Fabrication and Functionalisation of Nanocarbon-Based Field-Effect Transistor Biosensors.

biosensors carbon nanotubes field-effect transistors graphene point-of-care diagnostics surface functionalisation

Journal

Chembiochem : a European journal of chemical biology
ISSN: 1439-7633
Titre abrégé: Chembiochem
Pays: Germany
ID NLM: 100937360

Informations de publication

Date de publication:
05 12 2022
Historique:
revised: 03 10 2022
received: 17 05 2022
pubmed: 5 10 2022
medline: 25 1 2023
entrez: 4 10 2022
Statut: ppublish

Résumé

Nanocarbon-based field-effect transistor (NC-FET) biosensors are at the forefront of future diagnostic technology. By integrating biological molecules with electrically conducting carbon-based platforms, high sensitivity real-time multiplexed sensing is possible. Combined with their small footprint, portability, ease of use, and label-free sensing mechanisms, NC-FETs are prime candidates for the rapidly expanding areas of point-of-care testing, environmental monitoring and biosensing as a whole. In this review we provide an overview of the basic operational mechanisms behind NC-FETs, synthesis and fabrication of FET devices, and developments in functionalisation strategies for biosensing applications.

Identifiants

pubmed: 36193790
doi: 10.1002/cbic.202200282
pmc: PMC10092808
doi:

Types de publication

Journal Article Review Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.

Langues

eng

Sous-ensembles de citation

IM

Pagination

e202200282

Subventions

Organisme : Biotechnology and Biological Sciences Research Council
ID : BB/M009122/1
Pays : United Kingdom
Organisme : Biotechnology and Biological Sciences Research Council
ID : BB/H003746/1
Pays : United Kingdom
Organisme : Wellcome Trust
ID : AC1910IF14
Pays : United Kingdom
Organisme : Biotechnology and Biological Sciences Research Council
ID : BB/M000249/1
Pays : United Kingdom
Organisme : Wellcome Trust
Pays : United Kingdom

Informations de copyright

© 2022 The Authors. ChemBioChem published by Wiley-VCH GmbH.

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Auteurs

Chang-Seuk Lee (CS)

Department of Chemistry, School of Physical and Chemical Sciences, Queen Mary University of London, Mile End Road, London, E1 4NS, UK.

Rebecca E A Gwyther (REA)

Molecular Biosciences Division, School of Biosciences, Cardiff University, Cardiff, CF10 3AX, UK.

Mark Freeley (M)

Department of Chemistry, School of Physical and Chemical Sciences, Queen Mary University of London, Mile End Road, London, E1 4NS, UK.

Dafydd Jones (D)

Molecular Biosciences Division, School of Biosciences, Cardiff University, Cardiff, CF10 3AX, UK.

Matteo Palma (M)

Department of Chemistry, School of Physical and Chemical Sciences, Queen Mary University of London, Mile End Road, London, E1 4NS, UK.

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