Sex Difference in MasR Expression and Functions in the Renal System.
Journal
Journal of the renin-angiotensin-aldosterone system : JRAAS
ISSN: 1752-8976
Titre abrégé: J Renin Angiotensin Aldosterone Syst
Pays: England
ID NLM: 100971636
Informations de publication
Date de publication:
2022
2022
Historique:
received:
03
07
2022
revised:
10
08
2022
accepted:
17
08
2022
entrez:
23
9
2022
pubmed:
24
9
2022
medline:
28
9
2022
Statut:
epublish
Résumé
Renin-angiotensin system (RAS), as a critical system for controlling body fluid and hemostasis, contains peptides and receptors, including angiotensin 1-7 (Ang 1-7) and Mas receptor (MasR). Ang 1-7 implements its function via MasR. Ang II is another peptide in RAS that performs its actions via two Ang II type 1 and 2 receptors (AT1R and AT2R). The functions of AT2R and MasR are very similar, and both have a vasodilation effect, while AT1R has a vasoconstriction role. MasR affects many mechanisms in the brain, heart, blood vessels, kidney, lung, endocrine, reproductive, skeletal muscle, and liver and probably acts like a paracrine hormone in these organs. The effect of Ang 1-7 in the kidney is complex according to the hydroelectrolyte status, the renal sympathetic nervous system, and the activity level of the RAS. The MasR expression and function seem more complex than Ang II receptors and have interacted with Ang II receptors and many other factors, including sex hormones. Also, pathological conditions including hypertension, diabetes, and ischemia-reperfusion could change MasR expression and function. In this review, we consider the role of sex differences in MasR expression and functions in the renal system under physiological and pathological conditions.
Identifiants
pubmed: 36148474
doi: 10.1155/2022/1327839
pmc: PMC9482541
doi:
Substances chimiques
Peptide Fragments
0
Proto-Oncogene Mas
0
Proto-Oncogene Proteins
0
Receptors, G-Protein-Coupled
0
Angiotensin II
11128-99-7
Angiotensin I
9041-90-1
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
1327839Informations de copyright
Copyright © 2022 Samira Choopani and Mehdi Nematbakhsh.
Déclaration de conflit d'intérêts
The authors declare no conflict of interest.
Références
Curr Opin Nephrol Hypertens. 2007 Mar;16(2):122-8
pubmed: 17293687
PLoS One. 2013;8(1):e48425
pubmed: 23341867
Pharmacol Res. 2009 Apr;59(4):263-8
pubmed: 19166939
Pflugers Arch. 2003 Nov;447(2):223-30
pubmed: 14534790
Eur Heart J. 2005 Feb;26(4):369-75; discussion 322-4
pubmed: 15671045
Shock. 2015 Apr;43(4):395-404
pubmed: 25768373
Hypertension. 1999 Oct;34(4 Pt 2):964-8
pubmed: 10523392
Gen Physiol Biophys. 2014;33(3):365-72
pubmed: 24968411
Am J Physiol Renal Physiol. 2016 Jul 1;311(1):F195-206
