Risk factors for evaluating early mortality after microvascular reconstruction of head and neck cancers.


Journal

Scandinavian journal of surgery : SJS : official organ for the Finnish Surgical Society and the Scandinavian Surgical Society
ISSN: 1799-7267
Titre abrégé: Scand J Surg
Pays: England
ID NLM: 101144297

Informations de publication

Date de publication:
Dec 2022
Historique:
pubmed: 25 8 2022
medline: 3 11 2022
entrez: 24 8 2022
Statut: ppublish

Résumé

Free tissue transfer reconstruction carries significant complication rates in surgical head and neck oncology. A registry-based approach offers a possibility to investigate the factors affecting increased morbidity and early mortality, that is, death within 6 months of treatment. A retrospective registry review was conducted on a series of 317 consecutive microvascular free tissue transfers in head and neck cancer patients performed during 2013-2017 at the Helsinki University Hospital (Helsinki, Finland). All surviving patients had a minimum follow-up of 2 years (range 24-84 months). Overall, 36 (11.4%) early deaths occurred in this series. In multivariable logistic regression analysis, patients aged 75 years and older ( Early postoperative mortality most frequently affects patients aged 75 years and above, with a high ACE-27 score, advanced tumor stage, or high thrombocyte count. Therefore, preoperative assessment and patient selection should have a crucial role in this patient population.

Sections du résumé

BACKGROUND UNASSIGNED
Free tissue transfer reconstruction carries significant complication rates in surgical head and neck oncology. A registry-based approach offers a possibility to investigate the factors affecting increased morbidity and early mortality, that is, death within 6 months of treatment.
METHODS UNASSIGNED
A retrospective registry review was conducted on a series of 317 consecutive microvascular free tissue transfers in head and neck cancer patients performed during 2013-2017 at the Helsinki University Hospital (Helsinki, Finland). All surviving patients had a minimum follow-up of 2 years (range 24-84 months).
RESULTS UNASSIGNED
Overall, 36 (11.4%) early deaths occurred in this series. In multivariable logistic regression analysis, patients aged 75 years and older (
CONCLUSIONS UNASSIGNED
Early postoperative mortality most frequently affects patients aged 75 years and above, with a high ACE-27 score, advanced tumor stage, or high thrombocyte count. Therefore, preoperative assessment and patient selection should have a crucial role in this patient population.

Identifiants

pubmed: 36000730
doi: 10.1177/14574969221117010
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

83-91

Auteurs

Teija Nieminen (T)

Division of Anaesthesiology, Department of Anaesthesiology Intensive Care and Pain Medicine, Helsinki University Hospital and University of Helsinki, Haartmaninkatu 4, P.O. Box 340, 00029 HUS Helsinki, Finland; Research Program in Systems Oncology, Faculty of Medicine,University of Helsinki, Helsinki, Finland.

Morag Tolvi (M)

Department of Otorhinolaryngology - Head and Neck Surgery, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.

Patrik Lassus (P)

Patrik Lassus Department of Plastic Surgery, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.

Tommy Wilkman (T)

Tommy Wilkman Department of Plastic Surgery, Helsinki University Hospital and University of Helsinki, Helsinki, Finland Department of Oral and Maxillofacial Surgery, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.

Lasse Lehtonen (L)

HUS Diagnostic Center, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.

Antti Mäkitie (A)

Department of Otorhinolaryngology - Head and Neck Surgery, Helsinki University Hospital and University of Helsinki, Helsinki, Finland Research Program in Systems Oncology, Faculty of Medicine, University of Helsinki, Helsinki, Finland.

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Classifications MeSH