Cyclic vomiting syndrome in children: a nationwide survey of current practice on behalf of the Italian Society of Pediatric Gastroenterology, Hepatology and Nutrition (SIGENP) and Italian Society of Pediatric Neurology (SINP).


Journal

Italian journal of pediatrics
ISSN: 1824-7288
Titre abrégé: Ital J Pediatr
Pays: England
ID NLM: 101510759

Informations de publication

Date de publication:
30 Aug 2022
Historique:
received: 16 03 2022
accepted: 10 08 2022
entrez: 30 8 2022
pubmed: 31 8 2022
medline: 2 9 2022
Statut: epublish

Résumé

Cyclic Vomiting Syndrome (CVS) is a rare functional gastrointestinal disorder, which has a considerable burden on quality of life of both children and their family. Aim of the study was to evaluate the diagnostic modalities and therapeutic approach to CVS among Italian tertiary care centers and the differences according to subspecialties, as well as to explore whether potential predictive factors associated with either a poor outcome or a response to a specific treatment. Cross-sectional multicenter web-based survey involving members of the Italian Society of Pediatric Gastroenterology, Hepatology and Nutrition (SIGENP) and Italian Society of Pediatric Neurology (SINP). A total of 67 responses were received and analyzed. Most of the respondent units cared for less than 20 patients. More than half of the patients were referred after 3 to 5 episodes, and a quarter after 5 attacks. We report different diagnostic approaches among Italian clinicians, which was particularly evident when comparing gastroenterologists and neurologists. Moreover, our survey demonstrated a predilection of certain drugs during emetic phase according to specific clinic, which reflects the cultural background of physicians. In conclusion, our survey highlights poor consensus amongst clinicians in our country in the diagnosis and the management of children with CVS, raising the need for a national consensus guideline in order to standardize the practice.

Sections du résumé

BACKGROUND BACKGROUND
Cyclic Vomiting Syndrome (CVS) is a rare functional gastrointestinal disorder, which has a considerable burden on quality of life of both children and their family. Aim of the study was to evaluate the diagnostic modalities and therapeutic approach to CVS among Italian tertiary care centers and the differences according to subspecialties, as well as to explore whether potential predictive factors associated with either a poor outcome or a response to a specific treatment.
METHODS METHODS
Cross-sectional multicenter web-based survey involving members of the Italian Society of Pediatric Gastroenterology, Hepatology and Nutrition (SIGENP) and Italian Society of Pediatric Neurology (SINP).
RESULTS RESULTS
A total of 67 responses were received and analyzed. Most of the respondent units cared for less than 20 patients. More than half of the patients were referred after 3 to 5 episodes, and a quarter after 5 attacks. We report different diagnostic approaches among Italian clinicians, which was particularly evident when comparing gastroenterologists and neurologists. Moreover, our survey demonstrated a predilection of certain drugs during emetic phase according to specific clinic, which reflects the cultural background of physicians.
CONCLUSION CONCLUSIONS
In conclusion, our survey highlights poor consensus amongst clinicians in our country in the diagnosis and the management of children with CVS, raising the need for a national consensus guideline in order to standardize the practice.

Identifiants

pubmed: 36042474
doi: 10.1186/s13052-022-01346-y
pii: 10.1186/s13052-022-01346-y
pmc: PMC9429644
doi:

Types de publication

Journal Article Multicenter Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

156

Informations de copyright

© 2022. The Author(s).

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Auteurs

Sara Isoldi (S)

Maternal and Child Health Department, Santa Maria Goretti Hospital, Sapienza-University of Rome, Latina, Italy.

Giovanni Di Nardo (G)

Department of Neuroscience, Mental Health and Sense Organs (NESMOS), Faculty of Medicine & Psychology, Sant'Andrea Hospital, Sapienza University of Rome, 00189, Rome, Lazio, Italy.