pubmed: 26823279
Am J Hypertens. 2007 Oct;20(10):1119-24
pubmed: 17903697
Hypertension. 1996 Apr;27(4):875-84
pubmed: 8613263
J Hypertens. 2006 Oct;24(10):1971-8
pubmed: 16957556
Physiol Rev. 2018 Jan 1;98(1):505-553
pubmed: 29351514
Curr Hypertens Rep. 2013 Feb;15(1):71-9
pubmed: 23180053
Regul Pept. 2002 Jun 15;106(1-3):67-70
pubmed: 12047912
Exp Physiol. 2017 Dec 1;102(12):1700-1715
pubmed: 28940861
J Physiol Pharmacol. 2014 Oct;65(5):633-9
pubmed: 25371522
Adv Biomed Res. 2018 Jan 30;7:12
pubmed: 29456983
J Hypertens. 2009 Oct;27(10):1988-2000
pubmed: 19593210
J Am Soc Hypertens. 2008;2(6):425-430
pubmed: 19198668
Regul Pept. 2006 Dec 10;137(3):128-33
pubmed: 16934886
Adv Pharmacol Sci. 2016;2016:7294942
pubmed: 27034657
FASEB J. 2021 Mar;35(3):e21419
pubmed: 33566370
Gend Med. 2012 Feb;9(1):21-32
pubmed: 22266307
Int J Biol Sci. 2011;7(8):1077-92
pubmed: 21927577
Mol Cell Endocrinol. 2010 Feb 5;315(1-2):188-94
pubmed: 19879325
Am J Physiol Renal Physiol. 2006 Jun;290(6):F1497-506
pubmed: 16403834
Int J Nephrol. 2021 Apr 20;2021:6618061
pubmed: 33986960
Adv Pharmacol Sci. 2015;2015:801053
pubmed: 26421009
Res Pharm Sci. 2018 Apr;13(2):177-180
pubmed: 29606972
Clin Auton Res. 2020 Oct;30(5):393-408
pubmed: 32860555
J Urol. 2004 Dec;172(6 Pt 2):2563-9
pubmed: 15538209
Physiol Int. 2016 Mar;103(1):13-20
pubmed: 27030624
Cell. 1986 Jun 6;45(5):711-9
pubmed: 3708691
Hypertension. 2003 Oct;42(4):781-6
pubmed: 12874087
J Am Soc Nephrol. 1999 Jan;10 Suppl 11:S30-9
pubmed: 9892138
Acta Physiol (Oxf). 2012 Oct;206(2):150-6
pubmed: 22775972
Clin Sci (Lond). 2010 Jul 23;119(9):385-94
pubmed: 20528771
Hypertension. 2004 May;43(5):970-6
pubmed: 15007027
Hypertension. 2001 Jan;37(1):72-76
pubmed: 11208759
Kidney Int. 2009 Jun;75(11):1184-1193
pubmed: 19262461
Clin Sci (Lond). 2015 May 1;128(10):649-63
pubmed: 25495544
Hypertension. 1998 Jan;31(1 Pt 2):356-61
pubmed: 9453328
J Hypertens. 2001 Nov;19(11):2001-9
pubmed: 11677365
Circulation. 1998 Jun 9;97(22):2197-201
pubmed: 9631868
Res Pharm Sci. 2016 Jan-Feb;11(1):65-72
pubmed: 27051434
Acta Pharmacol Sin. 2008 Jul;29(7):829-37
pubmed: 18565281
Am J Physiol Renal Physiol. 2009 Feb;296(2):F337-46
pubmed: 19052102
Free Radic Res. 2011 May;45(5):575-84
pubmed: 21381899
Hypertens Res. 2006 Nov;29(11):865-74
pubmed: 17345786
Am J Physiol. 1996 Jan;270(1 Pt 2):F141-7
pubmed: 8769832
Hypertension. 2010 Oct;56(4):658-66
pubmed: 20713916
Nephrol Dial Transplant. 2009 Jun;24(6):1744-52
pubmed: 19103735
Am J Physiol Regul Integr Comp Physiol. 2013 Sep;305(5):R459-63
pubmed: 23883676
Int J Vasc Med. 2021 Mar 01;2021:6643485
pubmed: 33747565
Hypertension. 1996 Mar;27(3 Pt 2):523-8
pubmed: 8613197
FEBS Lett. 1995 Jan 2;357(1):27-32
