Glutamatergic and N-Acetylaspartate Metabolites in Bipolar Disorder: A Systematic Review and Meta-Analysis of Proton Magnetic Resonance Spectroscopy Studies.

Aspartic Acid / analogs & derivatives Bipolar Disorder / diagnostic imaging Depressive Disorder, Major Glutamic Acid / metabolism Glutamine / metabolism Humans Proton Magnetic Resonance Spectroscopy / methods
N-acetylaspartate NAA bipolar depression bipolar disorder glutamate magnetic resonance spectroscopy

Journal

International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791

Informations de publication

Date de publication:
11 Aug 2022
Historique:
received: 08 07 2022
revised: 08 08 2022
accepted: 09 08 2022
entrez: 26 8 2022
pubmed: 27 8 2022
medline: 30 8 2022
Statut: epublish

Résumé

The exact neurobiological mechanisms of bipolar disorder (BD) remain unknown. However, some neurometabolites could be implicated, including Glutamate (Glu), Glutamine (Gln), Glx, and N-acetylaspartate (NAA). Proton Magnetic Resonance Spectroscopy (

Identifiants

DOI: 10.3390/ijms23168974 PMID: 36012234 PMC: PMC9409038
pubmed: 36012234
pii: ijms23168974
doi: 10.3390/ijms23168974
pmc: PMC9409038
pii:
doi:

Substances chimiques

Glutamine 0RH81L854J
Aspartic Acid 30KYC7MIAI
Glutamic Acid 3KX376GY7L
N-acetylaspartate 997-55-7

