Mitral Valve Dysfunction in Patients With Annular Calcification: JACC Review Topic of the Week.
MAC-related mitral valve dysfunction
mitral annular calcification
mitral regurgitation
mitral stenosis
transcatheter mitral valve replacement
Journal
Journal of the American College of Cardiology
ISSN: 1558-3597
Titre abrégé: J Am Coll Cardiol
Pays: United States
ID NLM: 8301365
Informations de publication
Date de publication:
16 08 2022
16 08 2022
Historique:
received:
24
02
2022
revised:
30
05
2022
accepted:
31
05
2022
entrez:
11
8
2022
pubmed:
12
8
2022
medline:
16
8
2022
Statut:
ppublish
Résumé
Mitral annular calcification (MAC) is a common clinical finding and is associated with adverse clinical outcomes, but the clinical impact of MAC-related mitral valve (MV) dysfunction remains underappreciated. Patients with MAC frequently have stenotic, regurgitant, or mixed valvular disease, and this valvular dysfunction is increasingly recognized to be independently associated with worse prognosis. MAC-related MV dysfunction is a distinct pathophysiologic entity, and importantly much of the diagnostic and therapeutic paradigm from published rheumatic MV disease research cannot be applied in this context, leaving important gaps in our knowledge. This review summarizes the current epidemiology, pathophysiology, diagnosis, and classification of MAC-related MV dysfunction and proposes both an integrative definition and an overarching approach to this important and increasingly recognized clinical condition.
Identifiants
pubmed: 35953139
pii: S0735-1097(22)05261-5
doi: 10.1016/j.jacc.2022.05.032
pmc: PMC10290884
mid: NIHMS1907284
pii:
doi:
Types de publication
Journal Article
Review
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
739-751Subventions
Organisme : NHLBI NIH HHS
ID : K23 HL159262
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL141917
Pays : United States
Informations de copyright
Copyright © 2022 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.
Déclaration de conflit d'intérêts
Funding Support and Author Disclosures This study was supported in part by a grant from the Ellison Foundation and by National Institutes of Health grant R01 HL141917 (Drs Levine and Hung). The authors have reported that they have no relationships relevant to the contents of this paper to disclose.
Références
Circulation. 2021 Jan 12;143(2):178-196
pubmed: 33428433
Circ Cardiovasc Imaging. 2019 Feb;12(2):e008513
pubmed: 30712363
Am J Cardiol. 1985 Jan 1;55(1):133-7
pubmed: 3966372
JACC Cardiovasc Imaging. 2019 Jun;12(6):1105-1107
pubmed: 30765312
Circulation. 2016 Apr 19;133(16):1594-604
pubmed: 27142604
J Am Soc Echocardiogr. 2016 May;29(5):461-9
pubmed: 26936152
J Am Soc Echocardiogr. 2008 Sep;21(9):1006-9
pubmed: 18620839
JACC Cardiovasc Interv. 2016 Jul 11;9(13):1361-71
pubmed: 27388824
JACC Cardiovasc Imaging. 2016 Nov;9(11):1318-1337
pubmed: 27832900
J Am Coll Cardiol. 1989 Mar 1;13(3):594-9
pubmed: 2918166
JACC Cardiovasc Imaging. 2017 Dec;10(12):1411-1420
pubmed: 28330654
Int J Cardiol. 2007 Dec 15;123(1):58-62
pubmed: 17320214
JACC Cardiovasc Imaging. 2021 Jan;14(1):22-40
pubmed: 32771581
J Am Coll Cardiol. 2017 May 2;69(17):2175-2192
pubmed: 28449780
Eur Heart J. 2020 Dec 1;41(45):4321-4328
pubmed: 33221855
JACC Cardiovasc Imaging. 2021 Mar;14(3):559-570
pubmed: 33582068
Am Heart J. 2013 Nov;166(5):904-12
pubmed: 24176447
J Am Soc Echocardiogr. 2013 Oct;26(10):1135-1142
pubmed: 23876995
J Am Soc Echocardiogr. 2015 Jul;28(7):786-94
pubmed: 25835341
JACC Cardiovasc Imaging. 2021 Apr;14(4):854-866
pubmed: 33248959
Circulation. 2003 Mar 25;107(11):1492-6
pubmed: 12654605
JACC Cardiovasc Imaging. 2020 Sep;13(9):1945-1957
pubmed: 32417332
Eur Heart J Cardiovasc Imaging. 2018 Mar 1;19(3):279-284
pubmed: 28460029
Am Heart J. 2012 Aug;164(2):163-76
pubmed: 22877801
J Am Coll Cardiol. 2021 Feb 2;77(4):e25-e197
pubmed: 33342586
Ann Thorac Surg. 2016 Mar;101(3):889-95
pubmed: 26545623
Circulation. 2019 Aug 13;140(7):523-525
pubmed: 31403845
J Am Soc Echocardiogr. 2018 Apr;31(4):475-490
pubmed: 29625648
J Am Coll Cardiol. 2015 Oct 27;66(17):1934-41
pubmed: 26493666
Open Heart. 2014 Sep 15;1(1):e000136
pubmed: 25332828
J Am Coll Cardiol. 2021 Jun 22;77(24):3058-3078
pubmed: 34140110
J Am Soc Echocardiogr. 2017 Feb;30(2):101-138
pubmed: 28164802
N Engl J Med. 1992 Aug 6;327(6):374-9
pubmed: 1625711
Curr Treat Options Cardiovasc Med. 2019 Mar 30;21(4):19
pubmed: 30929092
J Thorac Cardiovasc Surg. 2019 Feb;157(2):555-566
pubmed: 30385026
J Am Soc Echocardiogr. 2021 Sep;34(9):923-931
pubmed: 33857624
J Am Coll Cardiol. 2020 Jun 23;75(24):3048-3057
pubmed: 32553258
Am Heart J. 2006 Jan;151(1):39-47
pubmed: 16368289
Eur Heart J Cardiovasc Imaging. 2022 Feb 22;23(3):e111-e122
pubmed: 34591959