Roles and therapeutic potential of CD1d-Restricted NKT cells in inflammatory skin diseases.

CD1d-restricted NKT cells UV-induced skin inflammation allergic contact dermatitis atopic dermatitis glycolipid antigens psoriasis

Journal

Frontiers in immunology
ISSN: 1664-3224
Titre abrégé: Front Immunol
Pays: Switzerland
ID NLM: 101560960

Informations de publication

Date de publication:
2022
Historique:
received: 27 06 2022
accepted: 29 07 2022
entrez: 19 9 2022
pubmed: 20 9 2022
medline: 21 9 2022
Statut: epublish

Résumé

Natural killer T (NKT) cells are innate-like T lymphocytes that recognize glycolipid antigens rather than peptides. Due to their immunoregulatory properties, extensive work has been done to elucidate the immune functions of NKT cells in various immune contexts such as autoimmunity for more than two decades. In addition, as research on barrier immunity such as the mucosa-associated lymphoid tissue has flourished in recent years, the role of NKT cells to immunity in the skin has attracted substantial attention. Here, we review the contributions of NKT cells to regulating skin inflammation and discuss the factors that can modulate the functions of NKT cells in inflammatory skin diseases such as atopic dermatitis. This mini-review article will mainly focus on CD1d-dependent NKT cells and their therapeutic potential in skin-related immune diseases.

Identifiants

pubmed: 36119077
doi: 10.3389/fimmu.2022.979370
pmc: PMC9478174
doi:

Substances chimiques

Glycolipids 0
Peptides 0

Types de publication

Journal Article Review Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

979370

Informations de copyright

Copyright © 2022 Lee, Park, Van Kaer and Hong.

Déclaration de conflit d'intérêts

LVK is a member of the scientific advisory board of Isu Abxis Co., Ltd. (South Korea). The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Références