Types de publication

Journal Article Meta-Analysis Review Systematic Review

Langues

eng

Sous-ensembles de citation

IM

Références

Psychiatry Res. 2013 Sep 30;213(3):230-4
pubmed: 23810640
Prog Neuropsychopharmacol Biol Psychiatry. 2013 Mar 5;41:1-5
pubmed: 23142769
Prog Neuropsychopharmacol Biol Psychiatry. 2008 Aug 1;32(6):1501-7
pubmed: 18572296
J Affect Disord. 2019 Mar 1;246:745-753
pubmed: 30623820
Bipolar Disord. 2015 Jun;17(4):450-7
pubmed: 25495884
Neurosci Biobehav Rev. 2017 Mar;74(Pt A):1-20
pubmed: 28093238
J Psychiatr Res. 2010 Apr;44(5):278-85
pubmed: 19818454
Eur Psychiatry. 2007 Nov;22(8):505-12
pubmed: 17904824
Psychiatr Pol. 2016;50(4):839-848
pubmed: 27847932
Psychiatry Res. 2008 Feb 28;162(2):113-21
pubmed: 18164911
Neuropsychopharmacology. 2007 Dec;32(12):2490-9
pubmed: 17429412
Psychiatry Res. 2017 Nov;257:327-337
pubmed: 28800512
Prog Neuropsychopharmacol Biol Psychiatry. 2012 Apr 27;37(1):176-81
pubmed: 22306485
J Psychiatr Res. 2016 Oct;81:48-55
pubmed: 27376506
Contemp Clin Trials. 2015 Nov;45(Pt A):139-45
pubmed: 26343745
Neuroreport. 2007 Oct 8;18(15):1567-70
pubmed: 17885603
Neuropsychopharmacology. 2017 Oct;42(11):2252-2258
pubmed: 28220797
Front Neuroenergetics. 2013 Dec 26;5:11
pubmed: 24421768
Acta Psychiatr Scand Suppl. 2007;(434):57-66
pubmed: 17688464
Neurosci Lett. 2017 Jan 10;637:70-74
pubmed: 27890741
World J Biol Psychiatry. 2009;10(4):285-94
pubmed: 19921970
Schizophr Res. 2015 Sep;167(1-3):64-72
pubmed: 25728835
Eur Neuropsychopharmacol. 2019 Dec;29(2):222-234
pubmed: 30558824
J Neurochem. 1999 Feb;72(2):879-82
pubmed: 9930766
Psychiatry Res. 2013 Sep 30;213(3):235-41
pubmed: 23810639
Prog Neuropsychopharmacol Biol Psychiatry. 2021 Mar 8;105:110027
pubmed: 32791168
Cell Mol Neurobiol. 2007 May;27(3):351-8
pubmed: 17235693
Eur Arch Psychiatry Clin Neurosci. 2012 Feb;262(1):23-31
pubmed: 21509595
J Affect Disord. 2011 Aug;132(3):344-55
pubmed: 21470688
Eur Neuropsychopharmacol. 2021 Jun;47:62-73
pubmed: 33581932
Psychiatry Res. 2006 Jun 30;147(1):1-25
pubmed: 16806850
Bipolar Disord. 2000 Sep;2(3 Pt 2):207-16
pubmed: 11249799
Dis Markers. 2018 Nov 25;2018:3654894
pubmed: 30595760
Biol Psychiatry. 2003 May 15;53(10):906-13
pubmed: 12742678
Arch Gen Psychiatry. 2004 Mar;61(3):300-8
pubmed: 14993118
Biol Psychiatry. 2015 Feb 1;77(3):295-303
pubmed: 24331546
Mitochondrion. 2014 Nov;19 Pt A:39-48
pubmed: 24954615
Brain Behav. 2020 Jun;10(6):e01616
pubmed: 32385970
Transl Psychiatry. 2017 Mar 28;7(3):e1071
pubmed: 28350397
Bipolar Disord. 2012 Jun;14(4):313-25
pubmed: 22631617
Psychiatry Res. 2011 Aug 30;193(2):107-12
pubmed: 21683555
Neurosci Biobehav Rev. 2009 Mar;33(3):336-54
pubmed: 18955079
J Affect Disord. 2014;167:80-4
pubmed: 25082118
Neurology. 2008 Apr 15;70(16):1353-7
pubmed: 18413589
Front Psychiatry. 2021 Jun 07;12:660850
pubmed: 34163382
Neural Plast. 2015;2015:165180
pubmed: 26075096
J Neurosci. 2004 Jul 21;24(29):6578-89
pubmed: 15269270
Prog Neuropsychopharmacol Biol Psychiatry. 2021 Jul 13;109:110233
pubmed: 33387596
J Affect Disord. 2019 Dec 1;259:82-90
pubmed: 31442883
J Affect Disord. 2018 Dec 1;241:192-199
pubmed: 30130684
Bipolar Disord. 2009 Dec;11(8):807-14
pubmed: 19922551
