Focal amyloid and asymmetric tau in an imaging-to-autopsy case of clinical primary progressive aphasia with Alzheimer disease neuropathology.
Alzheimer disease
Amyloid
Florbetapir
Flortaucipir
Positron emission tomography
Primary progressive aphasia
Stereology
Tau
Journal
Acta neuropathologica communications
ISSN: 2051-5960
Titre abrégé: Acta Neuropathol Commun
Pays: England
ID NLM: 101610673
Informations de publication
Date de publication:
09 08 2022
09 08 2022
Historique:
received:
24
05
2022
accepted:
17
07
2022
entrez:
9
8
2022
pubmed:
10
8
2022
medline:
12
8
2022
Statut:
epublish
Résumé
Quantification of in vivo amyloid and tau PET imaging relationships with postmortem measurements are critical for validating the sensitivity and specificity imaging biomarkers across clinical phenotypes with Alzheimer disease neuropathologic change (ADNC). This study examined the quantitative relationship between regional binding of in vivo
Identifiants
pubmed: 35945628
doi: 10.1186/s40478-022-01412-w
pii: 10.1186/s40478-022-01412-w
pmc: PMC9361632
doi:
Substances chimiques
Amyloid
0
Carbolines
0
tau Proteins
0
Types de publication
Case Reports
Journal Article
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
111Subventions
Organisme : NIA NIH HHS
ID : R01 AG056258
Pays : United States
Organisme : NIA NIH HHS
ID : R01 AG077444
Pays : United States
Organisme : NINDS NIH HHS
ID : R01 NS075075
Pays : United States
Organisme : NIDCD NIH HHS
ID : R01 DC008552
Pays : United States
Organisme : NIA NIH HHS
ID : T32 AG020506
Pays : United States
Organisme : NIA NIH HHS
ID : P30 AG072977
Pays : United States
Organisme : NIA NIH HHS
ID : P30 AG013854
Pays : United States
Organisme : NINDS NIH HHS
ID : R01 NS085770
Pays : United States
Informations de copyright
© 2022. The Author(s).
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