Design, synthesis, acetylcholinesterase, butyrylcholinesterase, and amyloid-β aggregation inhibition studies of substituted 4,4'-diimine/4,4'-diazobiphenyl derivatives.
amyloid-β
biphenyl
cholinesterase
molecular modeling
synthesis
Journal
Archiv der Pharmazie
ISSN: 1521-4184
Titre abrégé: Arch Pharm (Weinheim)
Pays: Germany
ID NLM: 0330167
Informations de publication
Date de publication:
Dec 2022
Dec 2022
Historique:
revised:
01
07
2022
received:
25
03
2022
accepted:
23
07
2022
pubmed:
18
8
2022
medline:
3
12
2022
entrez:
17
8
2022
Statut:
ppublish
Résumé
A series of 4,4'-diimine/4,4'-diazobiphenyl derivatives were designed, synthesized, and evaluated for their ability to inhibit both the acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) enzymes, as well as Aβ
Identifiants
pubmed: 35976708
doi: 10.1002/ardp.202200152
doi:
Substances chimiques
Butyrylcholinesterase
EC 3.1.1.8
Acetylcholinesterase
EC 3.1.1.7
diphenyl
2L9GJK6MGN
Cholinesterase Inhibitors
0
Amyloid beta-Peptides
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e2200152Subventions
Organisme : The Scientific and Technological Research Council of Turkey (TÜBİTAK)
ID : 216S672
Organisme : Ege University Scientific Research Program (BAP)
ID : 14ECZ040,17-BİL-001
Informations de copyright
© 2022 Deutsche Pharmazeutische Gesellschaft.
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