Association between Maternal Characteristics and Immune Factors TGF-β1, TGF-β2, and IgA in Colostrum: An Exploratory Study in Japan.
IgA
TGF-β1
TGF-β2
colostrum
immune factors
maternal characteristics
mode of delivery
parity
Journal
Nutrients
ISSN: 2072-6643
Titre abrégé: Nutrients
Pays: Switzerland
ID NLM: 101521595
Informations de publication
Date de publication:
09 Aug 2022
09 Aug 2022
Historique:
received:
29
06
2022
revised:
05
08
2022
accepted:
05
08
2022
entrez:
26
8
2022
pubmed:
27
8
2022
medline:
30
8
2022
Statut:
epublish
Résumé
Colostrum is the first food for newborns and it contains various crucial immune factors. The concentrations of immune factors in breast milk may change depending on maternal characteristics such as body mass index, collection day, and age at first pregnancy. In this exploratory study, we investigated the association between TGF-β1, TGF-β2, and IgA in colostrum and rarely studied factors that affect breast milk components, including the use of labor-inducing medication, colostrum secretion, sex of newborns, breast or nipple problems, and nipple care. Breast milk samples were collected from 42 mothers and analyzed for TGF-β1, TGF-β2, and IgA. The results suggest that parity and mode of delivery may be correlated with the concentrations of immune factors in colostrum. However, we found no association between the immune factors in colostrum and the use of labor-inducing medications, colostrum secretion, sex of newborns, breast or nipple problems, and nipple care. These findings have some implications for further analysis of the effects of immune factors in breast milk on the prognosis of allergies in children.
Identifiants
pubmed: 36014760
pii: nu14163255
doi: 10.3390/nu14163255
pmc: PMC9416399
pii:
doi:
Substances chimiques
Immunoglobulin A
0
Immunologic Factors
0
Transforming Growth Factor beta1
0
Transforming Growth Factor beta2
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
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