Phrenic nerve stimulation for the treatment of central sleep apnea in patients with heart failure.
Central sleep apnea
Heart failure
Phrenic nerve stimulation
Journal
Sleep & breathing = Schlaf & Atmung
ISSN: 1522-1709
Titre abrégé: Sleep Breath
Pays: Germany
ID NLM: 9804161
Informations de publication
Date de publication:
06 2023
06 2023
Historique:
received:
30
05
2022
accepted:
08
08
2022
revised:
22
07
2022
medline:
31
5
2023
pubmed:
18
8
2022
entrez:
17
8
2022
Statut:
ppublish
Résumé
Central sleep apnea (CSA) is associated with increased morbidity and mortality in patients with heart failure (HF). We aimed to explore the effectiveness of phrenic nerve stimulation (PNS) on CSA in patients with HF. This was a prospective and non-randomized study. The stimulation lead was inserted into the right brachiocephalic vein and attached to a proprietary neurostimulator. Monitoring was conducted during the implantation process, and all individuals underwent two-night polysomnography. A total of nine subjects with HF and CSA were enrolled in our center. There was a significant decrease in the apnea-hypopnea index (41 ± 18 vs 29 ± 25, p = 0.02) and an increase in mean arterial oxygen saturation (SaO2) (93% ± 1% vs 95% ± 2%, p = 0.03) after PNS treatment. We did not observe any significant differences of oxygen desaturation index (ODI) and SaO2 < 90% (T90) following PNS. Unilateral phrenic nerve stimulation might also categorically improve the severity of sleep apnea. In our non-randomized study, PNS may serve as a therapeutic approach for CSA in patients with HF.
Identifiants
pubmed: 35978055
doi: 10.1007/s11325-022-02699-8
pii: 10.1007/s11325-022-02699-8
pmc: PMC10227108
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1027-1032Informations de copyright
© 2022. The Author(s).
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