A microcircuit model involving parvalbumin, somatostatin, and vasoactive intestinal polypeptide inhibitory interneurons for the modulation of neuronal oscillation during visual processing.
computational model
inhibitory interneuron subtypes
neuronal oscillation
primary visual cortex
selective attention
Journal
Cerebral cortex (New York, N.Y. : 1991)
ISSN: 1460-2199
Titre abrégé: Cereb Cortex
Pays: United States
ID NLM: 9110718
Informations de publication
Date de publication:
04 04 2023
04 04 2023
Historique:
received:
03
04
2022
revised:
06
08
2022
accepted:
08
08
2022
medline:
19
4
2023
pubmed:
22
9
2022
entrez:
21
9
2022
Statut:
ppublish
Résumé
Various subtypes of inhibitory interneurons contact one another to organize cortical networks. Most cortical inhibitory interneurons express 1 of 3 genes: parvalbumin (PV), somatostatin (SOM), or vasoactive intestinal polypeptide (VIP). This diversity of inhibition allows the flexible regulation of neuronal responses within and between cortical areas. However, the exact roles of these interneuron subtypes and of excitatory pyramidal (Pyr) neurons in regulating neuronal network activity and establishing perception (via interactions between feedforward sensory and feedback attentional signals) remain largely unknown. To explore the regulatory roles of distinct neuronal types in cortical computation, we developed a computational microcircuit model with biologically plausible visual cortex layers 2/3 that combined Pyr neurons and the 3 inhibitory interneuron subtypes to generate network activity. In simulations with our model, inhibitory signals from PV and SOM neurons preferentially induced neuronal firing at gamma (30-80 Hz) and beta (20-30 Hz) frequencies, respectively, in agreement with observed physiological results. Furthermore, our model indicated that rapid inhibition from VIP to SOM subtypes underlies marked attentional modulation for low-gamma frequency (30-50 Hz) in Pyr neuron responses. Our results suggest the distinct but cooperative roles of inhibitory interneuron subtypes in the establishment of visual perception.
Identifiants
pubmed: 36130096
pii: 6706754
doi: 10.1093/cercor/bhac355
pmc: PMC10110453
doi:
Substances chimiques
Parvalbumins
0
Vasoactive Intestinal Peptide
37221-79-7
Somatostatin
51110-01-1
Banques de données
figshare
['10.6084/m9.figshare.20934352']
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
4459-4477Informations de copyright
© The Author(s) 2022. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.
Références
PLoS Comput Biol. 2015 Mar 31;11(3):e1004083
pubmed: 25826696
J Neurosci. 2013 Jan 2;33(1):17-25
pubmed: 23283318
J Neurophysiol. 2008 May;99(5):2158-82
pubmed: 18287553
J Neurosci. 2020 Sep 23;40(39):7436-7450
pubmed: 32817246
J Neurosci. 2015 Apr 29;35(17):6860-70
pubmed: 25926461
Neuron. 2018 Nov 21;100(4):953-963.e3
pubmed: 30318415
Proc Natl Acad Sci U S A. 2014 Oct 7;111(40):14332-41
pubmed: 25205811
Nature. 2014 May 8;509(7499):226-9
pubmed: 24695217
Nature. 2010 Apr 22;464(7292):1155-60
pubmed: 20414303
Neuron. 2013 May 22;78(4):729-39
pubmed: 23719166
Neuron. 2017 Dec 20;96(6):1403-1418.e6
pubmed: 29268099
J Neurophysiol. 1992 Apr;67(4):961-80
pubmed: 1588394
J Neurosci. 2014 Jul 9;34(28):9290-304
pubmed: 25009262
J Neurosci. 1991 Jun;11(6):1800-9
pubmed: 1675266
Neuron. 2020 May 6;106(3):388-403.e18
pubmed: 32142648
Neuron. 2013 May 8;78(3):523-36
pubmed: 23664617
PLoS Comput Biol. 2013;9(8):e1003164
pubmed: 23950699
J Neurophysiol. 2001 Oct;86(4):2011-28
pubmed: 11600658
Sci Adv. 2020 Apr 22;6(17):eaay5333
pubmed: 32426459
PLoS Comput Biol. 2018 Oct 18;14(10):e1006359
pubmed: 30335761
Curr Biol. 2013 Nov 4;23(21):2121-9
pubmed: 24139742
J Neurophysiol. 2002 Nov;88(5):2796-808
pubmed: 12424313
Neuron. 2009 Jan 29;61(2):301-16
pubmed: 19186171
J Neurophysiol. 1993 Oct;70(4):1553-69
pubmed: 7904301
Physiol Rev. 2010 Jul;90(3):1195-268
pubmed: 20664082
J Comp Neurol. 1994 Jun 22;344(4):543-58
pubmed: 7929891
J Neurosci. 2008 Jul 23;28(30):7679-86
