Green diatom mutants reveal an intricate biosynthetic pathway of fucoxanthin.
biosynthesis
diatoms
fucoxanthin
haptophytes
xanthophyll cycle
Journal
Proceedings of the National Academy of Sciences of the United States of America
ISSN: 1091-6490
Titre abrégé: Proc Natl Acad Sci U S A
Pays: United States
ID NLM: 7505876
Informations de publication
Date de publication:
20 09 2022
20 09 2022
Historique:
entrez:
12
9
2022
pubmed:
13
9
2022
medline:
15
9
2022
Statut:
ppublish
Résumé
Fucoxanthin is a major light-harvesting pigment in ecologically important algae such as diatoms, haptophytes, and brown algae (Phaeophyceae). Therefore, it is a major driver of global primary productivity. Species of these algal groups are brown colored because the high amounts of fucoxanthin bound to the proteins of their photosynthetic machineries enable efficient absorption of green light. While the structure of these fucoxanthin-chlorophyll proteins has recently been resolved, the biosynthetic pathway of fucoxanthin is still unknown. Here, we identified two enzymes central to this pathway by generating corresponding knockout mutants of the diatom
Identifiants
pubmed: 36095219
doi: 10.1073/pnas.2203708119
pmc: PMC9499517
doi:
Substances chimiques
Xanthophylls
0
fucoxanthin
06O0TC0VSM
Carotenoids
36-88-4
Types de publication
Journal Article
Research Support, U.S. Gov't, Non-P.H.S.
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e2203708119Références
Biochim Biophys Acta Bioenerg. 2020 Apr 1;1861(4):148027
pubmed: 31153887
J Biol Chem. 2002 Oct 4;277(40):36913-20
pubmed: 12114527
PLoS One. 2008 Aug 06;3(8):e2896
pubmed: 18682837
Nat Commun. 2014 Dec 10;5:5764
pubmed: 25493338
PLoS Biol. 2014 Jun 24;12(6):e1001889
pubmed: 24959919
Mar Drugs. 2015 Sep 16;13(9):5847-81
pubmed: 26389924
Proc Natl Acad Sci U S A. 1999 Jul 20;96(15):8784-9
pubmed: 10411953
Planta. 2001 Feb;212(3):382-91
pubmed: 11289603
Syst Biol. 2008 Oct;57(5):758-71
pubmed: 18853362
ACS Synth Biol. 2018 Feb 16;7(2):328-338
pubmed: 29298053
Acc Chem Res. 2010 Aug 17;43(8):1125-34
pubmed: 20446691
Annu Rev Plant Physiol Plant Mol Biol. 1999 Jun;50:47-65
pubmed: 15012203
Mol Biol Evol. 2008 Dec;25(12):2653-67
pubmed: 18799712
Proc Natl Acad Sci U S A. 2009 Aug 4;106(31):12803-8
pubmed: 19622724
Sci Adv. 2020 Mar 04;6(10):eaaw9183
pubmed: 32181334
J Eukaryot Microbiol. 2019 Jan;66(1):4-119
pubmed: 30257078
PeerJ. 2018 Nov 14;6:e5884
pubmed: 30488015
Protein Sci. 1999 May;8(5):978-84
pubmed: 10338008
Nat Plants. 2019 Aug;5(8):890-901
pubmed: 31358960
Bioinformatics. 2014 May 1;30(9):1312-3
pubmed: 24451623
J Mol Biol. 2004 Jul 16;340(4):783-95
pubmed: 15223320
J Plant Physiol. 2016 Mar 15;192:64-70
pubmed: 26851888
