Cerebellar Prediction and Feeding Behaviour.
Cerebellum
Feeding behaviour
Hunger
Reward
Satiation
Journal
Cerebellum (London, England)
ISSN: 1473-4230
Titre abrégé: Cerebellum
Pays: United States
ID NLM: 101089443
Informations de publication
Date de publication:
Oct 2023
Oct 2023
Historique:
accepted:
01
09
2022
medline:
8
9
2023
pubmed:
20
9
2022
entrez:
19
9
2022
Statut:
ppublish
Résumé
Given the importance of the cerebellum in controlling movements, it might be expected that its main role in eating would be the control of motor elements such as chewing and swallowing. Whilst such functions are clearly important, there is more to eating than these actions, and more to the cerebellum than motor control. This review will present evidence that the cerebellum contributes to homeostatic, motor, rewarding and affective aspects of food consumption.Prediction and feedback underlie many elements of eating, as food consumption is influenced by expectation. For example, circadian clocks cause hunger in anticipation of a meal, and food consumption causes feedback signals which induce satiety. Similarly, the sight and smell of food generate an expectation of what that food will taste like, and its actual taste will generate an internal reward value which will be compared to that expectation. Cerebellar learning is widely thought to involve feed-forward predictions to compare expected outcomes to sensory feedback. We therefore propose that the overarching role of the cerebellum in eating is to respond to prediction errors arising across the homeostatic, motor, cognitive, and affective domains.
Identifiants
pubmed: 36121552
doi: 10.1007/s12311-022-01476-3
pii: 10.1007/s12311-022-01476-3
pmc: PMC10485105
mid: EMS181513
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
1002-1019Subventions
Organisme : Biotechnology and Biological Sciences Research Council
ID : BB/R017336/1
Pays : United Kingdom
Organisme : Biotechnology and Biological Sciences Research Council
ID : BB/M009122/1
Pays : United Kingdom
Informations de copyright
© 2022. Crown.
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