):12387-12393
pubmed: 32409599
Genome Res. 2004 Jun;14(6):1188-90
pubmed: 15173120
Nat Methods. 2008 Jul;5(7):621-8
pubmed: 18516045
Appl Environ Microbiol. 2019 Apr 18;85(9):
pubmed: 30824455
Curr Opin Microbiol. 2008 Apr;11(2):87-93
pubmed: 18359269
Biochem Soc Trans. 2004 Apr;32(Pt 2):310-3
pubmed: 15046597
Microbiology (Reading). 2011 Feb;157(Pt 2):572-582
pubmed: 20947575
Mol Oral Microbiol. 2018 Feb;33(1):47-58
pubmed: 28845576
Lancet. 2019 Jul 20;394(10194):249-260
pubmed: 31327369
Sci Adv. 2020 Jul 22;6(30):eaay9597
pubmed: 32832655
Appl Environ Microbiol. 2017 Jul 17;83(15):
pubmed: 28526785
Front Microbiol. 2017 Jan 31;8:145
pubmed: 28217122
Sci Rep. 2017 Aug 3;7(1):7206
pubmed: 28775282
Biochimie. 2019 Dec;167:34-41
pubmed: 31491441
Biol Chem. 2019 Oct 25;400(11):1397-1427
pubmed: 31188742
Proc Natl Acad Sci U S A. 2020 Jun 2;117(22):12375-12386
pubmed: 32424080
J Bacteriol. 2015 Aug 1;197(15):2545-57
pubmed: 26013484

Auteurs

Meiling Jing (M)

State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan Universitygrid.13291.38, Chengdu, China.
Department of Operative Dentistry and Endodontics, West China Hospital of Stomatology, Sichuan Universitygrid.13291.38, Chengdu, China.

Ting Zheng (T)

State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan Universitygrid.13291.38, Chengdu, China.

Tao Gong (T)

State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan Universitygrid.13291.38, Chengdu, China.

Jiangchuan Yan (J)

State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan Universitygrid.13291.38, Chengdu, China.

Jiamin Chen (J)

State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan Universitygrid.13291.38, Chengdu, China.
Department of Operative Dentistry and Endodontics, West China Hospital of Stomatology, Sichuan Universitygrid.13291.38, Chengdu, China.

Yongwang Lin (Y)

State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan Universitygrid.13291.38, Chengdu, China.
Department of Operative Dentistry and Endodontics, West China Hospital of Stomatology, Sichuan Universitygrid.13291.38, Chengdu, China.

Boyu Tang (B)

State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan Universitygrid.13291.38, Chengdu, China.
Department of Operative Dentistry and Endodontics, West China Hospital of Stomatology, Sichuan Universitygrid.13291.38, Chengdu, China.

Qizhao Ma (Q)

State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan Universitygrid.13291.38, Chengdu, China.
Department of Pediatric Dentistry, West China Hospital of Stomatology, Sichuan Universitygrid.13291.38, Chengdu, China.

Xuedong Zhou (X)

State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan Universitygrid.13291.38, Chengdu, China.
Department of Operative Dentistry and Endodontics, West China Hospital of Stomatology, Sichuan Universitygrid.13291.38, Chengdu, China.

Yuqing Li (Y)

State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan Universitygrid.13291.38, Chengdu, China.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH