Aortic root translocation and en bloc rotation of the outflow tracts surgery for complex forms of transposition of the great arteries and double outlet right ventricle: A multicenter study.


Journal

The Journal of thoracic and cardiovascular surgery
ISSN: 1097-685X
Titre abrégé: J Thorac Cardiovasc Surg
Pays: United States
ID NLM: 0376343

Informations de publication

Date de publication:
11 2022
Historique:
received: 25 02 2022
revised: 27 04 2022
accepted: 08 05 2022
pubmed: 27 8 2022
medline: 19 10 2022
entrez: 26 8 2022
Statut: ppublish

Résumé

There are several choices for the correction of complex transposition of the great arteries and double outlet right ventricle not amenable to the Rastelli-type surgery, but outcome data are limited to small series. This study aims to report results after the aortic root translocation and en bloc rotation of the outflow tract procedures. This is a retrospective, multicentric, observational study. Clinical, anatomy, procedural, and detailed follow-up data (median, 4.43 years) were collected. A total of 70 patients (62.9% male; median age, 1 year; range 4 days to 12.4 years) were included: n = 43 in the aortic root translocation group and n = 27 in the en bloc rotation group. Those in the aortic root translocation group were older (P = .01) and more likely to have had previous procedures (P < .0001), but cardiac anatomy was similar in both groups. Aortic root translocation and en bloc rotation early mortality (30 days) was similar (4.7% vs 3.7%, P = .8). Late survival and freedom from any cardiac reintervention were 92.7% and 16.9% at 15 years overall, respectively. Freedom from right ventricular outflow tract/conduit reintervention was better in the en bloc rotation group than in the aortic root translocation group (100% vs 24.5%, P = .0003), but more patients in the en bloc rotation group had moderate (or worse) aortic valve regurgitation during follow-up (16% vs 2.6%, P = .07). Both aortic root translocation and en bloc rotation are valuable surgical options for the treatment of complex transposition of the great arteries and double outlet right ventricle. In the en bloc rotation group, there was better freedom from right ventricular outflow tract reinterventions, but a higher probability of aortic valve regurgitation. Identifying the main driving forces for these observed differences requires further study of these procedures.

Identifiants

pubmed: 36028361
pii: S0022-5223(22)00799-1
doi: 10.1016/j.jtcvs.2022.05.047
pii:
doi:

Types de publication

Journal Article Multicenter Study Observational Study Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1249-1260

Commentaires et corrections

Type : CommentIn

Informations de copyright

Copyright © 2022 The Authors. Published by Elsevier Inc. All rights reserved.

Auteurs

Serban Stoica (S)

University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, United Kingdom. Electronic address: Serban.Stoica@uhbw.nhs.uk.

Michaela Kreuzer (M)

Children's Heart Center at Kepler Universitätsklinikum, Linz, Austria; Johannes Kepler University, Medical Faculty, Linz, Austria.

Dan-Mihai Dorobantu (DM)

University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, United Kingdom; Children's Health and Exercise Research Centre, University of Exeter, Exeter, United Kingdom; School of Population Health Sciences, University of Bristol, Bristol, United Kingdom.

Martin Kostolny (M)

Great Ormond Street Hospital for Children, London, United Kingdom.

Matej Nosal (M)

National Institute of Cardio-Vascular Diseases, Childrens Heart Center, Bratislava, Slovakia.

Amir-Reza Hosseinpour (AR)

Virgen del Rocio Children's Hospital, University Hospitals of Seville, Seville, Spain.

Fernando Laviana Martinez (FL)

Great Ormond Street Hospital for Children, London, United Kingdom; Virgen del Rocio Children's Hospital, University Hospitals of Seville, Seville, Spain.

Tommaso Generali (T)

Freeman Hospital, Newcastle-upon-Tyne, United Kingdom.

Asif Hasan (A)

Freeman Hospital, Newcastle-upon-Tyne, United Kingdom.

Rudolf Mair (R)

Children's Heart Center at Kepler Universitätsklinikum, Linz, Austria; Johannes Kepler University, Medical Faculty, Linz, Austria.

Mark Hazekamp (M)

Leiden University Medical Center, Leiden, the Netherlands.

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