pubmed: 18650344
Front Comput Neurosci. 2011 Jul 08;5:31
pubmed: 21779240
Elife. 2021 Nov 30;10:
pubmed: 34845986
Nat Commun. 2019 Nov 7;10(1):5055
pubmed: 31699994
Nat Rev Neurosci. 2010 Feb;11(2):100-13
pubmed: 20087360
Annu Rev Neurosci. 1998;21:47-74
pubmed: 9530491
Annu Rev Neurosci. 1985;8:407-30
pubmed: 3885829
Neuron. 2011 Dec 8;72(5):859-72
pubmed: 22153380
Front Comput Neurosci. 2013 Feb 07;6:102
pubmed: 23403536
PLoS Biol. 2005 Mar;3(3):e68
pubmed: 15737062
Neural Plast. 2021 Jan 18;2021:8874516
pubmed: 33531893
Cell Rep. 2018 Nov 6;25(6):1548-1560.e3
pubmed: 30404009
J Neurosci. 1990 Sep;10(9):3178-82
pubmed: 1697902
Cereb Cortex. 2002 Sep;12(9):936-53
pubmed: 12183393
Neuron. 2012 Sep 6;75(5):875-88
pubmed: 22958827
Brain Res. 1979 Dec 21;179(1):3-20
pubmed: 116716
J Neurosci. 2015 Jan 21;35(3):1089-105
pubmed: 25609625
J Neurosci. 1999 Nov 1;19(21):9587-603
pubmed: 10531461
Science. 2014 Aug 8;345(6197):660-5
pubmed: 25104383
Dev Neurobiol. 2011 Jan 1;71(1):45-61
pubmed: 21154909
Sci Rep. 2012;2:485
pubmed: 22761993
Neuron. 2009 May 28;62(4):578-92
pubmed: 19477158
Proc Natl Acad Sci U S A. 2012 Jul 3;109(27):11031-6
pubmed: 22615394
Nature. 2012 Oct 11;490(7419):226-31
pubmed: 23060193
Front Comput Neurosci. 2017 Apr 25;11:28
pubmed: 28487644
Neuron. 2016 Oct 5;92(1):240-251
pubmed: 27667008
IEEE Trans Neural Netw Learn Syst. 2021 Aug;32(8):3525-3537
pubmed: 32822305
Nature. 2016 Mar 17;531(7594):371-5
pubmed: 26958833
Neuron. 2017 Jan 18;93(2):299-307
pubmed: 28103478
Cereb Cortex. 2015 Nov;25(11):4415-29
pubmed: 25761638
Curr Biol. 2004 May 4;14(9):744-51
pubmed: 15120065
Sci Rep. 2017 May 12;7(1):1843
pubmed: 28500299
Neuron. 2021 Nov 3;109(21):3373-3391
pubmed: 34464597
PLoS Comput Biol. 2015 Dec 14;11(12):e1004584
pubmed: 26657024
J Neurosci. 2015 Oct 28;35(43):14585-601
pubmed: 26511248
Cereb Cortex. 2016 Oct;26(10):3964-76
pubmed: 27522074
J Neurosci. 1999 Jan 1;19(1):431-41
pubmed: 9870971
Front Neural Circuits. 2010 Mar 22;4:8
pubmed: 20407636
Proc Natl Acad Sci U S A. 1993 Nov 15;90(22):10469-73
pubmed: 8248133
Cogn Neurodyn. 2022 Aug;16(4):745-756
pubmed: 35847544
J Neurophysiol. 2016 Sep 1;116(3):1418-33
pubmed: 27486111
J Neurocytol. 2002 Mar-Jun;31(3-5):239-46
pubmed: 12815243
J Neurosci. 2017 Jul 12;37(28):6698-6711
pubmed: 28592697
Trends Neurosci. 2018 Oct;41(10):689-700
pubmed: 30274604
J Neurosci. 1999 Mar 1;19(5):1736-53
pubmed: 10024360
PLoS One. 2013 Dec 06;8(12):e80788
pubmed: 24324628
Nature. 2008 Aug 21;454(7207):995-9
pubmed: 18650810
Cogn Neurodyn. 2022 Aug;16(4):871-885
pubmed: 35847535
J Neurophysiol. 2016 Jun 1;115(6):3008-17
pubmed: 26961109
J Neurosci. 1993 Feb;13(2):768-81
pubmed: 7678860
Nature. 1979 Jul 12;280(5718):120-5
pubmed: 552600
J Comp Neurol. 2010 Jun 1;518(11):2051-70
pubmed: 20394058
Nat Neurosci. 2017 Jul;20(7):951-959
pubmed: 28481348
Nature. 2006 Feb 9;439(7077):733-6
pubmed: 16372022
PLoS Comput Biol. 2021 Mar 25;17(3):e1008829
pubmed: 33765007
Nature. 2012 Aug 16;488(7411):379-83
pubmed: 22878719
Neuron. 2017 Jan 18;93(2):315-322
pubmed: 28103479
Neuron. 2021 Dec 15;109(24):4050-4067.e12
pubmed: 34637706
Neuron. 2012 Jan 12;73(1):159-70
pubmed: 22243754
Nature. 2012 Aug 16;488(7411):343-8
pubmed: 22878717
Eur J Neurosci. 2011 Jul;34(1):146-57
pubmed: 21692884
Nature. 2013 Nov 28;503(7477):521-4
pubmed: 24097352
Curr Opin Neurobiol. 1993 Aug;3(4):586-94
pubmed: 8219726
J Neurophysiol. 2013 Feb;109(4):940-7
pubmed: 23197461
J Neurosci. 2004 Sep 29;24(39):8441-53
pubmed: 15456817
Nat Neurosci. 2013 Aug;16(8):1068-76
pubmed: 23817549
Curr Biol. 2013 May 20;23(10):890-4
pubmed: 23664971
Eur J Neurosci. 1993 Oct 1;5(10):1349-59
pubmed: 8275234
Neuron. 2015 Jan 21;85(2):390-401
pubmed: 25556836
Cereb Cortex. 2014 Mar;24(3):785-806
pubmed: 23203991
J Neurosci. 1983 May;3(5):1116-33
pubmed: 6188819
J Neurophysiol. 2013 Aug;110(4):964-72
pubmed: 23719206
Curr Biol. 2014 Jan 6;24(1):R18-R20
pubmed: 24405670
Curr Opin Neurobiol. 2010 Apr;20(2):183-90
pubmed: 20303256