pubmed: 8001672
Am J Physiol Heart Circ Physiol. 2005 Sep;289(3):H1013-9
pubmed: 15833808
Mol Cell Endocrinol. 2012 Jan 2;348(1):104-11
pubmed: 21827824
Hypertension. 2004 Oct;44(4):490-6
pubmed: 15326087
Circ Res. 2000 Sep 1;87(5):E1-9
pubmed: 10969042
Contrib Nephrol. 2004;143:77-89
pubmed: 15248357
J Pathol. 2011 Dec;225(4):618-27
pubmed: 22009550
Kidney Blood Press Res. 1997;20(4):233-9
pubmed: 9398028
Exp Physiol. 2008 May;93(5):528-37
pubmed: 18156169
Compr Physiol. 2012 Oct;2(4):2733-52
pubmed: 23720263
Hypertension. 1999 Aug;34(2):296-301
pubmed: 10454457
Mol Syst Biol. 2020 Jul;16(7):e9610
pubmed: 32715618
J Renin Angiotensin Aldosterone Syst. 2015 Jun;16(2):292-300
pubmed: 25070352
Cardiovasc Res. 2004 Jun 1;62(3):587-93
pubmed: 15158151
Int J Hypertens. 2021 Feb 20;2021:8820646
pubmed: 33688433
Hypertension. 1995 Jul;26(1):164-70
pubmed: 7607720
J Renin Angiotensin Aldosterone Syst. 2020 Apr-Jun;21(2):1470320320919607
pubmed: 32370637
Am J Physiol Heart Circ Physiol. 2003 Jun;284(6):H1985-94
pubmed: 12573992
Am J Physiol Heart Circ Physiol. 2005 Oct;289(4):H1351-8
pubmed: 15894569
Kidney Int. 2015 Feb;87(2):359-69
pubmed: 25075768
Am J Physiol Regul Integr Comp Physiol. 2008 Apr;294(4):R1220-6
pubmed: 18287217
Kidney Int. 2005 Nov;68(5):2189-96
pubmed: 16221218
Circulation. 2005 May 24;111(20):2605-10
pubmed: 15897343
Am J Physiol Renal Physiol. 2019 Sep 1;317(3):F670-F682
pubmed: 31339773
Int J Hypertens. 2012;2012:808726
pubmed: 22319645
Eur J Pharmacol. 2007 Apr 30;561(1-3):144-50
pubmed: 17320855
J Renin Angiotensin Aldosterone Syst. 2011 Dec;12(4):413-9
pubmed: 21436210
Hypertension. 2006 Oct;48(4):572-8
pubmed: 16908757
Res Pharm Sci. 2019 Feb;14(1):12-19
pubmed: 30936928
Am J Physiol Renal Physiol. 2009 Feb;296(2):F398-405
pubmed: 19004932
Hypertens Res. 2014 Jul;37(7):616-20
pubmed: 24599018
J Biol Chem. 2000 Oct 27;275(43):33238-43
pubmed: 10924499
J Diabetes Res. 2015;2015:674047
pubmed: 26442284
Braz J Med Biol Res. 1997 Apr;30(4):503-13
pubmed: 9251772
Br J Pharmacol. 2015 Sep;172(18):4443-4453
pubmed: 26075703
Hypertension. 2007 Jan;49(1):185-92
pubmed: 17116756
Circulation. 2005 Apr 12;111(14):1806-13
pubmed: 15809376
Am J Physiol Renal Physiol. 2002 Nov;283(5):F934-43
pubmed: 12372768
Kidney Blood Press Res. 2015;40(5):467-77
pubmed: 26394118
J Hypertens. 2007 Dec;25(12):2421-5
pubmed: 17984663
Am J Physiol Heart Circ Physiol. 2006 Nov;291(5):H2166-72
pubmed: 16766648
Gend Med. 2008;5 Suppl A:S65-75
pubmed: 18395684
Endocrine. 2004 Jul;24(2):161-5
pubmed: 15347843
ScientificWorldJournal. 2009 Jun 30;9:522-35
pubmed: 19578709
Mol Cell Endocrinol. 2017 May 15;447:98-105
pubmed: 28254489
Clin Sci (Lond). 2010 Feb;118(4):269-79
pubmed: 19698082