Stable isotope ratios of nitrogen and carbon as biomarkers of a vegan diet.
Biomarkers
Dietary intake data.
Nitrogen isotopes
Stable isotope ratios
Vegan diet
δ13C
δ15N
Journal
European journal of nutrition
ISSN: 1436-6215
Titre abrégé: Eur J Nutr
Pays: Germany
ID NLM: 100888704
Informations de publication
Date de publication:
Feb 2023
Feb 2023
Historique:
received:
27
02
2022
accepted:
24
08
2022
pubmed:
11
9
2022
medline:
8
2
2023
entrez:
10
9
2022
Statut:
ppublish
Résumé
Dietary biomarkers can potentially overcome the limitations of self-reported dietary data. While in ecology and archaeology, stable isotope ratios of carbon and nitrogen are widely used as biomarkers, this is not the case in nutrition research. Since the abundance of the 13C and the 15N isotope differ in food sources from plant and animal origin, stable isotope ratios of carbon and nitrogen (δ13C and δ15N) may differ in human biological material. Here, we investigated the stable isotope ratios of nitrogen and carbon in serum and urine from vegans and omnivores. Measurement of δ15N and δ13C in serum and 24 h urine was performed by Elemental Analyzer-Isotope Ratio Mass Spectrometer in the cross-sectional study "Risks and Benefits of a Vegan Diet". The study included 36 vegans and 36 omnivores with a median age of 37.5 years (matched for age and sex), who adhered to their diet for at least 1 year. Both δ15N and δ13C were significantly lower in both the serum and 24 h urine of vegans compared to omnivores. δ15N either in serum or urine had 100% specificity and sensitivity to discriminate between vegans and omnivores. Specificity of δ13C was also > 90%, while sensitivity was 93% in serum and 77% in urine. δ15N both in serum and urine was able to accurately identify vegans and thus appears to be a promising marker for dietary habits.
Identifiants
pubmed: 36087137
doi: 10.1007/s00394-022-02992-y
pii: 10.1007/s00394-022-02992-y
pmc: PMC9899720
doi:
Substances chimiques
Nitrogen
N762921K75
Carbon
7440-44-0
Carbon Isotopes
0
Nitrogen Isotopes
0
Biomarkers
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
433-441Informations de copyright
© 2022. The Author(s).
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