Biol Psychiatry. 2004 Sep 1;56(5):340-8
pubmed: 15336516
Psychiatry Res. 2001 Feb 28;106(1):35-45
pubmed: 11231098
Neurosci Biobehav Rev. 2010 Mar;34(4):533-54
pubmed: 19896972
Med Hypotheses. 2006;67(3):506-12
pubmed: 16730130
Acta Psychiatr Scand. 2008 Apr;117(4):283-8
pubmed: 18205896
Psychiatry Res. 2015 Aug 30;233(2):88-94
pubmed: 26070970
Eur Neuropsychopharmacol. 2015 Dec;25(12):2221-9
pubmed: 26476706
Prog Neuropsychopharmacol Biol Psychiatry. 2019 Jul 13;93:250-255
pubmed: 30959086
Psychol Med. 2021 Mar 12;:1-9
pubmed: 33706825
Am J Psychiatry. 2006 Feb;163(2):217-24
pubmed: 16449474
Biol Psychiatry Cogn Neurosci Neuroimaging. 2018 Dec;3(12):985-991
pubmed: 29789269
Schizophr Res. 2010 Mar;117(1):1-12
pubmed: 20071149
BMC Med Res Methodol. 2005 Apr 20;5:13
pubmed: 15840177
J Psychiatr Res. 2013 Mar;47(3):412-7
pubmed: 23312884
J Neurochem. 1993 Nov;61(5):1957-60
pubmed: 7901339
Neuroreport. 1996 May 31;7(8):1397-400
pubmed: 8856684
Schizophr Res. 2017 Sep;187:62-66
pubmed: 27839913
Biol Psychiatry. 2007 Mar 15;61(6):806-12
pubmed: 17210135
Biol Psychiatry. 2000 Mar 15;47(6):475-81
pubmed: 10715353
Prog Neurobiol. 2007 Feb;81(2):89-131
pubmed: 17275978
Am J Geriatr Psychiatry. 2019 Aug;27(8):783-793
pubmed: 31000323
J Neural Transm (Vienna). 2008 Nov;115(11):1513-8
pubmed: 18726138
Eur Arch Psychiatry Clin Neurosci. 2018 Mar;268(2):145-156
pubmed: 28357562
Bipolar Disord. 2007 Jun;9 Suppl 1:119-27
pubmed: 17543030
Neuropsychopharmacology. 2008 Jan;33(1):110-33
pubmed: 17912251
Schizophr Res. 1992 Oct;8(1):43-9
pubmed: 1329928
Schizophr Res. 2015 Feb;161(2-3):202-9
pubmed: 25480359
Amino Acids. 2013 Sep;45(3):413-8
pubmed: 22526238
J Affect Disord. 2018 Dec 1;241:282-290
pubmed: 30142586
J Affect Disord. 2014 Oct;168:380-6
pubmed: 25106035
Transl Psychiatry. 2012 Sep 11;2:e160
pubmed: 22968227
Dev Neurobiol. 2018 Mar;78(3):221-237
pubmed: 29030922
J Neurotrauma. 2004 Sep;21(9):1154-67
pubmed: 15453986
Front Biosci (Elite Ed). 2012 Jun 01;4(7):2622-30
pubmed: 22652673
Biol Psychiatry Cogn Neurosci Neuroimaging. 2021 Jul;6(7):706-715
pubmed: 33508498
Psychiatry Res. 2004 Jul 30;131(2):95-105
pubmed: 15313516
J Clin Psychopharmacol. 2017 Feb;37(1):40-45
pubmed: 27902528
Eur Arch Psychiatry Clin Neurosci. 2021 Apr;271(3):537-547
pubmed: 31993746
Eur Arch Psychiatry Clin Neurosci. 2008 Oct;258(7):394-401
pubmed: 18437276
J Affect Disord. 2018 Aug 1;235:15-19
pubmed: 29631202
Psychol Med. 2007 Jan;37(1):121-9
pubmed: 17094813
World J Biol Psychiatry. 2009;10(4 Pt 2):524-30
pubmed: 17965994
Arch Gen Psychiatry. 2011 Mar;68(3):241-51
pubmed: 21383262
Front Psychiatry. 2020 Dec 08;11:590095
pubmed: 33363485
Am J Psychiatry. 2014 Aug;171(8):829-43
pubmed: 24626773
Int J Neuropsychopharmacol. 2014 Oct 31;18(6):
pubmed: 25522399
Psychiatry Res. 2015 Aug 30;233(2):73-80
pubmed: 26050195
Int Clin Psychopharmacol. 2003 Mar;18(2):73-9
pubmed: 12598817
Hum Psychopharmacol. 2006 Jun;21(4):215-20
pubmed: 16783812
Front Psychiatry. 2019 Mar 01;10:66
pubmed: 30881316
J Affect Disord. 2016 Dec;206:315-320
pubmed: 27662572
Biol Psychiatry. 1992 Nov 15;32(10):944-9
pubmed: 1467379
Eur Neuropsychopharmacol. 2015 Jun;25(6):836-45
pubmed: 25795519
Aust N Z J Psychiatry. 2017 Jan;51(1):65-74
