Molecular and Kinetic Characterization of MOX-9, a Plasmid-Mediated Enzyme Representative of a Novel Sublineage of MOX-Type Class C β-Lactamases.

Bacterial Proteins / genetics Cephalosporins Clavulanic Acid Kinetics Plasmids / genetics Sulbactam Tazobactam beta-Lactamases / chemistry
MOX enzyme kineticss β-lactamases

Journal

Antimicrobial agents and chemotherapy
ISSN: 1098-6596
Titre abrégé: Antimicrob Agents Chemother
Pays: United States
ID NLM: 0315061

Informations de publication

Date de publication:
20 09 2022
Historique:
pubmed: 31 8 2022
medline: 24 9 2022
entrez: 30 8 2022
Statut: ppublish

Résumé

The MOX lineage of β-lactamases includes a group of molecular class C enzymes (AmpCs) encoded by genes mobilized from the chromosomes of

Identifiants

DOI: 10.1128/aac.00595-22 PMID: 36040170 PMC: PMC9487596
pubmed: 36040170
doi: 10.1128/aac.00595-22
pmc: PMC9487596
doi:

Substances chimiques

Bacterial Proteins 0
Cephalosporins 0
Clavulanic Acid 23521W1S24
beta-Lactamases EC 3.5.2.6
Sulbactam S4TF6I2330
Tazobactam SE10G96M8W

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e0059522

Références

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Auteurs

Alessandra Piccirilli (A)

Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.
ORCID: 0000-0001-7560-5221

Alberto Antonelli (A)

Department of Experimental and Clinical Medicine, University of Florencegrid.8404.8, Florence, Italy.
Microbiology and Virology Unit, Careggi University Hospital, Florence, Italy.
ORCID: 0000-0003-0295-6877

Marco Maria D'Andrea (MM)

Department of Biology, University of Rome Tor Vergata, Rome, Italy.

Sabrina Cherubini (S)

Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.

Mariagrazia Perilli (M)

Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.
ORCID: 0000-0001-7370-1455

Gian Maria Rossolini (GM)

Department of Experimental and Clinical Medicine, University of Florencegrid.8404.8, Florence, Italy.
Microbiology and Virology Unit, Careggi University Hospital, Florence, Italy.
ORCID: 0000-0002-9386-0434

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Classifications MeSH

questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines bactériennes › Molecular and Kinetic Characterization of...
questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérobicycliques › bêta-Lactames › Céphalosporines › Molecular and Kinetic Characterization of...
questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérobicycliques › bêta-Lactames › Acides clavulaniques › Acide clavulanique › Molecular and Kinetic Characterization of...
questionsmedicales.fr › Phénomènes chimiques › Phénomènes biochimiques › Cinétique › Molecular and Kinetic Characterization of...
questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Plasmides › Molecular and Kinetic Characterization of...
questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérobicycliques › bêta-Lactames › Pénicillines › Sulbactam › Molecular and Kinetic Characterization of...
questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérobicycliques › bêta-Lactames › Pénicillines › Acide pénicillanique › Tazobactam › Molecular and Kinetic Characterization of...
questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Hydrolases › Amidohydrolases › bêta-Lactamases › Molecular and Kinetic Characterization of...