The serotonin receptor 3E variant is a risk factor for female IBS-D.

Humans Female Irritable Bowel Syndrome / genetics Serotonin Receptors, Serotonin / genetics Genotype Risk Factors Multicenter Studies as Topic
Females IBS-D Irritable bowel syndrome Serotonin type 3 receptor

Journal

Journal of molecular medicine (Berlin, Germany)
ISSN: 1432-1440
Titre abrégé: J Mol Med (Berl)
Pays: Germany
ID NLM: 9504370

Informations de publication

Date de publication:
11 2022
Historique:
received: 28 06 2021
accepted: 04 08 2022
revised: 18 07 2022
pubmed: 20 9 2022
medline: 27 10 2022
entrez: 19 9 2022
Statut: ppublish

Résumé

Irritable bowel syndrome (IBS) is a gut-brain disorder of multifactorial origin. Evidence of disturbed serotonergic function in IBS accumulated for the 5-HT

Identifiants

DOI: 10.1007/s00109-022-02244-w PMID: 36121467 PMC: PMC9592668
pubmed: 36121467
doi: 10.1007/s00109-022-02244-w
pii: 10.1007/s00109-022-02244-w
pmc: PMC9592668
doi:

Substances chimiques

Serotonin 333DO1RDJY
Receptors, Serotonin 0

Types de publication

Meta-Analysis Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1617-1627

Informations de copyright

© 2022. The Author(s).

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Auteurs

Nikola Fritz (N)

Institute of Human Genetics, Department of Human Molecular Genetics, Heidelberg University Hospital, Heidelberg, Germany.

Sabrina Berens (S)

Department of General Internal Medicine and Psychosomatics, Heidelberg University Hospital, Heidelberg, Germany.

Yuanjun Dong (Y)

Institute of Human Genetics, Department of Human Molecular Genetics, Heidelberg University Hospital, Heidelberg, Germany.

Cristina Martínez (C)

Institute of Human Genetics, Department of Human Molecular Genetics, Heidelberg University Hospital, Heidelberg, Germany.
Institut de Recerca Biomèdica de Lleida (IRBLleida), Lleida, Spain.
Lleida Institute for Biomedical Research Dr, Pifarré Foundation (IRBLleida), Lleida, Spain.

Stefanie Schmitteckert (S)

Institute of Human Genetics, Department of Human Molecular Genetics, Heidelberg University Hospital, Heidelberg, Germany. Stefanie.Schmitteckert@med.uni-heidelberg.de.

Lesley A Houghton (LA)

University of Leeds, St. James's University Hospital, Leeds, UK.
Mayo Clinic, Jacksonville, FL, USA.

Miriam Goebel-Stengel (M)

Department of Psychosomatic Medicine, University Hospital Tübingen, Tübingen, Germany.
Department of Internal Medicine and Gastroenterology, HELIOS Clinic Rottweil, Rottweil, Germany.

Verena Wahl (V)

Institute of Human Genetics, Department of Human Molecular Genetics, Heidelberg University Hospital, Heidelberg, Germany.

Maria Kabisch (M)

Institute of Medical Biometry and Informatics, Heidelberg University, Heidelberg, Germany.

Dorothea Götze (D)

Institute of Human Genetics, Department of Human Molecular Genetics, Heidelberg University Hospital, Heidelberg, Germany.

Mauro D'Amato (M)

Unit of Clinical Epidemiology, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.
Gastrointestinal Genetics Lab, CIC bioGUNE - BRTA, Bilbao, Derio, Spain.
IKERBASQUE, Basque Foundation for Science, Bilbao, Spain.

Tenghao Zheng (T)

Unit of Clinical Epidemiology, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.

Ralph Röth (R)

Institute of Human Genetics, Department of Human Molecular Genetics, Heidelberg University Hospital, Heidelberg, Germany.
nCounter Core Facility, Department of Human Molecular Genetics, Heidelberg University Hospital, Heidelberg, Germany.

Hubert Mönnikes (H)

Martin-Luther-Hospital, Berlin, Germany.

Jonas Tesarz (J)

Department of General Internal Medicine and Psychosomatics, Heidelberg University Hospital, Heidelberg, Germany.

Felicitas Engel (F)

Department of General Internal Medicine and Psychosomatics, Heidelberg University Hospital, Heidelberg, Germany.

Annika Gauss (A)

Department of Gastroenterology, Infectious Diseases and Intoxications, Heidelberg University, Heidelberg, Germany.

Martin Raithel (M)

University of Erlangen, Erlangen, Germany.

Viola Andresen (V)

Israelitisches Krankenhaus, Hamburg, Germany.

Jutta Keller (J)

Israelitisches Krankenhaus, Hamburg, Germany.

Thomas Frieling (T)

Helios Klinik Krefeld, Krefeld, Germany.

Christian Pehl (C)

Krankenhaus Vilsbiburg, Vilsbiburg, Germany.

Christoph Stein-Thöringer (C)

German Cancer Research Center, Heidelberg, Germany.

Gerard Clarke (G)

Department of Psychiatry and Neurobehavioral Science, University College Cork, Cork, Ireland.
APC Microbiome Ireland, University College Cork, Cork, Ireland.

Paul J Kennedy (PJ)

Department of Psychiatry and Neurobehavioral Science, University College Cork, Cork, Ireland.
APC Microbiome Ireland, University College Cork, Cork, Ireland.

John F Cryan (JF)

Department of Psychiatry and Neurobehavioral Science, University College Cork, Cork, Ireland.
APC Microbiome Ireland, University College Cork, Cork, Ireland.
Department of Anatomy and Neuroscience, University College Cork, Cork, Ireland.