Saverio Mallardo (S)

Maternal and Child Health Department, Santa Maria Goretti Hospital, Sapienza-University of Rome, Latina, Italy.

Pasquale Parisi (P)

Department of Neuroscience, Mental Health and Sense Organs (NESMOS), Faculty of Medicine & Psychology, Sant'Andrea Hospital, Sapienza University of Rome, 00189, Rome, Lazio, Italy. pasquale.parisi@uniroma1.it.

Umberto Raucci (U)

Pediatric Emergency Department, Bambino Gesù Children's Hospital, Institute for Research, Hospitalization and Health Care (IRCCS), Rome, Italy.

Renato Tambucci (R)

Digestive Endoscopy and Surgery Unit, Bambino Gesù Children's Hospital, Institute for Research, Hospitalization and Health Care (IRCCS), Rome, Italy.

Paolo Quitadamo (P)

Department of Pediatrics, A.O.R.N. Santobono-Pausilipon, Naples, Italy.

Silvia Salvatore (S)

Pediatric Department, Ospedale "F. Del Ponte", University of Insubria, Varese, Italy.

Enrico Felici (E)

Unit of Pediatrics, The Children Hospital, Azienda Ospedaliera SS Antonio e Biagio e Cesare Arrigo, Alessandria, Italy.

Fabio Cisarò (F)

Pediatric Gastroenterology Unit, Regina Margherita Children's Hospital, Azienda Ospedaliera-Universitaria, Città della Salute e della Scienza di Torino, Turin, Italy.

Licia Pensabene (L)

Pediatric Unit, Department of Medical and Surgical Sciences, University "Magna Graecia" of Catanzaro, Catanzaro, Italy.

Claudia Banzato (C)

Department of Surgical Sciences, Dentistry, Gynecology and Pediatrics, Pediatric Division, University of Verona, Verona, Italy.

Caterina Strisciuglio (C)

Department of Woman, Child, General and Specialistic Surgery, University of Campania "Luigi Vanvitelli", Naples, Italy.

Claudio Romano (C)

Pediatric Gastroenterology Unit, Department of Human Pathology in Adulthood and Childhood "G. Barresi", University of Messina, Messina, Italy.

Patrizia Fusco (P)

Pediatric Unit, Montis Regalis Hospital, Mondovì, Cuneo, Italy.

Francesca Rigotti (F)

Department of Pediatrics, Bolzano Hospital, Bolzano, Italy.

Naire Sansotta (N)

Paediatric Hepatology, Gastroenterology and Transplantation, Hospital Papa Giovanni XXIII, Bergamo, Italy.

Silvia Caimmi (S)

Pediatric Clinic, Foundation IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy.

Salvatore Savasta (S)

Pediatric Clinic, Foundation IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy.

Giovanna Zuin (G)

Pediatric Department, University of Milano Bicocca, FMBBM, San Gerardo Hospital, Monza, Italy.

Marina Di Stefano (M)

Department of Pediatrics, IRCCS San Raffaele Scientific Institute, Milan, Italy.

Silvia Provera (S)

Department of Pediatrics, IRCCS Sacro Cuore Don Calabria Hospital, Negrar, Verona, Italy.

Angelo Campanozzi (A)

Department of Medical and Surgical Sciences, Pediatric Unit, University of Foggia, Foggia, Italy.

Paolo Rossi (P)

Department of Pediatrics, Pediatric Gastroenterology and Liver Unit, Sapienza University of Rome, Rome, Italy.

Simona Gatti (S)

Department of Pediatrics, Università Politecnica delle Marche, Ancona, Italy.

Mara Corpino (M)

Gastroenterologia Pediatrica, Clinica Pediatrica e Malattie Rare, Ospedale Pediatrico Microcitemico A. Cao, ARNAS Brotzu, Cagliari, Italy.

Patrizia Alvisi (P)

Department of Paediatrics, Ospedale Maggiore, Azienda USL, Bologna, Italy.