Cytotherapy. 2018 Sep;20(9):1155-1163
pubmed: 30100374
J Biomed Mater Res B Appl Biomater. 2019 Jul;107(5):1384-1392
pubmed: 30281908
Nat Immunol. 2010 Sep;11(9):814-9
pubmed: 20711192
J Invest Dermatol. 2021 Jun;141(6):1512-1521
pubmed: 33186589
Eur J Immunol. 2011 Jul;41(7):1913-23
pubmed: 21590763
J Invest Dermatol. 2004 Dec;123(6):1030-6
pubmed: 15610510
J Invest Dermatol. 1999 Feb;112(2):249-53
pubmed: 9989804
Cell Metab. 2020 Aug 4;32(2):243-258.e6
pubmed: 32516575
Arch Dermatol Res. 2005 Jul;297(1):18-25
pubmed: 15912415
Immunity. 2015 Sep 15;43(3):566-78
pubmed: 26362265
Clin Exp Immunol. 2002 Jan;127(1):176-82
pubmed: 11882050
Australas J Dermatol. 2016 May;57(2):122-7
pubmed: 26172088
J Invest Dermatol. 2013 Apr;133(4):980-7
pubmed: 23190881
Trends Immunol. 2009 Feb;30(2):67-74
pubmed: 19138566
Sci Rep. 2020 Mar 19;10(1):5050
pubmed: 32193426
Cell Immunol. 2013 Jul-Aug;284(1-2):163-71
pubmed: 23978680
Front Immunol. 2018 Mar 13;9:519
pubmed: 29593743
J Immunol. 2010 Oct 15;185(8):4633-40
pubmed: 20844203
Cell Host Microbe. 2017 Nov 8;22(5):653-666.e5
pubmed: 29120743
Front Immunol. 2017 Jul 21;8:848
pubmed: 28785267
J Immunol. 2009 Jun 15;182(12):7644-54
pubmed: 19494288
Arthritis Res Ther. 2019 Oct 15;21(1):212
pubmed: 31615552
Front Immunol. 2020 Nov 18;11:610010
pubmed: 33312179
Front Cell Dev Biol. 2022 Feb 03;9:799560
pubmed: 35186952
Cytotherapy. 2022 May;24(5):482-488
pubmed: 35181242
J Autoimmun. 2018 Jul;91:61-72
pubmed: 29680372
Front Immunol. 2015 May 13;6:226
pubmed: 26029211
Sci Rep. 2018 May 29;8(1):8225
pubmed: 29844470
Arch Dermatol Res. 2002 Nov;294(8):363-9
pubmed: 12420105
Am J Pathol. 2015 Dec;185(12):3248-57
pubmed: 26468976
Sci Rep. 2017 Jul 25;7(1):6470
pubmed: 28744000
Infect Immun. 2013 Apr;81(4):1114-20
pubmed: 23340309
J Invest Dermatol. 2008 Sep;128(9):2190-7
pubmed: 18385757
Pigment Cell Melanoma Res. 2012 Sep;25(5):602-11
pubmed: 22591262
Nat Immunol. 2016 Dec;17(12):1407-1414
pubmed: 27798616
Br J Dermatol. 2006 Oct;155(4):680-7
pubmed: 16965415
J Clin Immunol. 2011 Oct;31(5):864-72
pubmed: 21691938
J Allergy Clin Immunol. 2019 Apr;143(4):1355-1370.e16
pubmed: 30316823
J Immunol. 2006 Sep 15;177(6):3686-94
pubmed: 16951328
Nat Immunol. 2012 Jul 19;13(8):705-6
pubmed: 22814339
Hum Immunol. 2003 Jun;64(6):586-92
pubmed: 12770788
J Allergy Clin Immunol. 2019 Feb;143(2):565-576.e7
pubmed: 29852257
Contact Dermatitis. 2014 Oct;71(4):224-32
pubmed: 25040758
Clin Immunol. 2001 Aug;100(2):144-8
pubmed: 11465942
Int J Dermatol. 2020 Mar;59(3):359-364
pubmed: 31631342
Nat Immunol. 2011 Oct 30;12(12):1202-11
pubmed: 22037601
Annu Rev Immunol. 2020 Apr 26;38:171-202
pubmed: 32340577
J Invest Dermatol. 2014 Jan;134(1):192-202
pubmed: 23867896
Biomed Pharmacother. 2022 Mar;147:112633
pubmed: 35030434
J Dermatol Sci. 2000 Dec;24(3):212-25
pubmed: 11084303
Allergy. 2000 Jun;55(6):551-5
pubmed: 10858986
Exp Dermatol. 2012 Dec;21(12):915-20
pubmed: 23171451
PLoS One. 2016 Apr 11;11(4):e0153347
pubmed: 27064277
J Immunol. 2007 Feb 1;178(3):1415-25
pubmed: 17237389
Int Immunol. 2005 Dec;17(12):1619-29
pubmed: 16291659
Front Immunol. 2018 Nov 14;9:2653
pubmed: 30487800
Immunobiology. 2003;208(4):367-80
pubmed: 14748510
Int J Mol Sci. 2021 Apr 10;22(8):
pubmed: 33920301
J Immunol. 2009 Apr 15;182(8):5116-22
pubmed: 19342692
J Invest Dermatol. 2008 Jun;128(6):1460-9
pubmed: 18079745
Crit Rev Immunol. 2021;41(4):55-88
pubmed: 35381143
Immune Netw. 2018 Feb 26;18(1):e15
pubmed: 29503745
J Leukoc Biol. 2014 Jul;96(1):49-54
pubmed: 24799605
J Allergy Clin Immunol. 2010 Aug;126(2):290-9, 299.e1-4
pubmed: 20624642
Cell Rep. 2019 Mar 5;26(10):2681-2691.e5
pubmed: 30840890
Immunol Cell Biol. 2012 Aug;90(7):699-709
pubmed: 22041925
PLoS One. 2012;7(8):e41038
pubmed: 22916101
Nat Immunol. 2003 Dec;4(12):1230-7
pubmed: 14578883
Sci Rep. 2018 Jul 4;8(1):10081
pubmed: 29973666
Allergy. 2000 Mar;55(3):286-90
pubmed: 10753021
Exp Dermatol. 2015 Nov;24(11):853-6
pubmed: 26121177
Br J Dermatol. 2012 Apr;166(4):789-96
pubmed: 22233261
Expert Rev Clin Immunol. 2017 Jan;13(1):15-26
pubmed: 27417220
Sci Rep. 2017 Nov 2;7(1):14940
pubmed: 29097726
Nat Immunol. 2000 Dec;1(6):521-5
pubmed: 11101875
J Invest Dermatol. 2015 Jul;135(7):1771-1780
pubmed: 25739051
J Allergy Clin Immunol. 2021 May;147(5):1764-1777
pubmed: 33516870
Exp Dermatol. 2005 Apr;14(4):250-8
pubmed: 15810882
Nat Immunol. 2015 Aug;16(8):799-800
pubmed: 26075912
Clin Exp Immunol. 2000 Mar;119(3):404-11
pubmed: 10691910
J Clin Invest. 2011 Jan;121(1):57-69
pubmed: 21157038
Immunity. 2010 Aug 27;33(2):216-28
pubmed: 20727792
Sci Rep. 2019 Nov 21;9(1):17274
pubmed: 31754156
Chembiochem. 2006 Nov;7(11):1750-6
pubmed: 17009272
Front Immunol. 2021 Dec 15;12:788940
pubmed: 34975883
Biochim Biophys Acta Mol Cell Biol Lipids. 2020 Jun;1865(6):158673
pubmed: 32092464
Wound Repair Regen. 2017 Sep;25(5):805-815
pubmed: 28940971
Am J Pathol. 2004 Sep;165(3):879-87
pubmed: 15331412
Eur J Pharm Biopharm. 2016 Mar;100:101-8
pubmed: 26792104
J Immunol. 2000 Oct 1;165(7):4076-85
pubmed: 11034419
Biomedicines. 2021 Nov 04;9(11):
pubmed: 34829848
Arch Dermatol. 1999 May;135(5):546-52
pubmed: 10328195
Proc Natl Acad Sci U S A. 2014 Sep 16;111(37):13433-8
pubmed: 25197085
Skinmed. 2007 Sep-Oct;6(5):218-20
pubmed: 17786098
Cell Res. 2010 Apr;20(4):480-91
pubmed: 20084083

Auteurs

Sung Won Lee (SW)

Department of Integrative Bioscience and Biotechnology, Institute of Anticancer Medicine Development, Sejong University, Seoul, South Korea.

Hyun Jung Park (HJ)

Department of Integrative Bioscience and Biotechnology, Institute of Anticancer Medicine Development, Sejong University, Seoul, South Korea.

Luc Van Kaer (L)

Department of Pathology, Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, TN, United States.

Seokmann Hong (S)

Department of Integrative Bioscience and Biotechnology, Institute of Anticancer Medicine Development, Sejong University, Seoul, South Korea.

Articles similaires

Animals Natural Killer T-Cells Mice Adipose Tissue Lipid Metabolism
Animals Huntington Disease Mitochondria Neurons Mice
Animals Adjuvants, Immunologic Mice Antigen-Presenting Cells Antigen Presentation
Hemolysin Proteins Artificial Cells Protein Engineering Protein Transport Cell Membrane

Classifications MeSH