Biofabricating the vascular tree in engineered bone tissue.
Biofabrication
Bone tissue engineering
Tissue engineering
Vascularization
Journal
Acta biomaterialia
ISSN: 1878-7568
Titre abrégé: Acta Biomater
Pays: England
ID NLM: 101233144
Informations de publication
Date de publication:
15 01 2023
15 01 2023
Historique:
received:
28
04
2022
revised:
22
08
2022
accepted:
23
08
2022
pubmed:
31
8
2022
medline:
18
1
2023
entrez:
30
8
2022
Statut:
ppublish
Résumé
The development of tissue engineering strategies for treatment of large bone defects has become increasingly relevant, given the growing demand for bone substitutes. Native bone is composed of a dense vascular network necessary for the regulation of bone development, regeneration and homeostasis. A major obstacle in fabricating living, clinically relevant-sized bone mimics (1-10 cm
Identifiants
pubmed: 36041651
pii: S1742-7061(22)00528-1
doi: 10.1016/j.actbio.2022.08.051
pii:
doi:
Substances chimiques
Bone Substitutes
0
Types de publication
Journal Article
Review
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
250-268Informations de copyright
Copyright © 2022. Published by Elsevier Ltd.
Déclaration de conflit d'intérêts
Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.