pubmed: 26792829
Bipolar Disord. 2016 Nov;18(7):583-590
pubmed: 27870506
Neuroscientist. 2019 Jun;25(3):208-226
pubmed: 30014771
Psychiatry Res. 2009 Apr 30;172(1):78-81
pubmed: 19239983
J Psychiatry Neurosci. 1996 Jul;21(4):248-54
pubmed: 8754593
J Clin Psychopharmacol. 2013 Aug;33(4):528-32
pubmed: 23764689
Depress Res Treat. 2012;2012:485249
pubmed: 22500219
Neuropsychopharmacology. 2013 Feb;38(3):468-75
pubmed: 23072837
Biol Psychiatry. 2018 Mar 15;83(6):484-491
pubmed: 29031411
Biol Psychiatry. 2007 Jan 15;61(2):162-6
pubmed: 16735030
Mol Psychiatry. 2009 Jul;14(7):696-704, 647
pubmed: 18347601
Arch Gen Psychiatry. 2004 May;61(5):450-8
pubmed: 15123489
Neuroimage Clin. 2021;32:102845
pubmed: 34662778
Biol Psychiatry. 2000 Jul 1;48(1):1-8
pubmed: 10913502
J Comp Neurol. 1991 Sep 22;311(4):445-62
pubmed: 1757597
Acta Neuropsychiatr. 2006 Apr;18(2):120-6
pubmed: 26989801
Ann Gen Hosp Psychiatry. 2004 Jul 30;3(1):13
pubmed: 15283867
World J Biol Psychiatry. 2014 Feb;15(2):145-54
pubmed: 23984710
J Affect Disord. 2006 Mar;91(1):87-90
pubmed: 16469390
Eur Arch Psychiatry Clin Neurosci. 1998;248(1):53-8
pubmed: 9561353
Neural Regen Res. 2012 Dec 25;7(36):2929-36
pubmed: 25317146
Bipolar Disord. 2008 Nov;10(7):849
pubmed: 19032718
World J Biol Psychiatry. 2004 Jan;5(1):38-44
pubmed: 15048634
Biol Psychiatry. 2010 Jun 1;67(11):1097-105
pubmed: 20303066
Psychiatry Res. 1998 Dec 14;84(2-3):55-60
pubmed: 10710163
Ann Transl Med. 2020 Nov;8(21):1457
pubmed: 33313202
J Affect Disord. 2017 Jan 15;208:139-144
pubmed: 27770643
Psychol Med. 1999 May;29(3):639-44
pubmed: 10405085
Biochem J. 1979 Dec 15;184(3):539-46
pubmed: 540047
Neuropsychopharmacology. 2019 Dec;44(13):2285-2293
pubmed: 31434102
CNS Neurosci Ther. 2009 Winter;15(4):309-19
pubmed: 19889129
Transl Psychiatry. 2019 May 23;9(1):149
pubmed: 31123248
Am J Psychiatry. 2003 May;160(5):873-82
pubmed: 12727690
Bipolar Disord. 2013 Jun;15(4):434-9
pubmed: 23634979
J Psychiatry Neurosci. 2012 May;37(3):185-92
pubmed: 22353634
Int J Neuropsychopharmacol. 2016 Aug 12;19(8):
pubmed: 27207914
J Clin Psychiatry. 2020 Sep 22;81(5):
pubmed: 32965803
Brain Behav Immun. 2016 Aug;56:21-33
pubmed: 26348581
J Affect Disord. 2018 Jan 1;225:108-116
pubmed: 28818755
Psychiatry Res. 2012 Aug-Sep;203(2-3):111-25
pubmed: 22981426
Mol Psychiatry. 2019 Jul;24(7):952-964
pubmed: 30315224
Transl Psychiatry. 2017 Jul 4;7(7):e1163
pubmed: 28675386
Eur Neuropsychopharmacol. 2015 Dec;25(12):2311-7
pubmed: 26428274
Clin Neurophysiol. 2015 Jun;126(6):1178-1184
pubmed: 25454340
J Affect Disord. 2005 May;86(1):61-7
pubmed: 15820271
Eur Neuropsychopharmacol. 2021 Aug;49:93-100
pubmed: 33882433
Psychopharmacology (Berl). 2014 Jan;231(2):327-32
pubmed: 23955702
J Affect Disord. 2021 Jun 15;289:81-87
pubmed: 33951550
Psychiatry Res. 2009 Jun 30;172(3):205-9
pubmed: 19386476
Magn Reson Med. 2010 Jan;63(1):1-8
pubmed: 19918902
Prog Neuropsychopharmacol Biol Psychiatry. 2009 Apr 30;33(3):427-34
pubmed: 19171176
Hum Psychopharmacol. 2002 Oct;17(7):321-7
pubmed: 12415549
J Affect Disord. 2017 Mar 15;211:153-161
pubmed: 28126615
Eur Child Adolesc Psychiatry. 2021 Jan;30(1):55-64
pubmed: 32008167
BMJ. 2003 Sep 6;327(7414):557-60
pubmed: 12958120

