Zoonotic Enterocytozoon bieneusi genotypes in free-ranging and farmed wild ungulates in Spain.
Enterocytozoon bieneusi
Spain
molecular diversity
wild ungulates
Journal
Medical mycology
ISSN: 1460-2709
Titre abrégé: Med Mycol
Pays: England
ID NLM: 9815835
Informations de publication
Date de publication:
30 Sep 2022
30 Sep 2022
Historique:
received:
29
06
2022
revised:
06
08
2022
accepted:
08
09
2022
pubmed:
13
9
2022
medline:
5
10
2022
entrez:
12
9
2022
Statut:
ppublish
Résumé
Microsporidia comprises a diverse group of obligate, intracellular, and spore-forming parasites that infect a wide range of animals. Among them, Enterocytozoon bieneusi is the most frequently reported species in humans and other mammals and birds. Data on the epidemiology of E. bieneusi in wildlife are limited. Hence, E. bieneusi was investigated in eight wild ungulate species present in Spain (genera Ammotragus, Capra, Capreolus, Cervus, Dama, Ovis, Rupicapra, and Sus) by molecular methods. Faecal samples were collected from free-ranging (n = 1058) and farmed (n = 324) wild ungulates from five Spanish bioregions. The parasite was detected only in red deer (10.4%, 68/653) and wild boar (0.8%, 3/359). Enterocytozoon bieneusi infections were more common in farmed (19.4%, 63/324) than in wild (1.5%, 5/329) red deer. A total of 11 genotypes were identified in red deer, eight known (BEB6, BEB17, EbCar2, HLJD-V, MWC_d1, S5, Type IV, and Wildboar3) and three novel (DeerSpEb1, DeerSpEb2, and DeerSpEb3) genotypes. Mixed genotype infections were detected in 15.9% of farmed red deer. Two genotypes were identified in wild boar, a known (Wildboar3) and a novel (WildboarSpEb1) genotypes. All genotypes identified belonged to E. bieneusi zoonotic Groups 1 and 2. This study provides the most comprehensive epidemiological study of E. bieneusi in Spanish ungulates to date, representing the first evidence of the parasite in wild red deer populations worldwide. Spanish wild boars and red deer are reservoir of zoonotic genotypes of E. bieneusi and might play an underestimated role in the transmission of this microsporidian species to humans and other animals. The fungal-related intracellular parasite Enterocytozoon bieneusi is a worldwide public health and veterinary problem. Here we demonstrated that it was present in wild boar, and wild and farmed red deer in Spain, with genotypes potentially capable of infecting humans, posing a public health risk.
Autres résumés
Type: plain-language-summary
(eng)
The fungal-related intracellular parasite Enterocytozoon bieneusi is a worldwide public health and veterinary problem. Here we demonstrated that it was present in wild boar, and wild and farmed red deer in Spain, with genotypes potentially capable of infecting humans, posing a public health risk.
Identifiants
pubmed: 36095135
pii: 6696380
doi: 10.1093/mmy/myac070
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Carlos III Health Institute
Organisme : Institute of Cosmos Sciences, University of Barcelona
ID : 13/051
Organisme : Ministry of Economy and Competitiveness
ID : CGL2012
Organisme : Spanish Ministry of Science and Innovation
ID : CGL2016-80543-P
Investigateurs
Carles Conejero
(C)
Carlos González-Crespo
(C)
Cristina Garrido
(C)
Diana Gassó
(D)
Diana Andrea Murillo
(D)
Emmanuel Serrano
(E)
Gregorio Mentaberre
(G)
Irene Torres-Blas
(I)
Josep Estruch
(J)
Josep Pastor
(J)
Jorge Ramón López-Olvera
(J)
María Escobar-González
(M)
Marta Valldeperes
(M)
Montse Mesalles
(M)
Omar López
(O)
Raquel Álvarez
(R)
Rafaela Cuenca
(R)
Roser Velarde
(R)
Santiago Lavín
(S)
Informations de copyright
© The Author(s) 2022. Published by Oxford University Press on behalf of The International Society for Human and Animal Mycology.