Drug resistant bacteria in perianal abscesses are frequent and relevant.


Journal

Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288

Informations de publication

Date de publication:
01 09 2022
Historique:
received: 06 01 2022
accepted: 24 08 2022
entrez: 1 9 2022
pubmed: 2 9 2022
medline: 9 9 2022
Statut: epublish

Résumé

Perianal abscesses are frequent diseases in general surgery. Principles of standard patient care are surgical drainage with exploration and concomitant treatment of fistula. Antiinfective therapy is frequently applied in cases of severe local disease and perianal sepsis. However, the role of microbiologic testing of purulence from perianal abscesses is disputed and the knowledge concerning bacteriology and bacterial resistances is very limited. A retrospective cohort study was performed of consecutive patients (≥ 12 years of age) from a tertiary care hospital, who underwent surgical treatment for perianal abscess from 01/2008 to 12/2019. Subdividing the cohort into three groups regarding microbiological testing results: no microbiological testing of purulence (No_Swab, n = 456), no detection of drug resistant bacteria [DR(-), n = 141] or detection of bacteria with acquired drug resistances from purulence [DR(+), n = 220]. Group comparisons were performed using Kruskall-Wallis test and, if applicable, followed by Dunn´s multiple comparisons test for continuous variables or Fishers exact or Pearson's X

Identifiants

pubmed: 36050427
doi: 10.1038/s41598-022-19123-6
pii: 10.1038/s41598-022-19123-6
pmc: PMC9436980
doi:

Substances chimiques

Anti-Bacterial Agents 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

14866

Informations de copyright

© 2022. The Author(s).

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Auteurs

Fabienne Bender (F)

Department of General, Visceral, Thoracic, Transplant and Pediatric Surgery, University Hospital of Giessen, Rudolf-Buchheim Strasse 7, 35390, Giessen, Germany.

Lukas Eckerth (L)

Department of General, Visceral, Thoracic, Transplant and Pediatric Surgery, University Hospital of Giessen, Rudolf-Buchheim Strasse 7, 35390, Giessen, Germany.

Moritz Fritzenwanker (M)

Institute of Medical Microbiology, Justus-Liebig-University of Giessen, Schubertstrasse 81, 35392, Giessen, Germany.
German Center for Infection Research (DZIF), Site Giessen-Marburg-Langen, Justus-Liebig-University of Giessen, Schubertstrasse 81, 35392, Giessen, Germany.

Juliane Liese (J)

Department of General, Visceral, Thoracic, Transplant and Pediatric Surgery, University Hospital of Giessen, Rudolf-Buchheim Strasse 7, 35390, Giessen, Germany.

Ingolf Askevold (I)

Department of General, Visceral, Thoracic, Transplant and Pediatric Surgery, University Hospital of Giessen, Rudolf-Buchheim Strasse 7, 35390, Giessen, Germany.

Can Imirzalioglu (C)

Institute of Medical Microbiology, Justus-Liebig-University of Giessen, Schubertstrasse 81, 35392, Giessen, Germany.
German Center for Infection Research (DZIF), Site Giessen-Marburg-Langen, Justus-Liebig-University of Giessen, Schubertstrasse 81, 35392, Giessen, Germany.

Winfried Padberg (W)

Department of General, Visceral, Thoracic, Transplant and Pediatric Surgery, University Hospital of Giessen, Rudolf-Buchheim Strasse 7, 35390, Giessen, Germany.

Andreas Hecker (A)

Department of General, Visceral, Thoracic, Transplant and Pediatric Surgery, University Hospital of Giessen, Rudolf-Buchheim Strasse 7, 35390, Giessen, Germany.

Martin Reichert (M)

Department of General, Visceral, Thoracic, Transplant and Pediatric Surgery, University Hospital of Giessen, Rudolf-Buchheim Strasse 7, 35390, Giessen, Germany. martin.reichert@chiru.med.uni-giessen.de.

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