Further insight into the genetic diversity of Entamoeba coli and Entamoeba hartmanni.


Journal

The Journal of eukaryotic microbiology
ISSN: 1550-7408
Titre abrégé: J Eukaryot Microbiol
Pays: United States
ID NLM: 9306405

Informations de publication

Date de publication:
03 2023
Historique:
revised: 16 09 2022
received: 02 08 2022
accepted: 16 09 2022
pubmed: 29 9 2022
medline: 15 3 2023
entrez: 28 9 2022
Statut: ppublish

Résumé

Despite the species' wide distribution, studies of the genetic diversity within Entamoeba coli and Entamoeba hartmanni remain limited. In the present study, we provide further insight into the genetic diversity of both species based on analysis of partial nuclear small subunit ribosomal DNA sequences generated from human fecal DNAs from samples collected in Africa, South America, and Europe. Reinforcing the previous recognition that E. coli is a species complex, our data confirm the existence of the two subtypes, ST1 and ST2, previously identified plus, potentially, a new subtype, ST3. While ST1 appears to be genetically quite homogenous, ST2 shows a substantial degree of intrasubtype diversity. ST2 was more common in samples collected outside Europe, whereas ST1 showed no geographical restriction. The potentially novel subtype is represented to date exclusively by sequences from South American and African samples. In contrast to previous reports, our new data also indicate substantial variation in E. hartmanni that could also support the establishment of subtypes within this species. Here, however, no links were identified between subtype and geographical origin.

Identifiants

pubmed: 36168968
doi: 10.1111/jeu.12949
doi:

Substances chimiques

Interleukin-1 Receptor-Like 1 Protein 0
DNA, Ribosomal 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e12949

Informations de copyright

© 2022 The Authors. Journal of Eukaryotic Microbiology published by Wiley Periodicals LLC on behalf of International Society of Protistologists.

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Auteurs

Christen Rune Stensvold (CR)

Department of Bacteria, Parasites and Fungi, Statens Serum Institut, Copenhagen S, Denmark.

Kasandra Ascuña-Durand (K)

Laboratorio de Microbiología Molecular, Facultad de Medicina, Universidad Nacional de San Agustín, Arequipa, Peru.

Amal Chihi (A)

Laboratoire de Recherche 'Parasitologie Médicale, Biotechnologies et Biomolécules', LR 16-IPT-06, Institut Pasteur de Tunis, Université Tunis El-Manar, Tunis, Tunisia.

Salem Belkessa (S)

Department of Biology, Faculty of Nature and Life Sciences, Ziane Achour University of Djelfa, Djelfa, Algeria.

Özgür Kurt (Ö)

Department of Medical Microbiology, School of Medicine, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey.

Ayman El-Badry (A)

Department of Microbiology, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.

Mark van der Giezen (M)

Department of Chemistry, Bioscience and Environmental Engineering, University of Stavanger, Stavanger, Norway.

C Graham Clark (CG)

Department of Infection Biology, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK.

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