Trace determination of tetrahydrocannabinol (THC) in cosmetic products by stir bar sorptive dispersive microextraction followed by liquid chromatography-tandem mass spectrometry.

Cannabinoids Cosmetic samples Dispersive-based microextraction Magnetic sorbent Stir bar sorptive dispersive microextraction Tetrahydrocannabinol

Journal

Talanta
ISSN: 1873-3573
Titre abrégé: Talanta
Pays: Netherlands
ID NLM: 2984816R

Informations de publication

Date de publication:
01 Feb 2023
Historique:
received: 19 07 2022
revised: 06 09 2022
accepted: 08 09 2022
pubmed: 25 9 2022
medline: 15 12 2022
entrez: 24 9 2022
Statut: ppublish

Résumé

An analytical method for the determination of tetrahydrocannabinol (THC) at trace level in cosmetics is presented. As psychoactive compound, the presence of THC in consumer products should be avoided. However, it might be unintentionally present in cannabidiol-rich or hemp-based products by contamination or isomerization of cannabidiol. Due to the low concentrations expected, a sensitive and selective method is necessary for the analytical control of these products. In this sense, the presented method is based on stir bar sorptive dispersive microextraction (SBSDME) followed by liquid chromatography-tandem mass spectrometry (LC-MS/MS). In this work, a magnetic composite made of CoFe

Identifiants

pubmed: 36152610
pii: S0039-9140(22)00730-5
doi: 10.1016/j.talanta.2022.123934
pii:
doi:

Substances chimiques

Dronabinol 7J8897W37S

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

123934

Informations de copyright

Copyright © 2022 The Authors. Published by Elsevier B.V. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Auteurs

Cristian Azorín (C)

GICAPC Research Group, Department of Analytical Chemistry, University of Valencia, 46100 Burjassot, Valencia, Spain.

Juan L Benedé (JL)

GICAPC Research Group, Department of Analytical Chemistry, University of Valencia, 46100 Burjassot, Valencia, Spain.

Alberto Chisvert (A)

GICAPC Research Group, Department of Analytical Chemistry, University of Valencia, 46100 Burjassot, Valencia, Spain. Electronic address: alberto.chisvert@uv.es.

Amparo Salvador (A)

GICAPC Research Group, Department of Analytical Chemistry, University of Valencia, 46100 Burjassot, Valencia, Spain.

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Classifications MeSH