Myelin Content and Gait Impairment in Older Adults with Cerebral Small Vessel Disease and Mild Cognitive Impairment.

Aged Cerebral Small Vessel Diseases / complications Cognitive Dysfunction / complications Cross-Sectional Studies Female Gait Humans Magnetic Resonance Imaging Male Myelin Sheath Water White Matter / diagnostic imaging
Mobility cerebrovascular disease functional decline white matter lesion

Journal

Neurobiology of aging
ISSN: 1558-1497
Titre abrégé: Neurobiol Aging
Pays: United States
ID NLM: 8100437

Informations de publication

Date de publication:
11 2022
Historique:
received: 18 10 2021
revised: 19 02 2022
accepted: 15 03 2022
pubmed: 17 8 2022
medline: 20 9 2022
entrez: 16 8 2022
Statut: ppublish

Résumé

We investigated whether myelin is associated with gait parameters in older adults with cerebral small vessel disease (cSVD). Cross-sectional data from sixty-four participants with cSVD and mild cognitive impairment were analyzed. Myelin was assessed via MRI multi-echo gradient and spin echo T

Identifiants

DOI: 10.1016/j.neurobiolaging.2022.03.020 PMID: 35973379
pubmed: 35973379
pii: S0197-4580(22)00159-2
doi: 10.1016/j.neurobiolaging.2022.03.020
pii:
doi:

Substances chimiques

Water 059QF0KO0R

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

56-66

Subventions

Organisme : CIHR
Pays : Canada

Informations de copyright

Copyright © 2022. Published by Elsevier Inc.

Auteurs

Nárlon C Boa Sorte Silva (NC)

Djavad Mowafaghian Centre for Brain Health, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada; Department of Physical Therapy, Faculty of Medicine, University of British Columbia; Centre for Hip Health and Mobility, Vancouver Coastal Research Institute, Vancouver, British Columbia, Canada.

Elizabeth Dao (E)

Department of Radiology, University of British Columbia; International Collaboration on Repair Discoveries, Vancouver, British Columbia.

Chun Liang Hsu (CL)

Hinda and Arthur Marcus Institute for Aging Research, Hebrew SeniorLife, Boston, Massachusetts, USA.

Roger C Tam (RC)

Djavad Mowafaghian Centre for Brain Health, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada; Department of Radiology, University of British Columbia; School of Biomedical Engineering, University of British Columbia.

Ryan Stein (R)

Djavad Mowafaghian Centre for Brain Health, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada; Department of Physical Therapy, Faculty of Medicine, University of British Columbia; Centre for Hip Health and Mobility, Vancouver Coastal Research Institute, Vancouver, British Columbia, Canada.

Walid Alkeridy (W)

Djavad Mowafaghian Centre for Brain Health, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada; Division of Neurology, University of British Columbia Hospital; Department of Medicine, King Saud University, College of Medicine, Riyadh, Saudi Arabia.

Cornelia Laule (C)

Department of Radiology, University of British Columbia; International Collaboration on Repair Discoveries, Vancouver, British Columbia; Department of Pathology and Laboratory Medicine, University of British Columbia; Department of Physics and Astronomy, University of British Columbia.

Irene M Vavasour (IM)

Department of Radiology, University of British Columbia; International Collaboration on Repair Discoveries, Vancouver, British Columbia.

Teresa Liu-Ambrose (T)

Djavad Mowafaghian Centre for Brain Health, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada; Department of Physical Therapy, Faculty of Medicine, University of British Columbia; Centre for Hip Health and Mobility, Vancouver Coastal Research Institute, Vancouver, British Columbia, Canada. Electronic address: teresa.ambrose@ubc.ca.

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Classifications MeSH

questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Sujet âgé › Myelin Content and Gait Impairment in Older...
questionsmedicales.fr › Maladies cardiovasculaires › Maladies vasculaires › Angiopathies intracrâniennes › Maladies des petits vaisseaux cérébraux › Myelin Content and Gait Impairment in Older...
questionsmedicales.fr › Troubles mentaux › Troubles neurocognitifs › Troubles de la cognition › Dysfonctionnement cognitif › Myelin Content and Gait Impairment in Older...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études épidémiologiques › Études transversales › Myelin Content and Gait Impairment in Older...
questionsmedicales.fr › Phénomènes physiologiques de l'appareil locomoteur et du système nerveux › Phénomènes physiologiques du système locomoteur › Mouvement › Locomotion › Démarche › Myelin Content and Gait Impairment in Older...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Myelin Content and Gait Impairment in Older...
questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Imagerie diagnostique › Tomographie › Imagerie par résonance magnétique › Myelin Content and Gait Impairment in Older...
questionsmedicales.fr › Cellules › Neurones › Neurofibres › Gaine de myéline › Myelin Content and Gait Impairment in Older...
questionsmedicales.fr › Produits chimiques inorganiques › Composés de l'oxygène › Oxydes › Eau › Myelin Content and Gait Impairment in Older...
questionsmedicales.fr › Système nerveux › Système nerveux central › Moelle spinale › Substance blanche › Myelin Content and Gait Impairment in Older...