Angiotensin receptor blocker use is associated with upregulation of the memory-protective angiotensin type 4 receptor (AT

Humans Aged Aged, 80 and over Angiotensin Receptor Antagonists / pharmacology Up-Regulation Angiotensin-Converting Enzyme Inhibitors Brain / metabolism Alzheimer Disease / drug therapy Amyloid beta-Peptides / metabolism Cognitive Dysfunction Angiotensins Inflammation / complications
AT4R Alzheimer’s disease Angiotensin receptor blocker Brain Inflammation Oxidative stress

Journal

GeroScience
ISSN: 2509-2723
Titre abrégé: Geroscience
Pays: Switzerland
ID NLM: 101686284

Informations de publication

Date de publication:
02 2023
Historique:
received: 21 01 2022
accepted: 04 08 2022
pubmed: 16 8 2022
medline: 2 2 2023
entrez: 15 8 2022
Statut: ppublish

Résumé

The reported primary dementia-protective benefits of angiotensin II type 1 receptor (AT

Identifiants

DOI: 10.1007/s11357-022-00639-8 PMID: 35969296 PMC: PMC9886717
pubmed: 35969296
doi: 10.1007/s11357-022-00639-8
pii: 10.1007/s11357-022-00639-8
pmc: PMC9886717
doi:

Substances chimiques

Angiotensin Receptor Antagonists 0
Angiotensin-Converting Enzyme Inhibitors 0
Amyloid beta-Peptides 0
Angiotensins 0

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, N.I.H., Intramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

371-384

Subventions

Organisme : NIA NIH HHS
ID : K23 AG062807
Pays : United States
Organisme : NIA NIH HHS
ID : P30 AG021334
Pays : United States
Organisme : NIA NIH HHS
ID : R01 AG046441
Pays : United States
Organisme : NIA NIH HHS
ID : K23 AG035005
Pays : United States

Informations de copyright

© 2022. The Author(s), under exclusive licence to American Aging Association.

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Auteurs

Caglar Cosarderelioglu (C)

Division of Geriatric Medicine and Gerontology, Johns Hopkins University School of Medicine, Baltimore, MD, 21224, USA.
Department of Internal Medicine, Division of Geriatrics, Ankara University School of Medicine, Ankara, Turkey.
Department of Medical Biology, Hacettepe University School of Medicine, Ankara, Turkey.

Lolita S Nidadavolu (LS)

Division of Geriatric Medicine and Gerontology, Johns Hopkins University School of Medicine, Baltimore, MD, 21224, USA.

Claudene J George (CJ)

Department of Medicine, Division of Geriatrics, Albert Einstein College of Medicine/Montefiore Medical Center, Bronx, NY, USA.

Ruth Marx-Rattner (R)

Division of Geriatric Medicine and Gerontology, Johns Hopkins University School of Medicine, Baltimore, MD, 21224, USA.

Laura Powell (L)

Division of Geriatric Medicine and Gerontology, Johns Hopkins University School of Medicine, Baltimore, MD, 21224, USA.

Qian-Li Xue (QL)

Division of Geriatric Medicine and Gerontology, Johns Hopkins University School of Medicine, Baltimore, MD, 21224, USA.
Johns Hopkins University Center On Aging and Health, Baltimore, MD, USA.

Jing Tian (J)

Department of Biostatistics, Bloomberg School of Public Health, Baltimore, MD, USA.

Esther S Oh (ES)

Division of Geriatric Medicine and Gerontology, Johns Hopkins University School of Medicine, Baltimore, MD, 21224, USA.

Luigi Ferrucci (L)

National Institute On Aging, National Institutes of Health, Baltimore, MD, USA.

Pervin Dincer (P)

Department of Medical Biology, Hacettepe University School of Medicine, Ankara, Turkey.

David A Bennett (DA)

Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA.

Jeremy D Walston (JD)

Division of Geriatric Medicine and Gerontology, Johns Hopkins University School of Medicine, Baltimore, MD, 21224, USA.

Peter M Abadir (PM)

Division of Geriatric Medicine and Gerontology, Johns Hopkins University School of Medicine, Baltimore, MD, 21224, USA. Pabadir1@jhu.edu.

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