Genome Biol Evol. 2014 Mar;6(3):666-84
pubmed: 24572015
Nat Methods. 2011 Sep 29;8(10):785-6
pubmed: 21959131
Nucleic Acids Res. 2003 Jul 1;31(13):3497-500
pubmed: 12824352
Annu Rev Plant Biol. 2008;59:491-517
pubmed: 18315522
Biochemistry. 2005 Mar 15;44(10):4028-36
pubmed: 15751979
Syst Biol. 2012 Dec 1;61(6):1061-7
pubmed: 22780991
Sci Rep. 2016 Apr 25;6:24951
pubmed: 27108533
Plant Mol Biol. 1994 Sep;25(6):989-94
pubmed: 7919218
Biochim Biophys Acta. 2012 Jan;1817(1):167-81
pubmed: 21569757
Nucleic Acids Res. 2018 Jul 2;46(W1):W242-W245
pubmed: 29762716
Funct Plant Biol. 2009 Jan;36(1):20-36
pubmed: 32688624
Proc Natl Acad Sci U S A. 2015 Aug 18;112(33):10247-54
pubmed: 25995366
Nat Commun. 2019 Sep 13;10(1):4167
pubmed: 31519883
Nucleic Acids Res. 1998 May 15;26(10):2508-10
pubmed: 9580709
Mol Biol Evol. 2001 May;18(5):691-9
pubmed: 11319253
Science. 1998 Jul 10;281(5374):237-40
pubmed: 9657713
Arch Biochem Biophys. 1978 Oct;190(2):514-22
pubmed: 102251
Nat Commun. 2020 Oct 8;11(1):5081
pubmed: 33033236
J Sci Food Agric. 2013 Jan 15;93(1):5-11
pubmed: 23044813
Proc Natl Acad Sci U S A. 1996 Jun 25;93(13):6320-5
pubmed: 8692813
J Exp Bot. 2012 Sep;63(15):5607-12
pubmed: 22888128
J Phys Chem B. 2009 Sep 17;113(37):12565-74
pubmed: 19697894
Antioxidants (Basel). 2019 Nov 16;8(11):
pubmed: 31744163
Proc Natl Acad Sci U S A. 2016 Mar 15;113(11):E1516-25
pubmed: 26929361
BMC Plant Biol. 2015 Feb 04;15:34
pubmed: 25648715
Science. 2019 Aug 2;365(6452):
pubmed: 31371578
Plant J. 2007 Jun;50(5):810-24
pubmed: 17470058
Science. 2015 May 22;348(6237):1261605
pubmed: 25999516
Ann Rev Mar Sci. 2020 Jan 3;12:233-265
pubmed: 31899671
Science. 2019 Feb 8;363(6427):
pubmed: 30733387
Photosynth Res. 2010 Nov;106(1-2):103-22
pubmed: 20224940
Mar Genomics. 2014 Aug;16:63-6
pubmed: 24269346
Nucleic Acids Res. 1997 Sep 1;25(17):3389-402
pubmed: 9254694
EMBO J. 1996 May 15;15(10):2331-42
pubmed: 8665840
Nat Commun. 2015 Apr 21;6:6925
pubmed: 25897682
PLoS One. 2010 Sep 16;5(9):
pubmed: 20862282
Protist. 2012 Mar;163(2):217-31
pubmed: 22001261
Annu Rev Plant Biol. 2021 Jun 17;72:47-76
pubmed: 34143647
Plant J. 2017 Dec;92(5):879-891
pubmed: 28949044
Antioxidants (Basel). 2017 Nov 23;6(4):
pubmed: 29168774
Plant J. 2015 May;82(4):582-95
pubmed: 25759133
Sci Rep. 2018 Sep 26;8(1):14401
pubmed: 30258061
PLoS One. 2014 Mar 03;9(3):e90372
pubmed: 24595202
Mar Drugs. 2021 Sep 23;19(10):
pubmed: 34677429
Genome Biol Evol. 2020 Jul 1;12(7):978-990
pubmed: 32402068
FEBS Lett. 1995 Nov 27;376(1-2):45-8
pubmed: 8521963
J Biosci Bioeng. 2019 Dec;128(6):755-765
pubmed: 31277909
Comput Appl Biosci. 1996 Aug;12(4):357-8
pubmed: 8902363
Mol Gen Genet. 1996 Oct 16;252(5):572-9
pubmed: 8914518