Stefano Martelossi (S)

Pediatric Unit, Ca' Foncello's Hospital, Treviso, Italy.

Agnese Suppiej (A)

Pediatric Section, Department of Medical Sciences, University of Ferrara, Ferrara, Italy.

Paolo Gandullia (P)

UOC Gastroenterologia, IRCCS Istituto Giannina Gaslini, Genoa, Italy.

Alberto Verrotti (A)

Department of Pediatrics, University of Perugia, Perugia, Italy.

Gianluca Terrin (G)

Department of Maternal and Child Health, Policlinico Umberto I, Sapienza University of Rome, Rome, Italy.

Caterina Pacenza (C)

Department of Pediatrics, San Giovanni di Dio Hospital, Crotone, Italy.

Fabiola Fornaroli (F)

Gastroenterology and Endoscopy Unit, Department of Medicine and Surgery, University of Parma, Parma, Italy.

Donatella Comito (D)

Ospedale Santa Croce, Moncalieri, Italy.

Stefano D'Arrigo (S)

Developmental Neurology Division, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.

Pasquale Striano (P)

Pediatric Neurology Unit, IRCCS Istituto Giannina Gaslini, Genoa, Italy.

Federico Raviglione (F)

Hospital Neuropsychiatry Service, ASST Rhodense, Rho, Milan, Italy.

Marco Carotenuto (M)

Clinic of Child and Adolescent Neuropsychiatry, Department of Mental Health and Physical and Preventive Medicine, Università degli Studi della Campania "Luigi Vanvitelli", Caserta, Italy.

Alessandro Orsini (A)

Paediatric Neurology Section, Paediatric Department, Pisa University Hospital, University of Pisa, Pisa, Italy.

Vincenzo Belcastro (V)

Neurology Unit, Maggiore Hospital, Lodi, Italy.

Giovanna Di Corcia (G)

Pediatric Department, "Augusto Murri" Hospital, Fermo, Italy.

Vincenzo Raieli (V)

Child Neuropsychiatry Unit - ISMEP- ARNAS CIVICO, Palermo, Italy.

Michela Ada Noris Ferilli (MAN)

Department of Neuroscience, Paediatric Headache Center, Bambino Gesù Children Hospital, IRCCS, Rome, Italy.

Claudia Ruscitto (C)

Child Neurology and Psychiatry Unit, Systems Medicine Department, Tor Vergata University Hospital of Rome, Rome, Italy.

Elisabetta Spadoni (E)

Pediatric Department, Azienda Ospedaliera Nord-Ovest of Tuscany, San Luca Hospital of Lucca, Lucca, Italy.

Salvatore Grosso (S)

Molecular Medicine and Development, University of Siena, Siena, Italy.

Renato D'Alonzo (R)

Pediatric and Neonatological Unit, Maternal and Child Department, Nuovo Ospedale San Giovanni Battista, Foligno, Italy.

Amanda Papa (A)

Infantile Neuropsychiatry Departement Maggiore della Carità University Hospital, Novara, Italy.

Piero Pavone (P)

Section of Pediatrics and Child Neuropsychiatry, Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy.

Mariaclaudia Meli (M)

Azienda Policlinico, "Rodolico-San Marco Hospital", University of Catania, Catania, Italy.

Mario Velardita (M)

Department of Pediatrics, Hospital "Salvatore e Saverio Gravina", Caltagirone, Italy.

Martina Mainetti (M)

Department of Pediatrics, Santa Maria delle Croci Hospital, Ravenna, Italy.

Nicola Vanacore (N)

National Centre for Epidemiology, Surveillance and Health Promotion, National Institute of Health, Rome, Italy.

Osvaldo Borrelli (O)

Division of Neurogastroenterology and Motility, Department of Pediatric Gastroenterology, University College London (UCL) Institute of Child Health and Great Ormond Street Hospital, London, UK.

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