A lightweight magnetically shielded room with active shielding.


Journal

Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288

Informations de publication

Date de publication:
09 08 2022
Historique:
received: 31 01 2022
accepted: 25 07 2022
entrez: 9 8 2022
pubmed: 10 8 2022
medline: 12 8 2022
Statut: epublish

Résumé

Magnetically shielded rooms (MSRs) use multiple layers of materials such as MuMetal to screen external magnetic fields that would otherwise interfere with high precision magnetic field measurements such as magnetoencephalography (MEG). Optically pumped magnetometers (OPMs) have enabled the development of wearable MEG systems which have the potential to provide a motion tolerant functional brain imaging system with high spatiotemporal resolution. Despite significant promise, OPMs impose stringent magnetic shielding requirements, operating around a zero magnetic field resonance within a dynamic range of ± 5 nT. MSRs developed for OPM-MEG must therefore effectively shield external sources and provide a low remnant magnetic field inside the enclosure. Existing MSRs optimised for OPM-MEG are expensive, heavy, and difficult to site. Electromagnetic coils are used to further cancel the remnant field inside the MSR enabling participant movements during OPM-MEG, but present coil systems are challenging to engineer and occupy space in the MSR limiting participant movements and negatively impacting patient experience. Here we present a lightweight MSR design (30% reduction in weight and 40-60% reduction in external dimensions compared to a standard OPM-optimised MSR) which takes significant steps towards addressing these barriers. We also designed a 'window coil' active shielding system, featuring a series of simple rectangular coils placed directly onto the walls of the MSR. By mapping the remnant magnetic field inside the MSR, and the magnetic field produced by the coils, we can identify optimal coil currents and cancel the remnant magnetic field over the central cubic metre to just |B|= 670 ± 160 pT. These advances reduce the cost, installation time and siting restrictions of MSRs which will be essential for the widespread deployment of OPM-MEG.

Identifiants

pubmed: 35945239
doi: 10.1038/s41598-022-17346-1
pii: 10.1038/s41598-022-17346-1
pmc: PMC9363499
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

13561

Subventions

Organisme : Wellcome Trust
ID : 203257/Z/16/Z
Pays : United Kingdom
Organisme : NIMH NIH HHS
ID : R44 MH110288
Pays : United States
Organisme : Wellcome Trust
ID : 203257/B/16/Z
Pays : United Kingdom

Informations de copyright

© 2022. The Author(s).

Références

Neuron. 2019 Oct 23;104(2):189-204
pubmed: 31647893
J Magn Reson. 2013 Nov;236:95-104
pubmed: 24095841
Sci Rep. 2019 Oct 2;9(1):14196
pubmed: 31578383
Neuroimage. 2020 Oct 1;219:116995
pubmed: 32480036
Rev Sci Instrum. 2014 Jul;85(7):075106
pubmed: 25085172
PLoS One. 2020 Jan 24;15(1):e0227684
pubmed: 31978102
Neuroimage. 2019 Jul 1;194:244-258
pubmed: 30885786
Neuroimage. 2021 Nov 1;241:118401
pubmed: 34273527
Phys Rev Lett. 2002 Sep 23;89(13):130801
pubmed: 12225013
Phys Rev Lett. 2019 Oct 4;123(14):143003
pubmed: 31702217
Science. 1968 Aug 23;161(3843):784-6
pubmed: 5663803
Phys Med Biol. 2013 Nov 21;58(22):8153-61
pubmed: 24200837
Sci Rep. 2021 Nov 22;11(1):22650
pubmed: 34811388
Neuroimage. 2015 Jan 15;105:462-72
pubmed: 25462795
Neuroimage. 2018 Nov 1;181:760-774
pubmed: 30031934
Neuroimage. 2019 Oct 1;199:408-417
pubmed: 31173906
IEEE Trans Biomed Eng. 2022 Feb;69(2):528-536
pubmed: 34324421
Nature. 2018 Mar 29;555(7698):657-661
pubmed: 29562238
Nat Neurosci. 2017 Feb 23;20(3):327-339
pubmed: 28230841

Auteurs

Niall Holmes (N)

Sir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, University Park, Nottingham, NG7 2RD, UK. niall.holmes@nottingham.ac.uk.

Molly Rea (M)

Sir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, University Park, Nottingham, NG7 2RD, UK.

James Chalmers (J)

Magnetic Shields Limited, Headcorn Road, Staplehurst, Tonbridge, Kent, TN12 0DS, UK.

James Leggett (J)

Sir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, University Park, Nottingham, NG7 2RD, UK.

Lucy J Edwards (LJ)

Sir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, University Park, Nottingham, NG7 2RD, UK.

Paul Nell (P)

Magnetic Shields Limited, Headcorn Road, Staplehurst, Tonbridge, Kent, TN12 0DS, UK.

Stephen Pink (S)

Magnetic Shields Limited, Headcorn Road, Staplehurst, Tonbridge, Kent, TN12 0DS, UK.

Prashant Patel (P)

Magnetic Shields Limited, Headcorn Road, Staplehurst, Tonbridge, Kent, TN12 0DS, UK.

Jack Wood (J)

Magnetic Shields Limited, Headcorn Road, Staplehurst, Tonbridge, Kent, TN12 0DS, UK.

Nick Murby (N)

Magnetic Shields Limited, Headcorn Road, Staplehurst, Tonbridge, Kent, TN12 0DS, UK.

David Woolger (D)

Magnetic Shields Limited, Headcorn Road, Staplehurst, Tonbridge, Kent, TN12 0DS, UK.

Eliot Dawson (E)

Cerca Magnetics Limited, Headcorn Road, Staplehurst, Tonbridge, Kent, TN12 0DS, UK.

Christopher Mariani (C)

Cerca Magnetics Limited, Headcorn Road, Staplehurst, Tonbridge, Kent, TN12 0DS, UK.

Tim M Tierney (TM)

Wellcome Centre for Human Neuroimaging, UCL Institute of Neurology, London, WC1N 3AR, UK.

Stephanie Mellor (S)

Wellcome Centre for Human Neuroimaging, UCL Institute of Neurology, London, WC1N 3AR, UK.

George C O'Neill (GC)

Wellcome Centre for Human Neuroimaging, UCL Institute of Neurology, London, WC1N 3AR, UK.

Elena Boto (E)

Sir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, University Park, Nottingham, NG7 2RD, UK.

Ryan M Hill (RM)

Sir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, University Park, Nottingham, NG7 2RD, UK.

Vishal Shah (V)

QuSpin Inc., 331 South 104th Street, Suite 130, Louisville, CO, 80027, USA.

James Osborne (J)

QuSpin Inc., 331 South 104th Street, Suite 130, Louisville, CO, 80027, USA.

Rosemarie Pardington (R)

Young Epilepsy, St. Piers Lane, Lingfield, Surrey, RH7 6PW, UK.

Peter Fierlinger (P)

Department of Physics, Technical University Munich, 85748, Garching, Germany.

Gareth R Barnes (GR)

Wellcome Centre for Human Neuroimaging, UCL Institute of Neurology, London, WC1N 3AR, UK.

Paul Glover (P)

Sir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, University Park, Nottingham, NG7 2RD, UK.

Matthew J Brookes (MJ)

Sir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, University Park, Nottingham, NG7 2RD, UK.

Richard Bowtell (R)

Sir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, University Park, Nottingham, NG7 2RD, UK.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH