The musculoskeletal manifestations of haemophilia: a review of the imaging findings.


Journal

Clinical radiology
ISSN: 1365-229X
Titre abrégé: Clin Radiol
Pays: England
ID NLM: 1306016

Informations de publication

Date de publication:
10 2022
Historique:
received: 30 12 2021
revised: 29 05 2022
accepted: 28 06 2022
pubmed: 20 8 2022
medline: 21 9 2022
entrez: 19 8 2022
Statut: ppublish

Résumé

Haemophilia is a common hereditary cause of bleeding diathesis and the musculoskeletal system is frequently affected. Repeated episodes of haemarthrosis initiate a cascade towards haemophilic arthropathy, a disabling and deforming joint disease with both degenerative and inflammatory features, which include articular cartilage loss, bone erosions, and synovitis. Haemophilic pseudotumour and intra-muscular haematoma make up the remainder of the musculoskeletal manifestations of this systemic condition. Radiological assessment is vital in the assessment and follow-up of these haemophilic complications and MRI is the reference standard. This article summarises the radiological findings relevant to the diagnosis and monitoring of this complex patient group.

Identifiants

pubmed: 35985846
pii: S0009-9260(22)00332-4
doi: 10.1016/j.crad.2022.06.022
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

730-737

Informations de copyright

Crown Copyright © 2022. Published by Elsevier Ltd. All rights reserved.

Auteurs

A Ray (A)

Department of Radiology, Leeds General Infirmary, Leeds Teaching Hospitals NHS Trust, Leeds LS1 3EX, UK. Electronic address: aaronray@nhs.net.

J G Colville (JG)

Department of Radiology, Royal Liverpool University Hospital, Liverpool University Hospitals NHS Foundation Trust, Liverpool L7 8XP, UK.

R Hartley (R)

Department of Radiology, The James Cook University Hospital, South Tees NHS Trust, Middlesbrough TS43BW, UK.

E Rowbotham (E)

Department of Radiology, Chapel Allerton Hospital, Leeds Teaching Hospitals NHS Trust, Chapel Town Road, Leeds LS7 4SA, UK.

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Classifications MeSH