Prussian Blue Staining to Visualize Iron Oxide Nanoparticles.
Ferric iron
Histology
Perls’ staining
Superparamagnetic iron oxide nanoparticles
Journal
Methods in molecular biology (Clifton, N.J.)
ISSN: 1940-6029
Titre abrégé: Methods Mol Biol
Pays: United States
ID NLM: 9214969
Informations de publication
Date de publication:
2023
2023
Historique:
entrez:
24
9
2022
pubmed:
25
9
2022
medline:
28
9
2022
Statut:
ppublish
Résumé
Iron deposits in cells and tissues can be detected by ex vivo histological examination through the Prussian blue (PB) staining. This practical, inexpensive, and highly sensitive technique involves the treatment of fixed tissue sections and cells with acid solutions of ferrocyanides that combine with ferric ion forming a bright blue pigment (i.e., ferric ferrocyanide). The staining can be applied to visualize iron oxide nanoparticles (IONPs), versatile magnetic nanosystems that are used in various biomedical applications and whose localization is usually required at a higher resolution than that enabled by in vivo tracking techniques.
Identifiants
pubmed: 36152263
doi: 10.1007/978-1-0716-2675-7_26
doi:
Substances chimiques
Ferric Compounds
0
Ferrocyanides
0
Magnetite Nanoparticles
0
Iron
E1UOL152H7
ferric ferrocyanide
TLE294X33A
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
321-332Informations de copyright
© 2023. The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature.
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