Timothy G Dinan (TG)

Department of Psychiatry and Neurobehavioral Science, University College Cork, Cork, Ireland.
APC Microbiome Ireland, University College Cork, Cork, Ireland.

Eamonn M M Quigley (EMM)

APC Microbiome Ireland, University College Cork, Cork, Ireland.
Lynda K. and David M. Underwood Center for Digestive Disorders, Houston Methodist Hospital, Weill Cornell Medical College, Houston, TX, USA.

Robin Spiller (R)

Nottingham Digestive Diseases Centre, University of Nottingham, Nottingham, UK.

Caroll Beltrán (C)

Gastroenterology Unit, Medicine Department, Hospital Clínico Universidad de Chile, Universidad de Chile, Santiago de Chile, Chile.

Ana María Madrid (AM)

Gastroenterology Unit, Medicine Department, Hospital Clínico Universidad de Chile, Universidad de Chile, Santiago de Chile, Chile.

Verónica Torres (V)

Gastroenterology Unit, Medicine Department, Hospital Clínico Universidad de Chile, Universidad de Chile, Santiago de Chile, Chile.

Emeran A Mayer (EA)

Oppenheimer Center for Neurobiology of Stress, University of California, Los Angeles, CA, USA.

Gregory Sayuk (G)

Washington University School of Medicine, St. Louis, MO, USA.

Maria Gazouli (M)

Laboratory of Biology, Medical School, National and Kapodistrian University of Athens, Athens, Greece.

George Karamanolis (G)

Academic Department of Gastroenterology, Medical School, National and Kapodistrian University of Athens, Laikon General Hospital, Athens, Greece.

Mariona Bustamante (M)

CRG, Centre for Genomic Regulation, Barcelona, Spain.
ISGlobal, Barcelona, Spain.

Xavier Estivil (X)

Department of Genetics, Microbiology and Statistics, Faculty of Biology, IBUB, Universitat de Barcelona, CIBERER, IRSJD, Barcelona, Spain.

Raquel Rabionet (R)

Department of Genetics, Microbiology and Statistics, Faculty of Biology, IBUB, Universitat de Barcelona, CIBERER, IRSJD, Barcelona, Spain.

Per Hoffmann (P)

Life and Brain Center, Bonn, Germany.

Markus M Nöthen (MM)

Life and Brain Center, Bonn, Germany.

Stefanie Heilmann-Heimbach (S)

Life and Brain Center, Bonn, Germany.

Börge Schmidt (B)

Institute for Medical Informatics, Biometry and Epidemiology, University Hospital of Essen, Essen, Germany.

André Franke (A)

Institute of Clinical Molecular Biology, Kiel, Germany.

Wolfgang Lieb (W)

Institute of Epidemiology, Kiel, Germany.

Wolfgang Herzog (W)

Department of General Internal Medicine and Psychosomatics, Heidelberg University Hospital, Heidelberg, Germany.

Guy Boeckxstaens (G)

TARGID, University Hospital Leuven, Louvain, Belgium.

Mira M Wouters (MM)

TARGID, University Hospital Leuven, Louvain, Belgium.

Magnus Simrén (M)

Institute of Medicine, University of Gothenburg, Gothenburg, Sweden.

Gudrun A Rappold (GA)

Institute of Human Genetics, Department of Human Molecular Genetics, Heidelberg University Hospital, Heidelberg, Germany.
Interdisciplinary Center for Neurosciences (IZN), Heidelberg University, Heidelberg, Germany.

Maria Vicario (M)

Institut de Recerca Vall d Hebron, Hospital Vall d Hebron, Passeig de la Vall d Hebron, Barcelona, Spain.
Nestlé Institute of Health Sciences, Nestlé Research, Société Des Produits Nestlé S.A, Vers-chez-les-Blanc, Lausanne, Switzerland.

Javier Santos (J)

Institut de Recerca Vall d Hebron, Hospital Vall d Hebron, Passeig de la Vall d Hebron, Barcelona, Spain.

Rainer Schaefert (R)

Department of Psychosomatic Medicine, Division of Theragnostics, University Hospital Basel, Basel, Switzerland.
Faculty of Medicine, University of Basel, Basel, Switzerland.

Justo Lorenzo-Bermejo (J)

Institute of Medical Biometry and Informatics, Heidelberg University, Heidelberg, Germany.

Beate Niesler (B)

Institute of Human Genetics, Department of Human Molecular Genetics, Heidelberg University Hospital, Heidelberg, Germany.
nCounter Core Facility, Department of Human Molecular Genetics, Heidelberg University Hospital, Heidelberg, Germany.
Interdisciplinary Center for Neurosciences (IZN), Heidelberg University, Heidelberg, Germany.
ORCID: 0000-0001-7881-6112

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › The serotonin receptor 3E variant is a risk...
questionsmedicales.fr › Maladies de l'appareil digestif › Maladies gastro-intestinales › Maladies intestinales › Maladies du côlon › Troubles fonctionnels du côlon › Syndrome du côlon irritable › The serotonin receptor 3E variant is a risk...
questionsmedicales.fr › Facteurs biologiques › Médiateurs de l'inflammation › Autacoïdes › Sérotonine › The serotonin receptor 3E variant is a risk...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs aux neuromédiateurs › Récepteurs sérotoninergiques › The serotonin receptor 3E variant is a risk...
questionsmedicales.fr › Phénomènes génétiques › Génotype › The serotonin receptor 3E variant is a risk...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Statistiques comme sujet › Probabilité › Risque › Facteurs de risque › The serotonin receptor 3E variant is a risk...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études multicentriques comme sujet › The serotonin receptor 3E variant is a risk...