Auteurs

Jonathan Chabert (J)

Service de Psychiatrie Adulte, CHU Clermont-Ferrand, CNRS, Institut Pascal, Université Clermont Auvergne, 58 Rue Montalembert, 63003 Clermont-Ferrand, France.
ORCID: 0000-0002-4997-0142

Etienne Allauze (E)

Service de Psychiatrie Adulte, CHU Clermont-Ferrand, CNRS, Institut Pascal, Université Clermont Auvergne, 58 Rue Montalembert, 63003 Clermont-Ferrand, France.

Bruno Pereira (B)

Biostatistics Unit (DRCI), CHU Clermont-Ferrand, Université Clermont Auvergne, 7 Place Henri Dunant, 63000 Clermont-Ferrand, France.
ORCID: 0000-0003-3778-7161

Carine Chassain (C)

Imaging Department, CHU Clermont-Ferrand, CNRS, Institut Pascal, Université Clermont Auvergne, Clermont Auvergne INP, 58 Rue Montalembert, 63003 Clermont-Ferrand, France.

Ingrid De Chazeron (I)

Service de Psychiatrie Adulte, CHU Clermont-Ferrand, CNRS, Institut Pascal, Université Clermont Auvergne, 58 Rue Montalembert, 63003 Clermont-Ferrand, France.

Jean-Yves Rotgé (JY)

Service de Psychiatrie Adulte, Pitié-Salpêtrière Hospital, CNRS UMR 7593, 47-83 Bd de l'Hôpital, 75651 Paris, France.

Philippe Fossati (P)

Service de Psychiatrie Adulte, Pitié-Salpêtrière Hospital, CNRS UMR 7593, 47-83 Bd de l'Hôpital, 75651 Paris, France.

Pierre-Michel Llorca (PM)

Service de Psychiatrie Adulte, CHU Clermont-Ferrand, CNRS, Institut Pascal, Université Clermont Auvergne, 58 Rue Montalembert, 63003 Clermont-Ferrand, France.
ORCID: 0000-0001-7438-8990

Ludovic Samalin (L)

Service de Psychiatrie Adulte, CHU Clermont-Ferrand, CNRS, Institut Pascal, Université Clermont Auvergne, 58 Rue Montalembert, 63003 Clermont-Ferrand, France.

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Classifications MeSH

questionsmedicales.fr › Acides aminés, peptides et protéines › Acides aminés › Acides aminés excitateurs › Acide aspartique › Glutamatergic and N-Acetylaspartate...
questionsmedicales.fr › Troubles mentaux › Troubles de l'humeur › Troubles bipolaires et apparentés › Trouble bipolaire › Glutamatergic and N-Acetylaspartate...
questionsmedicales.fr › Troubles mentaux › Troubles de l'humeur › Trouble dépressif › Trouble dépressif majeur › Glutamatergic and N-Acetylaspartate...
questionsmedicales.fr › Acides aminés, peptides et protéines › Acides aminés › Acides aminés excitateurs › Acide glutamique › Glutamatergic and N-Acetylaspartate...
questionsmedicales.fr › Acides aminés, peptides et protéines › Acides aminés › Acides aminés neutres › Glutamine › Glutamatergic and N-Acetylaspartate...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Glutamatergic and N-Acetylaspartate...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Analyse spectrale › Spectroscopie par résonance magnétique › Spectroscopie par résonance magnétique du proton › Glutamatergic and N-Acetylaspartate...