A microfluidic electrochemical sensing platform for
Journal
Analytical methods : advancing methods and applications
ISSN: 1759-9679
Titre abrégé: Anal Methods
Pays: England
ID NLM: 101519733
Informations de publication
Date de publication:
06 Oct 2022
06 Oct 2022
Historique:
pubmed:
21
9
2022
medline:
12
10
2022
entrez:
20
9
2022
Statut:
epublish
Résumé
Among various detection and analysis platforms, a microfluidic chip-based electrochemical sensing detection platform is a new type of detection platform. In this study, a microfluidic electrochemical detection platform for cadmium ion detection is proposed, and the performance of the detection platform is optimized in terms of both the microchannel size and electrode modifications. The detection mixing processes of the detector with different microchannel sizes, including the concentration distribution in the channel, pressure decay variation and electrolyte current density variation in the detector, were investigated by finite element model calculations. The analysis shows that the size of the microchannel in the detector affects the fluid and thus further affects the chemical reaction. If the size of the electrode does not match the size of the microchannel, insufficient sample volume will lead to inaccurate measurements, reduced sensitivity and increased detection limits. It was found that the sensitivity of the electrochemical sensor was highest when the size of the microchannel in the chip was 400 μm. After optimization, the optimal detection limit for cadmium ions was 0.03 μg L
Substances chimiques
Ions
0
Metals, Heavy
0
Cadmium
00BH33GNGH
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
3802-3813Commentaires et corrections
Type : ErratumIn