Trial of labor following cesarean in preterm deliveries: success rates and maternal and neonatal outcomes: a multicenter retrospective study.


Journal

Archives of gynecology and obstetrics
ISSN: 1432-0711
Titre abrégé: Arch Gynecol Obstet
Pays: Germany
ID NLM: 8710213

Informations de publication

Date de publication:
Sep 2023
Historique:
received: 08 04 2022
accepted: 12 08 2022
medline: 17 7 2023
pubmed: 7 9 2022
entrez: 6 9 2022
Statut: ppublish

Résumé

To evaluate the rates of vaginal birth after cesarean (VBAC) among parturients attempting preterm trial of labor following a cesarean delivery (TOLAC) vs. term TOLAC. A multicenter historic cohort study was conducted at two university-affiliated centers between August 2005 and March 2021. Parturients in their second delivery, attempting TOLAC after a single low segment transverse cesarean delivery were included. We retrospectively examined computerized medical records of all preterm (< 37 weeks) and term (37-42 weeks) births. Multifetal gestations and postterm deliveries (≥ 42 weeks) were excluded. A univariate analysis was conducted, followed by a multivariate analysis. 4865 second deliveries following previous cesarean were identified: 212 (4.4%) preterm and 4653 (95.6%) term. Hypertensive disorders, diabetes and fertility treatments were significantly more prevalent in the preterm group. VBAC rate was significantly lower in preterm group (57.5 vs 79.7%., p < 0.01), including both spontaneous and vaginal-assisted deliveries. In multivariate analysis, preterm TOLAC was independently associated with TOLAC failure [adjusted odds ratio 2.24, [95% confidence interval 1.62-3.09]. Overall, maternal outcomes were favorable. Rates of uterine rupture, re-laparotomy and postpartum hemorrhage were comparable between groups. Neonatal outcomes were less favorable among the preterm group; however, preterm vs. term TOLAC was not associated with low 5 min Apgar score (aOR 1.76, 95% CI 0.92-3.40). In our study, VBAC rates were lower in preterm compared to term deliveries. Maternal outcomes were comparable. Neonatal outcomes were less favorable in the preterm group, more likely due to prematurity than delivery mode.

Identifiants

pubmed: 36068361
doi: 10.1007/s00404-022-06746-3
pii: 10.1007/s00404-022-06746-3
doi:

Types de publication

Multicenter Study Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

863-870

Informations de copyright

© 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.

Références

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Auteurs

Reut Rotem (R)

Department of Obstetrics and Gynecology, Shaare Zedek Medical Center, Hebrew University Faculty of Medicine, POB 3235, 91031, Jerusalem, Israel.

Ayala Hirsch (A)

Department of Obstetrics and Gynecology, Shaare Zedek Medical Center, Hebrew University Faculty of Medicine, POB 3235, 91031, Jerusalem, Israel.

Moshe Barg (M)

Department of Obstetrics and Gynecology, Shaare Zedek Medical Center, Hebrew University Faculty of Medicine, POB 3235, 91031, Jerusalem, Israel.

Pnina Mor (P)

Department of Obstetrics and Gynecology, Shaare Zedek Medical Center, Hebrew University Faculty of Medicine, POB 3235, 91031, Jerusalem, Israel.
Medical Genetics Institute, Shaare Zedek Medical Center, Hebrew University Faculty of Medicine, Jerusalem, Israel.

Rachel Michaelson-Cohen (R)

Department of Obstetrics and Gynecology, Shaare Zedek Medical Center, Hebrew University Faculty of Medicine, POB 3235, 91031, Jerusalem, Israel. rachelmc@szmc.org.il.
Medical Genetics Institute, Shaare Zedek Medical Center, Hebrew University Faculty of Medicine, Jerusalem, Israel. rachelmc@szmc.org.il.

Misgav Rottenstreich (M)

Department of Obstetrics and Gynecology, Shaare Zedek Medical Center, Hebrew University Faculty of Medicine, POB 3235, 91031, Jerusalem, Israel.
Department of Nursing, Jerusalem College of Technology, Jerusalem, Israel.

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